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Amitriptyline for Neuropathic Pain User Reviews (Page 2)

Amitriptyline has an average rating of 6.8 out of 10 from a total of 36 reviews for the off-label treatment of Neuropathic Pain. 53% of reviewers reported a positive experience, while 19% reported a negative experience.

Reviews for Amitriptyline

  • Anonymous
  • Taken for 5 to 10 years
  • September 17, 2021

"Initially it helped me sleep through pain and worked as intended for over a year. I ran out of medication for 2 weeks due to circumstances out of my control and it caused horrible withdrawal and gave me a psychotic episode. The effects of which I’m still dealing with today. It no longer works for me. Also, don’t take this with alcohol. nothing terrible happens, it just makes you feel really weird. dosage 10/mg every day, been on it for over 4 years."

2 / 10
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12 Report
  • Cliff
  • Taken for 1 to 6 months
  • February 1, 2022

"I started taking 10mg amitriptyline at night in September 2021 for peripheral neuropathy. I've just weaned myself of them a week ago, January 2022. I was having terrible night sweats and palpitations, dizziness, bunged up nose, dry mouth. The pain is back but I no longer feel like I'm going to drop dead."

3 / 10
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9 Report
  • Barista
  • Taken for 1 to 2 years
  • October 26, 2021

"Gained 46lbs and began to have myoclonic jerks while taking this. It helped for headaches but not much for other pains. It also put me to sleep every night. When I had to stop, I had really bad withdrawals. Now I don't know how to go to sleep either."

1 / 10
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9 Report

Frequently asked questions

  • Annie...
  • Taken for less than 1 month
  • May 25, 2022

"I took one 10mg amitriptyline to treat Central Pain Syndrome, which is severe, constant nerve pain resulting from a damaged nervous system (caused by Lyme disease.) When I woke up the next day, my face, hands, and ankles were so swollen, making the pain even worse. I am MISERABLE. Called my neurologist after one dose and told him absolutely not. I had the same problem with Lyrica and I’m so desperate for relief I don’t know what to do. Despite my poor health, I am generally in good spirits or at least calm, but amitriptyline made me feel agitated and I hate feeling like that without having any reason to feel that way. I will never touch this medicine again."

1 / 10
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7 Report
  • Jan
  • Taken for 2 to 5 years
  • August 19, 2023

"I've been taking amitriptyline for a few years now to manage headaches caused by Chiari Malformation. This medication has restored my life to almost normal. When I started the medication, I was experiencing approximately 25 Chiari headaches daily. With continued use of this medication, I now have Chiari headaches once a month or less. I don't want to consider what my life would be like without this life-changing medication."

10 / 10
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4 Report

Are you taking this medicine?

  • Aano
  • March 13, 2021

"I had chronic headaches as well as depression and anxiety. 10mg of Amitriptyline has stopped all headaches, and I generally am in a better mood. I'm not sure whether it is actually helping my depression chemically, or reducing headaches to put me in a better mood, overall it’s definitely helped."

9 / 10
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  • Shesa...
  • Taken for 5 to 10 years
  • August 28, 2021

"Varies in time for effect on sleeping. Moderate nerve pain relief noticed following day, if you haven't fallen out of bed in the night. I will normally take 50 mg per night but not every night as I don't like waking up on floor. For sleeping, can take 30 mins to 2 hours to work. So no late meals. Caused me to nod off at work following morning DURING calls. I'd wake up and be talking to a new patient! No one seemed to notice luckily as phonelines were quite bad. And I always requested late shifts anyway, due to meds. But I do mind about falling out of bed. But then I mind about sciatic pain it sucks."

5 / 10
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7 Report
  • Renee
  • Taken for 10 years or more
  • September 26, 2021

"I’ve taken this for chronic pain, sleep & intractable migraine prophylaxis since 1984. Otherwise, MD was going to place me in medical induced coma for deadly insomnia (only 1-2 hrs sleep daily for months). Came off twice unsuccessfully & nearly miscarried fetus 3X. It is a wonder drug that has helped immensely for decades at a very small dose."

9 / 10
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  • Lilia...
  • Taken for 1 to 6 months
  • December 27, 2020

"Had trigeminal neuralgia 16 days after shingles on right side of face. Took amitriptyline 25mg for 8 weeks. My scalp pain 6/10 was instantly gone on first night but facial pain 4/10 persists till today since July 2020. I'm using heat compress only for relief now."

8 / 10
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7 Report
  • Jim
  • Taken for 1 to 6 months
  • September 30, 2019

"After a motorcycle accident I have had neck pain and headaches for 15 years. Went on endep and most of pain has subsided so Doc was right about nerve pain. I would like to increase from 20mg to see if can touch my bad moods."

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  • Stol
  • Taken for 1 to 6 months
  • November 11, 2019

"Amitript didnt help with the neuropathy, merely drugged up, feels like a mild bad trip."

2 / 10
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20 Report
  • DeanBNE
  • Taken for 1 to 2 years
  • January 17, 2021

"Very good for my spinal damage but I can’t process it properly due to my cyp2d6 enzyme problem"

7 / 10
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1 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.