Amlodipine / benazepril and Swelling: What Users Say

• Anonymous
• Taken for 6 months to 1 year
• May 9, 2012

For High Blood Pressure "I've been taking amlodipine/benazepril for over six months, and I experience knee pain, swelling of feet, and hands daily. Before this medicine, I used to walk 4 miles per day. I can barely walk two miles due to the pain in my knees. Although it has reduced my blood pressure, I cannot handle the side effects."

• Anonymous
• Taken for 6 months to 1 year
• May 9, 2012

For High Blood Pressure "I've been taking amlodipine/benazepril for over six months, and I experience knee pain, swelling of feet, and hands daily. Before this medicine, I used to walk 4 miles per day. I can barely walk two miles due to the pain in my knees. Although it has reduced my blood pressure, I cannot handle the side effects."

• Gyp...
• July 23, 2019

Amlodipine / benazepril for High Blood Pressure "I was on this medication for approximately two weeks, the time given for the medication to effectively take its full course. Well, for the first week, it did its job at lowering my BP, however, if there were side effects I got from it, then it would have been the moodiness. I was tired to the point of exhaustion, hungry all the time, and that horrible dry cough was so bad I thought I was going to cough a lung out, it sounded like I was a serious smoker. Exactly on the 14th day of taking it - July 3rd - my top lip began to swell. By the time I made it to the ER, my top lip had swelled 5x its natural size. Glad I got to the hospital before I went into anaphylaxis. Come to find out I am severely allergic to both amlodipine and benazepril. Terrifying experience."

• iti...
• March 7, 2008

Amlodipine / benazepril for High Blood Pressure "I have been taking Lotrel now for 9 years. I also take Synthroid with it. Granted, I have gained a lot of weight. Whereas before I weighed 140, I now weigh 205. If there is a way I can lose this weight, I will be happy to. I have problems with my left ankle, it is always swollen. Only when I can stay off of it does it go down."

• Anonymous
• March 9, 2009

Amlodipine / benazepril for High Blood Pressure "I have taken Lotrel for 9 years. It reduced my blood pressure moderately, but this month I went to the emergency room with severe swelling of my face, and my lips were huge. Was told to get off Lotrel since this ACE inhibitor can cause angioedema, which was the diagnosis. Have also had tingling of the lips and tongue for the last 4 years and now wonder if Lotrel contributed to that."

• sam...
• January 7, 2008

Amlodipine / benazepril for High Blood Pressure "I have developed severe swelling in my fingers. It is constant, causing numbness in the fingertips and pain in the joints - mostly in the middle of the night. I love having my blood pressure lowered, though."

• Anonymous
• September 8, 2011

For High Blood Pressure "I tried four medicines before amlodipine/benazepril. I am a 40-year-old female. I run 20 miles a week and do yoga twice a week. I have not had any muscle or joint issues. I have had swollen and tender gums and a bad taste in my mouth that compels me to chew gum at all times (besides while I am sleeping or eating). It was the first medicine to bring down my blood pressure. So, I hope to stay on it and hope the side effects simmer down."

• Mea...
• Taken for 2 to 5 years
• August 6, 2021

Amlodipine / benazepril for High Blood Pressure "Amlodipine by itself did not work to lower my BP and caused swelling and weight gain. Lotrel, after working with my Dr to find the right dosage, has worked well for me (5/10) - normal BP and no side effects. Unfortunately, even with daily workouts and a healthy diet, I have high BP by genetics, been taking since I have been 35."

• Nik...
• Taken for 6 months to 1 year
• June 4, 2019

For High Blood Pressure "I'm on the generic amlodipine with benazepril, and I've had swelling in the face, neck, throat, and hands. I need to know, has anyone else had an experience with swelling after having a drink of any sort with alcohol? Every time I drink alcohol, I have swelling really bad. I had to stop and think what I was taking. I then looked at the side effects of this medicine, and it's giving me the same side effects that I have."

• Anonymous
• Taken for 1 to 6 months
• December 16, 2019

For High Blood Pressure "Was given this after amlodipine alone caused much edema. This was no better. Still had edema, chest pressure, and the added delight of the “ACE inhibitor cough.” Terrible drug. I’ve been off it a week and still coughing to the point of almost throwing up."

• Exh...
• Taken for 10 years or more
• May 21, 2021

For High Blood Pressure "I’ve taken this drug for 13 years. I’ve recently started with swelling in my ankles. The tingling and crawling nerve feeling in my head is awful. I have had a cough for a few years, and they have given me several different reasons for the cough. My knees have been hurting and hurt more after my ankles swell. I have gained 45 pounds, and I can lose 10 pounds, but they come back on right away. The doctors have done blood panels and found no reason for the weight gain. They say I need to lose the weight, so I had them take me off the medicine and put me on two separate pills instead of doing a split pill of 10/20 or 10/40."

• mea...
• January 30, 2010

Amlodipine / benazepril for High Blood Pressure "I was on Lotrel for approximately 3 to 4 months. Had severe swelling and pain in legs and feet. Did not do much in making my blood pressure any lower. No longer on this medicine."

• cra...
• July 22, 2008

Amlodipine / benazepril for High Blood Pressure "Lotrel has worked for me with a low dosage. The higher dosage caused side effects. Tried five different blood pressure medicines before, and they all had side effects such as swelling or leg cramps."

• CMD...
• Taken for less than 1 month
• December 12, 2024

For High Blood Pressure "Worked great, BP came down, and I was happy. But then, after a month, my feet, calves, and hands started swelling up!! I stopped."