How effective is Casodex for prostate cancer?
Official Answer
by Drugs.comCasodex (biclutamide) is an anti-androgen type of hormone therapy used to treat prostate cancer that has metastasized (spread to other parts of the body.)
When Casodex is used in combination with a luteinizing hormone-releasing hormone (LHRH) analog (either leuprolide depot or goserelin implant) Casodex + LHRH analog are
- more effective than leuprolide on its own
- is just as effective as flutamide + leuprolide.
A clinical study for Stage D2 Prostate Carcinoma comparing leuprolide with leuprolide + flutamide showed:
- leuprolide + flutamide treatment increased survival time by 7 months which was a 25% improvement
Another clinical trial was completed comparing treatment of Casodex + LHRH analog with flutamide + LHRH analog for Stage D2 Prostate Carcinoma. The results showed both treatment options had similar effects with no significant difference between:
- survival time (time to death)
- time to tumor progression
- quality of life
References
- Casodex Medication Information: https://www.drugs.com/pro/casodex.html
- Eulexin (flutamide) Medication Information: https://www.drugs.com/pro/eulexin.html
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Drug Information
- Casodex Information for Consumers
- Casodex Information for Healthcare Professionals (includes dosage details)
- Side Effects of Casodex (detailed)
Related Support Groups
- Casodex (5 questions, 18 members)
- Prostate Cancer (48 questions, 144 members)