How effective is Casodex for prostate cancer?
Casodex (biclutamide) is an anti-androgen type of hormone therapy used to treat prostate cancer that has metastasized (spread to other parts of the body.)
When Casodex is used in combination with a luteinizing hormone-releasing hormone (LHRH) analog (either leuprolide depot or goserelin implant) Casodex + LHRH analog are
- more effective than leuprolide on its own
- is just as effective as flutamide + leuprolide.
A clinical study for Stage D2 Prostate Carcinoma comparing leuprolide with leuprolide + flutamide showed:
- leuprolide + flutamide treatment increased survival time by 7 months which was a 25% improvement
Another clinical trial was completed comparing treatment of Casodex + LHRH analog with flutamide + LHRH analog for Stage D2 Prostate Carcinoma. The results showed both treatment options had similar effects with no significant difference between:
- survival time (time to death)
- time to tumor progression
- quality of life
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- Casodex Information for Consumers
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