Apalutamide and Fatigue: What Users Say

• Ann...
• Taken for 1 to 6 months
• March 21, 2022

For Prostate Cancer "Starting Erleada in Sept 2021, immediately experienced side effects, severe edema in both legs, slightly elevated glucose numbers, higher blood pressure, muscle weakness in both legs, rash, discoloration in my skin tone, and at times some dizziness. After speaking with oncology and primary physicians, both concluded it was Erleada. Other medications that I was on were adjusted, and with careful monitoring of my condition, several months later, PSA dropped to under zero, non-detectable levels, glucose and high blood pressure are now reading normal. Only side effects that persist are the fatigue and weakness in both legs. Weakness in muscles is slowly regaining strength, some slight water retention in the ankles and feet, and is being monitored by the primary physician. Overall, the medication addressed my PSA numbers and has accomplished and assisted in bringing down the numbers to under zero. Rough start, but my health numbers are good now."

• EA2...
• Taken for 1 to 6 months
• June 16, 2024

For Prostate Cancer "Been on Erleada for 2.5 months. Was previously on Bicalutamide, but PSA started rising to 2.6. After 2 mos, PSA dropped to 0.23, so it appears to be working well. Changed to a plant-based diet and I continue to workout 5 days a week. Side effects have been hardly felt, however, consist of very slight off & on joint pain at night and/or in the gym. Lost some weight, occasional fatigue (but nothing a 20 min power nap can't take care of), no hot flashes at all, no ED, no skin rashes, no diarrhea at all. Hoping next PSA check drops it even lower, but so far so good. Well tolerated."

• big...
• Taken for 6 months to 1 year
• May 28, 2024

For Prostate Cancer "Did help but side effects were terrible, such as falling and blurred vision. Fatigue and weakness were bad from the onset."

• Tho...
• Taken for 1 to 6 months
• December 28, 2024

For Prostate Cancer "I have been on Erleada for almost 5 months. My PSA has been undetectable for 2.5 months. The side effects are very difficult, mainly the bone pain, hot flashes, loss of energy, I am weak and frail."