Skip to Content

User Reviews for Lotrel

Condition Avg. Rating Reviews Compare
High Blood Pressure  
6.0
27 reviews 266 medications

Reviews may be moderated to correct grammar/spelling or remove inappropriate language. Reviews that appear to be created by parties with a vested interest in the medication will not be published.

Reviews for Lotrel

1freddy · Taken for less than 1 month November 25, 2012

For High Blood Pressure: “I have been on Lotrel for 3 weeks and I'm having several side effects. I'm very lethargic, no energy (no energy to exercise), I even fall asleep an hour after taking the medicine, depressed, my head tingles, my fasting glucose has risen at least 10 points and the worst is I have gained 15 pounds! I had lost 30lbs and maintained since August. It was difficult and the weight loss was slow. My eating hasn't increased. My husband agrees. Morbid obesity can raise your blood pressure. This medicine is pulling my blood pressure down but the side effects are essentially making things worse. This medication isn't a good fit for me.”

6 / 10
Was this helpful?YesNo
HFNorthC March 9, 2012

For High Blood Pressure: “I tried several other medicines, but Lotrel seems to be very effective in lowering my blood pressure. I have a had no side effects. I am 49 years old and Africian American. On this medicine 10 months now.”

9 / 10
Was this helpful?YesNo
itip March 7, 2008

For High Blood Pressure: “I have been taking Lotrel now for 9 years. I also take synthorid with it. Granted I have gained a lot of weigth. Where as before I weighted 140 I now weight 205. If there is a way I can loose this weight I will be happy to. I have problems with my left angle, it is always swelled. Only when I can stay off of it does it go down. ”

Was this helpful?YesNo
CC · Taken for 6 months to 1 year February 22, 2019

For High Blood Pressure: “WEIGHT GAIN...30 LBS in a couple of months along with being so lethargic I could not function. It has lowered my BP but with this weight gain and lack of energy, it is affecting everything in my life. I am on a strict diet and exercise and it is not moving.”

Was this helpful?YesNo
GypsyQueen July 23, 2019

For High Blood Pressure: “I was on this medication for approximately two weeks the time given for the medication to effectively take it's full course. Well for the first week, it did it's job at lowering my BP however if there was a side effects I got it from it, then it would have been the moodiness, I was tired to the point of exhaustion, hungry all the time and that horrible dry cough was so bad I though I was going to cough a lung out, it sounded like I was a serious smoker. Exactly on the 14th day on taking it - July 3rd - my top lip began to swell, by the time I made it to the ER my top lip had swelled 5x it's natural size, Glad I got to the hospital before I went into Anaphylaxis Come to find out I am severely allergic to both Amlodipine and benazepril, Terrifying experience”

3 / 10
Was this helpful?YesNo
Anonymous March 9, 2009

For High Blood Pressure: “I have taken Lotrel for 9 years. It reduced my blood pressure moderately, but this month I went to the emergency room with severe swelling of my face and my lips were huge. Was told to get off Lotrel since this ACE inhibitor can cause angioedema which was the diagnosis. Have also had tingling of the lips and tongue for the last 4 years and now wonder if Lotrel contributed to that. ”

5 / 10
Was this helpful?YesNo
Gypsy March 29, 2021

For High Blood Pressure: “My Mom weighed 163 when the new Dr.here put my Moma on Lotrel. Years later she passed and she weighed 204. I've been on it too for 10 plus years! I struggle with fatigue, nasal congestion and constantly have to clear my throat...AND I have a problem with my weight... Weight gain...is it from the Lotrel....”

2 / 10
Was this helpful?YesNo
MiniMe2 December 22, 2007

For High Blood Pressure: “I have severe muscle spasms in the back of my legs. I have been on it for about 2 months. My knees are fine, I just turned 50. The drug is doing its job. Sometimes I get dizzy when I get up fast or have to bend over to pick something up.”

Was this helpful?YesNo
JOSIE L July 12, 2010

For High Blood Pressure: “I have been on lotrel for three years. I never had knee problems but never connected the medicine with the symptoms until I started searching for side effects, by others. I spoke with my doctor and he has recommended lisiniopril/hydrochlorothiazide. See if problem with knees will improve. Because knee pain is terrible!”

3 / 10
Was this helpful?YesNo
samodio January 7, 2008

For High Blood Pressure: “I hav developed severe swelling in my fingers. It is constant causing numbness in the fingertips and pain in the joints - mostly in the middle of the night. I love having my blood pressure lowered though.”

Was this helpful?YesNo
Gmmk August 2, 2011

For High Blood Pressure: “Developed severe nocturnal leg cramps. Occured nightly between 5am and 7am. After 3 months I discontinued and went back to Diltiazem. Cramps stopped next day.”

3 / 10
Was this helpful?YesNo
dgames July 7, 2014

For High Blood Pressure: “I'm a 58 year old male having been on Lotrel 10-20mg for several years now. I have not had any side effects, with this medication and have seen it is controlling my high blood pressure.”

9 / 10
Was this helpful?YesNo
Susiev.h. August 24, 2016

For High Blood Pressure: “Tired/sexual dysfunction i.e. Very hard to achieve orgasm.”

8 / 10
Was this helpful?YesNo
Anonymous November 21, 2008

For High Blood Pressure: “The side effects I have are body aches, weight gain and lightheadedness.”

5 / 10
Was this helpful?YesNo
meanashair January 30, 2010

For High Blood Pressure: “I was on Lotrel for approximately 3/4 months. Had severe swelling and pain in legs and feet. Did not do much in making my blood pressure any lower. No longer on this medicine.”

1 / 10
Was this helpful?YesNo
Anonymous February 25, 2009

For High Blood Pressure: “Great at lowering blood pressure (250 to 174 using 10 mg). But body aches, dull headache often noted. My doctor wanted me on 20 mg but that was too uncomfortable.”

6 / 10
Was this helpful?YesNo
Anonymous January 11, 2011

For High Blood Pressure: “Been taking for 5/40 10 years. no problems at all and keeps the pressure down.”

9 / 10
Was this helpful?YesNo
crabbydee July 22, 2008

For High Blood Pressure: “Lotrel has worked for me with a low dosage. The higher dosage caused side effects. Tried five different blood pressure medicines before and they all had side effects such as swelling or leg cramps.”

10 / 10
Was this helpful?YesNo
Daddy of Four February 26, 2008

For High Blood Pressure: “I been taking Lotrel over a year now. I am not showing any side effects at all. I am 45 now and have four kids under four. That right FOUR. Lotrel has helped my HBP.”

10 / 10
Was this helpful?YesNo
Anonymous October 2, 2009

For High Blood Pressure: “While I have not had any major side effects, just occasional coughing bouts, I have had a tough time losing weight...but have not gained.”

Was this helpful?YesNo
Anonymous September 12, 2009

For High Blood Pressure: “This drug is very effective but also very expensive.”

6 / 10
Was this helpful?YesNo
Anonymous September 6, 2008

For High Blood Pressure: “so far so good. I have had sleep problems with all the Blood pressure meds given to me.”

7 / 10
Was this helpful?YesNo
reddawk April 30, 2009

For High Blood Pressure: “I am a 45 year old male - been on Lotrel for 3 years with no problems.”

10 / 10
Was this helpful?YesNo
ILoveKonataIzumi · Taken for 2 to 5 years September 28, 2017

For High Blood Pressure: “Lower blood pressure and improved cardiovascular health with no side effects at all.”

10 / 10
Was this helpful?YesNo
Anonymous July 13, 2009

For High Blood Pressure: “Had side effects.”

5 / 10
Was this helpful?YesNo

This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.