Z-Pak and Anxiety: What Users Say

• Chr...
• Taken for less than 1 month
• May 18, 2023

"I was prescribed a Z-Pak before a trip out of the country for potential strep throat. A family member had strep, and I was feeling off prior to the trip, so I called a teledoctor, and they prescribed the Z-Pak. I took the first dose. Within 45 minutes, I had diarrhea, and my heart rate shot over 120 bpm. I attributed these symptoms to anxiety prior to the trip. Went to bed and woke up around 2:30 am sweating, my heart racing, and my body shaking/jerking. Needless to say, the trip was canceled. Anxiety, headaches, and diarrhea lasted days after, along with sleeping hours upon end. Literally felt like I was hit by a truck. I will not be taking a Z-Pak again."

• hhl...
• Taken for less than 1 month
• August 9, 2020

For Bacterial Infection "Z-Pak works well for clearing up strep throat, however, it caused *severe* appetite loss. Loose stools 1x a day. I lost 7 lbs in 3 days on this. Obviously, weight can be gained back, and the strep is gone - but ask your doctor for a script of Zofran with this! & Diflucan. Increased my anxiety a ton at night as well. Could not sleep. Pros - works. Cons - you will never want to eat, also a lot of anxiety at night from this."

• Ava...
• Taken for less than 1 month
• August 24, 2021

For Bacterial Infection "I was experiencing a tension headache off and on for close to two weeks. I suspected I had a sinus infection and went to the ER because I couldn’t get in to see my PCP for weeks. I took the Z-Pak as prescribed (my last dose was last Thursday). I still feel like I have a sinus headache in addition to dizziness, fatigue, diarrhea, and anxiety. I felt worse after taking it, I ended up back in the ER and was told they didn’t find a sinus infection at all, and I need to follow up with a neurologist because they couldn’t find anything on the CT that could cause the headaches either! I had a horrible reaction to a medication last year (Lexapro), which increased my anxiety symptoms. I have been in therapy and doing well with no panic attacks in months. I feel like I possibly set myself back taking the Z-Pak. It was my first and last time taking it, I never experienced these side effects taking Amoxicillin. I had to take time off from work to recoup, I want this out of my system as quickly as possible!!"