Skip to main content

Bupropion for Bipolar Disorder User Reviews (Page 4)

Brand names: Wellbutrin XL, Wellbutrin SR, Forfivo XL, Aplenzin Budeprion Budeprion SR

Reviews for Bupropion

Commonly mentioned side effects
  • Cat...
  • Taken for 1 to 6 months
  • April 22, 2015

"I was started on Wellbutrin about 2 months ago, along with Lamictal for mood stabilization. I reluctantly got on it after a year free of meds (when I got hit with a bad case of Seasonal Depression beginning in fall and lasting through March and some of April, after a move to mostly gloomy Asheville, NC). I started off on half a tablet of 75 mg regular release. Then I went up an extra half a tab. At first, I thought it was great, and then I started to feel low down again and went up to 150 mg. Slowly, I noticed feeling quite agitated and almost aggressive. I cut back down to just one tab and then half a tab, and still the side effects persisted, along with horrible anxiety and restlessness. So no more for me."

2 / 10
Was this helpful?YesNo
9 Report
  • Bip...
  • Taken for 6 months to 1 year
  • December 14, 2022

"I loved bupropion, it is the first antidepressant that worked for me after trying a long list of other meds (Prozac, Lexapro, Abilify...). Bupropion is the only one that actually made me feel good, especially without any sexual side effects (important for a 23-year-old in college :P), but 5 months in, this medication started giving me seizures...sooo...that's not cool. Definitely worth a try though. Was perfect up until the seizures :P."

6 / 10
Was this helpful?YesNo
2 Report
  • Kar...
  • Taken for 1 to 6 months
  • June 30, 2022

"In my experience, I've seen an improvement. I started with 150 mg and my depression episodes stopped being so frequent, my mania episodes last a lot less. I'm now increasing to 300 mg, because even though they are not as frequent, they are still very intense. But I've tried fluoxetine, that one made everything worse."

9 / 10
Was this helpful?YesNo
1 Report

Frequently asked questions

  • Mat...
  • Taken for 2 to 5 years
  • July 7, 2022

"This is the only med that works for my depressive states without causing terrible side effects. SSRIs make me very tired and sexually anhedonic. Bupropion feels like a couple of cups of coffee and does not interfere with sexual enjoyment (if anything, it enhances it a little bit, but that may just be its antidepressant effect). I am currently on 150 mg of the XL once a day but just started taking it again after several years on SSRIs (I started on those due to some perceived anxiety that turned out to be temporary). I used to take two doses of the SR but do not remember how many mg. I also take 300 mg of lamotrigine to avoid manic and mixed phases, and the combo seems to work for me."

10 / 10
Was this helpful?YesNo
1 Report
  • Zed...
  • May 23, 2020

"One of the bests, any meds if used responsibly and keep the dosage as low as possible, especially for bipolars."

9 / 10
Was this helpful?YesNo
19 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
  • Anonymous
  • January 12, 2012

"I'm not sure yet what to think. I've been on 300 mg of Bupropion XL for one week and feel angry, edgy, and cranky."

5 / 10
Was this helpful?YesNo
37 Report
  • jen...
  • August 31, 2011

Bupropion "When I first started taking it, it gave me anxiety, but once finding the right dose, it works very well with no adverse side effects."

9 / 10
Was this helpful?YesNo
28 Report
  • ren...
  • August 9, 2010

Bupropion "I have taken Wellbutrin SR for about 8 months, and I can tell a great difference between the brand name and the generic."

9 / 10
Was this helpful?YesNo
32 Report
  • Gra...
  • March 19, 2009

Bupropion "Keeps me even-tempered, whereas I used to be moody in the afternoons when I started getting tired."

8 / 10
Was this helpful?YesNo
23 Report
  • vol...
  • May 14, 2011

Bupropion "I took Wellbutrin for 2 months at 100 mg to treat bipolar disorder type I. Wellbutrin did help my mood, but I discontinued due to nausea, dizziness, and hand tremors."

4 / 10
Was this helpful?YesNo
20 Report
  • gol...
  • Taken for 1 to 6 months
  • October 13, 2018

"Take this drug with a mood stabilizer. Great for motivation!"

10 / 10
Was this helpful?YesNo
10 Report
  • Kka...
  • Taken for less than 1 month
  • September 22, 2020

"Bupropion gave me extreme irritability! Everything made me want to just scream. I became a complete psycho after trying for one week. Worst experience with a med ever!"

1 / 10
Was this helpful?YesNo
7 Report
  • vic...
  • Taken for 10 years or more
  • April 7, 2024

"I have been on this medication for over 10 years, of course that's in combination with other medications, and I don't want to ever change it. Now I have neuropathy so it's doing double duty."

10 / 10
Was this helpful?YesNo
2 Report
  • Gui...
  • Taken for 1 to 6 months
  • March 7, 2022

"5 weeks L 200 mg / Wellbutrin 300 mg. Suddenly, I feel a bump of energy. More than 5 months laid down on a bed. Start running today. Hope for all of us. Don't give up."

10 / 10
Was this helpful?YesNo
3 Report
  • FL ...
  • January 28, 2018

"The side effects can, at times, be overwhelming."

3 / 10
Was this helpful?YesNo
6 Report

Are you taking this medicine?

Your review helps others make informed decisions.
Write a review
Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.

Learn more about Bipolar Disorder

Care guides

Symptoms and treatments

Medicine.com guides (external)