Bupropion / dextromethorphan and Sexual Dysfunction: What Users Say

• NYC...
• Taken for 1 to 6 months
• January 31, 2023

For Major Depressive Disorder "I have been on 5 different antidepressants (bupropion, Prozac, Zoloft, Lexapro, ketamine) and I can say that Auvelity is by far the best one so far. No sexual side effects, and my mood feels the best it has ever been in 5 years now since my depression started. Auvelity is even more effective than the ketamine infusions and much less of a hassle. Definitely recommend."

• Ano...
• Taken for 1 to 6 months
• June 9, 2025

"I was taking Zoloft but had experienced sexual side effects and this medication was recommended by my psychiatrist. I understood that it was related to Wellbutrin. I had taken Wellbutrin before with no problems. Auvelity worked well for me. I also noticed the medication evened out my downtime for my carbidopa-levodopa taken for my Parkinson's. Auvelity seemed to spread the dopamine in the carbidopa-levodopa thereby resulting in less downtime of PD medication and less tremor symptoms."

• Jas...
• Taken for 1 to 6 months
• July 7, 2024

For Major Depressive Disorder "The absolute best medication I have been on for depression. I have been on everything in the last 20 years and nothing has worked like this. I'm happy, motivated, sleep well, have emotions, and I don't feel hopeless. I am a better mother as well. Such an amazing medication. In the beginning, I did feel 'high' for a lack of better words and lightheaded. I clenched my jaw a bit as well. It’s been 4 months now and I feel great. No weight gain. Sexual side effects were very temporary."

• Cra...
• Taken for 1 to 6 months
• December 5, 2024

For Major Depressive Disorder "Really the first anti I've been on that made me feel like it was working. The first three weeks I had a cough med high that was pleasant. I've been on Auvelity for 6 months and had some strange side effects. I will gladly take losing my sex drive over losing myself in a dark pit. I can't say I'm doing a lot better, but I'm actually working with it for a change. I've been on them all, placebo effects almost always, but this hasn't diminished. Every antidepressant or antipsychotic did the same thing… start off great, then a few months later I was more aware of my depression and completely lethargic. I know this isn't listed on what Auvelity treats, but I suffered headaches almost daily and migraines 6-10 per month, but they have much improved. The daily headaches 90% improved. Migraines 75% maybe more. That alone is happiness."

• Jac...
• Taken for less than 1 month
• March 9, 2023

For Major Depressive Disorder "I have been taking Auvelity for about a week. While the medication is working and my mood is better, the sexual side effects are not. I cannot find anywhere if the side effects diminish over time. The mood is great, energy is back, motivation, and everything. The nausea is okay."