What type of drug is Talzenna?
Medically reviewed by Drugs.com. Last updated on Sep 8, 2020.
Talzenna (talazoparib) used for the treatment of patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), HER2-negative locally advanced or metastatic breast cancer. Patients are selected for this treatment based on an FDA-approved diagnostic test.
PARP inhibitors are used to treat cancers that have mistakes in their DNA repair genes, such as with the BRCA gene mutation. PARP is a protein that is involved with cancer cell growth, regulation and repair. PARP inhibitors stop the cancer cells from being repaired which leads to cell death and a reduction in tumor growth. PARP inhibitors are used to treat cancers such as:
- ovarian cancer
- fallopian tube cancer
- peritoneal cancer
- breast cancer
- prostate cancer
Other PARP inhibitors include:
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