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What does abiraterone therapy do?

Medically reviewed by Carmen Fookes, BPharm. Last updated on Nov 7, 2021.

Official answer

by Drugs.com

Abiraterone works by blocking the effects of an enzyme (called CYP17) that is found in testicular, adrenal, and prostate tumor tissue that is necessary for the production of testosterone and other androgens. By blocking this enzyme, abiraterone reduces the production of testosterone and other androgens which stimulate prostate cancer cells to grow. Abiraterone inhibits androgen at 3 sources—the testes, the adrenal glands, AND the tumor itself.

Abiraterone is not considered chemotherapy, rather it is a type of hormone therapy that is used along with prednisone to treat men with prostate cancer that has spread to other parts of the body (metastasized).


References
  • Abiraterone. Updated 10/2021. Apotex Corp. https://www.drugs.com/pro/abiraterone.html#s-34090-1
  • How ZYTIGA® Works. Zytiga.com https://www.zytiga.com/taking-zytiga

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