How long do you have to take Erleada (apalutamide) for?
Official answer
by Drugs.comErleada (apalutamide) is usually taken until cancer progresses past a certain point or you start to have unacceptable side effects.
- In the SPARTAN clinical trial (NCT01946204) using apalutamide for men with castration-resistant metastasis-free prostate cancer, some patients were still using apalutamide at 36 months.
- In the TITAN clinical trial (NCT02489318) studying men using apalutamide for metastatic, castration-sensitive prostate cancer, some patients were still taking it after 2 years.
Erleada is an androgen blocker.
- Androgens, such as testosterone, can help prostate cancer growth.
- As Erleada blocks androgens effect on the tumor, it makes it harder for the tumor to advance.
- This means patients taking Erleada have a longer overall survival and have a longer time before their disease progresses.
References
- Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer: https://www.nejm.org/doi/full/10.1056/NEJMoa1715546
- Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer: https://www.nejm.org/doi/full/10.1056/nejmoa1903307
- Erleada Professional Medication Information: https://www.drugs.com/pro/erleada.html
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