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Lotrel and Swelling: What Users Say

Swelling: mentioned by 7 users (23.3%)

Based on user experiences from 30 Lotrel reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

tiredness 26.7%
swelling 23.3%
weight gain 20.0%
cough 10.0%
pain 10.0%

Reviews for Lotrel

Commonly mentioned side effects
  • Gyp...
  • July 23, 2019

For High Blood Pressure "I was on this medication for approximately two weeks, the time given for the medication to effectively take its full course. Well, for the first week, it did its job at lowering my BP, however, if there were side effects I got from it, then it would have been the moodiness. I was tired to the point of exhaustion, hungry all the time, and that horrible dry cough was so bad I thought I was going to cough a lung out, it sounded like I was a serious smoker. Exactly on the 14th day of taking it - July 3rd - my top lip began to swell. By the time I made it to the ER, my top lip had swelled 5x its natural size. Glad I got to the hospital before I went into anaphylaxis. Come to find out I am severely allergic to both amlodipine and benazepril. Terrifying experience."

3 / 10
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27 Report
  • iti...
  • March 7, 2008

For High Blood Pressure "I have been taking Lotrel now for 9 years. I also take Synthroid with it. Granted, I have gained a lot of weight. Whereas before I weighed 140, I now weigh 205. If there is a way I can lose this weight, I will be happy to. I have problems with my left ankle, it is always swollen. Only when I can stay off of it does it go down."

5 / 10
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57 Report
  • Anonymous
  • March 9, 2009

For High Blood Pressure "I have taken Lotrel for 9 years. It reduced my blood pressure moderately, but this month I went to the emergency room with severe swelling of my face, and my lips were huge. Was told to get off Lotrel since this ACE inhibitor can cause angioedema, which was the diagnosis. Have also had tingling of the lips and tongue for the last 4 years and now wonder if Lotrel contributed to that."

5 / 10
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48 Report
  • sam...
  • January 7, 2008

For High Blood Pressure "I have developed severe swelling in my fingers. It is constant, causing numbness in the fingertips and pain in the joints - mostly in the middle of the night. I love having my blood pressure lowered, though."

8 / 10
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41 Report
  • Mea...
  • Taken for 2 to 5 years
  • August 6, 2021

For High Blood Pressure "Amlodipine by itself did not work to lower my BP and caused swelling and weight gain. Lotrel, after working with my Dr to find the right dosage, has worked well for me (5/10) - normal BP and no side effects. Unfortunately, even with daily workouts and a healthy diet, I have high BP by genetics, been taking since I have been 35."

9 / 10
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7 Report

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  • mea...
  • January 30, 2010

For High Blood Pressure "I was on Lotrel for approximately 3 to 4 months. Had severe swelling and pain in legs and feet. Did not do much in making my blood pressure any lower. No longer on this medicine."

1 / 10
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40 Report
  • cra...
  • July 22, 2008

For High Blood Pressure "Lotrel has worked for me with a low dosage. The higher dosage caused side effects. Tried five different blood pressure medicines before, and they all had side effects such as swelling or leg cramps."

10 / 10
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31 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.