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Lotrel and Weight Gain: What Users Say

Weight gain: mentioned by 6 users (20.0%)

Based on user experiences from 30 Lotrel reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 26.7%
swelling 23.3%
weight gain 20.0%
cough 10.0%
pain 10.0%

Reviews for Lotrel

Commonly mentioned side effects
  • 1fr...
  • Taken for less than 1 month
  • November 25, 2012

For High Blood Pressure "I have been on Lotrel for 3 weeks and I'm having several side effects. I'm very lethargic, no energy (no energy to exercise), I even fall asleep an hour after taking the medicine. I feel depressed, my head tingles, my fasting glucose has risen at least 10 points, and the worst is I have gained 15 pounds! I had lost 30 lbs and maintained since August. It was difficult, and the weight loss was slow. My eating hasn't increased. My husband agrees. Morbid obesity can raise your blood pressure. This medicine is pulling my blood pressure down, but the side effects are essentially making things worse. This medication isn't a good fit for me."

6 / 10
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110 Report
  • CCa...
  • Taken for 6 months to 1 year
  • February 22, 2019

For High Blood Pressure "Weight gain... 30 lbs in a couple of months, along with being so lethargic I could not function. It has lowered my BP, but with this weight gain and lack of energy, it is affecting everything in my life. I am on a strict diet and exercise, and it is not moving."

2 / 10
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23 Report
  • Gyp...
  • March 29, 2021

For High Blood Pressure "My mom weighed 163 when the new Dr. here put my mom on Lotrel. Years later she passed, and she weighed 204. I've been on it too for 10 plus years! I struggle with fatigue, nasal congestion, and constantly have to clear my throat... AND I have a problem with my weight... Weight gain... is it from the Lotrel...."

2 / 10
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13 Report
  • Mea...
  • Taken for 2 to 5 years
  • August 6, 2021

For High Blood Pressure "Amlodipine by itself did not work to lower my BP and caused swelling and weight gain. Lotrel, after working with my Dr to find the right dosage, has worked well for me (5/10) - normal BP and no side effects. Unfortunately, even with daily workouts and a healthy diet, I have high BP by genetics, been taking since I have been 35."

9 / 10
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7 Report
  • Not...
  • Taken for 1 to 2 years
  • September 29, 2021

For High Blood Pressure "Been taking this medication on and off. It brings the BP a bit down, but the side effects are horrible: coughing, pain in the knees, tired a lot, no energy, weight gain. For something that is supposed to help the symptoms, why not fix the problem instead of adding new ones?"

2 / 10
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8 Report
  • Anonymous
  • November 21, 2008

For High Blood Pressure "The side effects I have are body aches, weight gain, and lightheadedness."

5 / 10
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41 Report

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