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Apalutamide Dosage

Medically reviewed by Last updated on Sep 8, 2023.

Applies to the following strengths: 60 mg; 240 mg

Usual Adult Dose for Prostate Cancer

240 mg orally once a day



Renal Dose Adjustments

Mild to moderate renal impairment: No adjustment required.
Severe or end-stage renal impairment: Data not available

Liver Dose Adjustments

Mild (Child-Pugh A) or moderate (Child-Pugh) hepatic impairment: No adjustment recommended.
Severe (Child-Pugh C) hepatic impairment: Data not available

Dose Adjustments

If a patient experiences a Grade 3 or greater toxicity or an intolerable side effect, hold dosing until symptoms improve to Grade 1 or less or original grade, then resume at the same dose or a reduced dose (180 mg or 120 mg).



Safety and efficacy have not been established in patients younger than 18 years.

Consult WARNINGS section for additional precautions.


Data not available

Other Comments

Administration advice:

Storage requirements:

Patient advice:

Frequently asked questions

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.