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Apalutamide User Reviews & Ratings

Brand names: Erleada

Apalutamide has an average rating of 8.0 out of 10 from a total of 26 reviews on Drugs.com. 81% of reviewers reported a positive experience, while 8% reported a negative experience.

Condition Avg. Rating Reviews Compare
Prostate Cancer
8.0
 26 reviews for Prostate Cancer 59 medications

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Reviews for Apalutamide

  • IP ...
  • Taken for 6 months to 1 year
  • February 11, 2021

Erleada (apalutamide) for Prostate Cancer "77 years old, prostatectomy 16 years ago, PSA began doubling every month in 2017, Stage 4 PCa diagnosed, PSA surged to >50, began and still on Firmagon. After beginning Erleada at 4 pills with my evening meal, my PSA dropped roughly 80% every month thereafter. It's been <0.01 for months now. The only side effect I've noticed is physical weakness when I work out or play hard (I'm a very active athlete). My docs attribute that to my very low (single digit on the 300-800 scale) testosterone, not to the med itself. My poor balance, muscle loss, and some muscle and joint aches and pains are probably due respectively and primarily to 25 years with Meniere's disease, closed gyms plus no T, and prior injuries or current overuse. I'm extremely pleased with Erleada, and it gives my oncologist a proven (in my case) fallback position as he tweaks my medication protocol to keep confusing and thwarting my widespread cancer."

9 / 10
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50 Report
  • BMG...
  • Taken for 6 months to 1 year
  • December 3, 2023

Erleada (apalutamide) for Prostate Cancer "Lowered my PSA very quickly, below 1.0. Have been on the drug for 6 months. Tiredness to the point of falling asleep whenever I sit down, especially after meals. Memory loss or lack of concentration, which is moderate. Some agitation, mild personality/depression changes. And taste affected for cold water and milk, both tasting terrible, and previously loved both. This is starting to resolve after 6 months. Age 69 with CRPC, not metastatic."

6 / 10
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9 Report
  • Ann...
  • Taken for 1 to 6 months
  • March 21, 2022

Erleada (apalutamide) for Prostate Cancer "Starting Erleada in Sept 2021, immediately experienced side effects, severe edema in both legs, slightly elevated glucose numbers, higher blood pressure, muscle weakness in both legs, rash, discoloration in my skin tone, and at times some dizziness. After speaking with oncology and primary physicians, both concluded it was Erleada. Other medications that I was on were adjusted, and with careful monitoring of my condition, several months later, PSA dropped to under zero, non-detectable levels, glucose and high blood pressure are now reading normal. Only side effects that persist are the fatigue and weakness in both legs. Weakness in muscles is slowly regaining strength, some slight water retention in the ankles and feet, and is being monitored by the primary physician. Overall, the medication addressed my PSA numbers and has accomplished and assisted in bringing down the numbers to under zero. Rough start, but my health numbers are good now."

8 / 10
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17 Report

Frequently asked questions

  • Mik...
  • Taken for 1 to 6 months
  • April 6, 2024

Erleada (apalutamide) for Prostate Cancer "Been on four pills a day for two months. I continue to go to the gym and walk but some mornings I need to push myself. The most challenging are the hot flashes but willingly accept them. Dr appointment next month and hoping for low PSA. Overall life is good."

9 / 10
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7 Report
  • Lt ...
  • July 11, 2024

Erleada (apalutamide) for Prostate Cancer "I'll be honest, I took Erleada for 7 days. The side effects were hot flashes, swelling, and dizziness, so I stopped taking it and went back to my oncologist. He basically told me that I have 2 choices: take the Erleada and live, or don't take it and die, as I'm in stage 4 metastatic with no chance of being cured. Despite all that, my PSA has dropped to 0.06 from 16."

9 / 10
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  • Mik...
  • Taken for 6 months to 1 year
  • April 18, 2024

Erleada (apalutamide) for Prostate Cancer "Because of my other medication I cannot really separate the side effects of taking Erleada except for the latest event that I am experiencing. About four days ago, I went to lay down and my brain seemed to be swirling around inside my head. The same feeling when I sat up. I did not have any dizziness when walking. I had been pulling weeds in the yard and the pollen was all over the place and me, so I thought it was a reaction to it. My sinuses did not react to the pollen. I mean no runny nose or coughing. So, in thinking about it, I read where taking an antihistamine would relieve the dizzy feeling. The drug has lowered my PSA from 3.98 to 0.01. I also take Eligard injections, so hot flashes and other side effects have to be shared by the two drugs."

10 / 10
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6 Report
  • XXX...
  • Taken for 2 to 5 years
  • January 26, 2024

Erleada (apalutamide) for Prostate Cancer "Metastatic prostate cancer to the ribs. Use with Gnax and Calcium and Vitamin D. At 42 months, PSA begins to rise but tumor appears to have been suppressed on bone scan. 64 g x 4 daily. Dizziness. Fatigue. Falls."

8 / 10
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5 Report
  • EA2...
  • Taken for 1 to 6 months
  • June 16, 2024

Erleada (apalutamide) for Prostate Cancer "Been on Erleada for 2.5 months. Was previously on Bicalutamide, but PSA started rising to 2.6. After 2 mos, PSA dropped to 0.23, so it appears to be working well. Changed to a plant-based diet and I continue to workout 5 days a week. Side effects have been hardly felt, however, consist of very slight off & on joint pain at night and/or in the gym. Lost some weight, occasional fatigue (but nothing a 20 min power nap can't take care of), no hot flashes at all, no ED, no skin rashes, no diarrhea at all. Hoping next PSA check drops it even lower, but so far so good. Well tolerated."

8 / 10
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  • Tom...
  • Taken for 6 months to 1 year
  • August 10, 2023

For Prostate Cancer "Really turned around my prostate cancer. Cancer was caught very late; I was in a bad way. Much weight loss, 20kg, very weak, very thin, ghost-looking, and feeling very ill. After about a month of taking apalutamide along with another drug, my health changed enormously. I couldn't believe it. Though I am not gaining much weight, I feel so much better. I'm suffering from many of the side effects but I'm managing those... fatigue mainly and some lost appetite. I am very pleased with the drug. I'm taking 4 tabs per day."

10 / 10
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  • Bil...
  • May 5, 2023

Erleada (apalutamide) for Prostate Cancer "Loss of body hair, loss of libido, falls, and ataxia were all significant. BP unchanged. Did not have GI symptoms or weight loss. The cost is awful. Have had no evidence of an increase in PSA from undetectable since starting."

9 / 10
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  • mal...
  • Taken for 1 to 2 years
  • August 26, 2024

For Prostate Cancer "PC went to stage 4 12 months ago, so I was started on APA and ADT. As of now, my PSA has reduced to 0.2. I tolerate it quite well. Hot flushes 2/3 daily, some loss of taste, tire easily, though I am 75. I get some dark thoughts from time to time, which I did not have on previous treatments, but overall, I am very grateful."

9 / 10
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  • Vie...
  • Taken for 1 to 2 years
  • July 3, 2024

For Prostate Cancer "It is working the way it is intended to, but my husband suffered so badly from the hot flashes and excessive sweating with any sort of physical effort after the first year of treatment, that he landed in the hospital with very low sodium of 123 (normal is 135). This caused him to fall three days in a row and was too weak to walk. I had to have the ambulance come and take him. Thankfully, he did not break any bones. Patients should be advised to stay hydrated with electrolytes and have their sodium monitored."

8 / 10
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  • Jam...
  • March 4, 2024

For Prostate Cancer "I am prescribed four 60 mg tablets per day and have been taking apalutamide for 24 months. Generally, I tolerate it very well. I was experiencing hot flashes from my Lupron injections, so I can't say that apalutamide has added to the number, around 30 or so, that I experience a day. I have a feeling of malaise and fatigue that seemed to begin shortly after I started the apalutamide treatments, yet I can cope with it. Overall, the treatments are working and working well, so I am very, very grateful."

10 / 10
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  • Mik...
  • Taken for 6 months to 1 year
  • July 29, 2024

For Prostate Cancer "I took it for 6 months along with Lupron and 6 weeks of radiation at MGBH in Boston. Cancer appears to be gone. I stopped the apalutamide with the consent of my doctor because frequent urination and occasional loose bowels were making it difficult to leave the house. It’s only been a short time, but those two problems are gone."

9 / 10
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  • big...
  • Taken for 6 months to 1 year
  • May 28, 2024

Erleada (apalutamide) for Prostate Cancer "Did help but side effects were terrible, such as falling and blurred vision. Fatigue and weakness were bad from the onset."

8 / 10
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6 Report
  • Gaf...
  • Taken for 6 months to 1 year
  • November 21, 2023

Erleada (apalutamide) for Prostate Cancer "Restored bone health, stopped all bone and muscular pain with little to no side effects."

10 / 10
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8 Report
  • Tom...
  • July 7, 2023

Erleada (apalutamide) for Prostate Cancer "1 month and a half on Erleada, I developed hot flashes and penis and testicular size reduction. I developed a bad case of the hives. The urologist stopped taking Erleada."

2 / 10
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8 Report
  • Bob...
  • Taken for 1 to 6 months
  • December 1, 2020

Erleada (apalutamide) for Prostate Cancer "After two months on Erleada, my PSA is lower. Taking the drug four times is a challenge. So far, side effects are minor."

7 / 10
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16 Report
  • Ple...
  • Taken for less than 1 month
  • February 15, 2024

Erleada (apalutamide) for Prostate Cancer "Early stages only, blurred vision, hot flushes, tiredness. PSA count decreased dramatically to 0.54 after 2 weeks of medication so it definitely works."

8 / 10
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5 Report
  • Ric...
  • Taken for 1 to 6 months
  • March 24, 2023

Erleada (apalutamide) for Prostate Cancer "Prostate-specific antigen (PSA) dropped below 1, but the severe joint pain and constipation were intolerable."

1 / 10
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7 Report
  • Tho...
  • Taken for 1 to 6 months
  • December 28, 2024

Erleada (apalutamide) for Prostate Cancer "I have been on Erleada for almost 5 months. My PSA has been undetectable for 2.5 months. The side effects are very difficult, mainly the bone pain, hot flashes, loss of energy, I am weak and frail."

8 / 10
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1 Report
  • Raf...
  • November 10, 2024

Erleada (apalutamide) for Prostate Cancer "Waking up with mild headaches almost every day. Taking longer to fall asleep and sleeping less soundly."

8 / 10
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1 Report
  • ber...
  • Taken for 1 to 6 months
  • July 22, 2023

Erleada (apalutamide) for Prostate Cancer "Severe weakness, fatigue, and weight loss, secondary to the fact that everything tastes terrible, so no appetite."

6 / 10
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3 Report
  • Spi...
  • Taken for 1 to 2 years
  • September 9, 2024

For Prostate Cancer "Joint pain, weight gain, lethargy, cramping, and sleeplessness."

10 / 10
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1 Report
  • Dba...
  • Taken for 1 to 6 months
  • November 18, 2023

For Prostate Cancer "Worked! Side effects: fatigue, hot flashes, dysgeusia."

10 / 10
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1 Report
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.