Bupropion / dextromethorphan and Nausea: What Users Say

• Kat...
• Taken for less than 1 month
• December 4, 2022

For Major Depressive Disorder "It's my 4th day in, and while it's caused a bit of nausea, I already feel better. I failed 9 SSRIs/SNRIs and had even turned to Spravato. This med has been added to Spravato, and I feel more upbeat and hopeful. I'm using the discount card to make this affordable."

• Mes...
• Taken for less than 1 month
• April 5, 2023

For Major Depressive Disorder "I am on week two now. I would say this medication works fast. I was so depressed, but it changed the way I think and feel. No side effects for me, but just on the first day, I felt nauseous. I like it for real. I will keep you updated, guys."

• Mic...
• Taken for less than 1 month
• January 3, 2023

For Major Depressive Disorder "I am starting my third week. I had nausea and headache up until today. Hopefully, they won't come back. I can't shake the suicidal thoughts, so not sure how the med is working. Hopefully, the thoughts will subside with time."

• Jac...
• Taken for less than 1 month
• March 9, 2023

For Major Depressive Disorder "I have been taking Auvelity for about a week. While the medication is working and my mood is better, the sexual side effects are not. I cannot find anywhere if the side effects diminish over time. The mood is great, energy is back, motivation, and everything. The nausea is okay."

• hai...
• Taken for less than 1 month
• August 13, 2025

For Major Depressive Disorder "I’ve tried a number of medications for my anxiety and depression over the years. Prozac was the only one that truly helped, though after about 5 years the benefits started to subside. Over the last few months, I’ve tried a few other medicines. I tried Auvelity hoping it might improve mood and motivation, and I was hopeful due to positive reviews and the slight feelings of improvement I noticed. In the first week, however, I experienced very vivid dreams, flu-like symptoms including nausea, faintness, and overheating, as well as sleep disruption. My body felt extremely hyper-aware, as if I could feel every heartbeat and even subtle eye movements, and I never got to the twice-a-day dosing (only took 1 per day). After several weeks, I noticed no meaningful improvement in mood, energy, or motivation. I think those with sensitive nervous systems or heightened sensitivity to medications may find the side effects difficult to tolerate, and for me, they outweighed any benefits."