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ACE inhibitors with calcium channel blocking agents

What are ACE inhibitors with calcium channel blocking agents?

ACE inhibitors with calcium channel blocking agents is a combination medicine containing both an angiotensin-converting-enzyme inhibitor (ACE inhibitor) and a calcium channel blocker.This combination is often used to treat hypertension.

An ACE inhibitor blocks the angiotensin-converting-enzyme from converting angiotensin I to angiotensin II. This results in a decrease in angiotensin II causing vasodilation and therefore a reduction in blood pressure.

Calcium channel blockers block calcium from entering cells of the heart and smooth muscle in the walls of blood vessels. This results in vasodilation of the arteries, a reduction in heart contraction force, a slowing of heart rate and a reduction in aldosterone production. These effects cause a decrease in blood pressure in the hypertensive patient and a decrease in symptoms in patients with angina or ischemic heart disease.

List of ACE inhibitors with calcium channel blocking agents:

View by  Brand | Generic
Drug Name Reviews Avg. Ratings
Tarka (Pro)
Generic name: trandolapril / verapamil
5 reviews
9.1
Lotrel (Pro)
Generic name: amlodipine / benazepril
26 reviews
6.9
Amlobenz
Generic name: amlodipine / benazepril
0 reviewsAdd rating
Lexxel
Generic name: enalapril/felodipine
0 reviewsAdd rating
Prestalia (Pro)
Generic name: amlodipine / perindopril
0 reviewsAdd rating
For ratings, users were asked how effective they found the medicine while considering positive/adverse effects and ease of use (1 = not effective, 10 = most effective).

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

See Also

Medical conditions associated with ACE inhibitors with calcium channel blocking agents: