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Percocet and Constipation: What Users Say

Constipation: mentioned by 17 users (7.3%)

Based on user experiences from 234 Percocet reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 10.7%
constipation 7.3%
drowsiness 5.6%
upset stomach 3.4%
dizziness 3.0%
brain fog 2.6%
tiredness 2.6%
pain 2.1%
sweating 2.1%
withdrawal 2.1%

Reviews for Percocet

Commonly mentioned side effects
  • Ton...
  • July 9, 2021

For Chronic Pain "I've been taking Percocet 5/325, 1 and 1/2 times a day for a totally messed up lower back in constant levels of pain when moving. Can't stand up straight for 10 yrs. I also periodically get back injections and take small amounts of Methocarbamol for spasms, plus occasionally Diclofenac when extremely bad. I know for a fact I will never get addicted to the Percocet. I don't feel any 'high' or crave it ever. In fact, it makes me nauseous and constipated. Oddly enough, that little bit, spaced right, combined with other pain relief, allows me to get around pretty good, take care of grass cutting, etc. It does cut into the most severe pain, for example, Sciatica, when that flares up. And to be honest, it's safer than any other alternative, especially for those of us who never crave the feeling of the drug!! To be honest, it's overall NOT a physical feeling of well-being for me! It cuts into pain.. PERIOD!"

10 / 10
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90 Report
  • tip...
  • August 30, 2009

For Pain "To anyone who has used or will use Percocet, for the nausea, have your doctor put you on a pill called Zofran. This will help with the nausea. They give it to cancer patients for vomiting. I am a huge believer in the mental help Percocet gives as well as the pain management. Had gallbladder surgery in May 09, and after trying Vicodin, Oxycontin, Dilaudid, Ultram, Percocet was the ONLY one that helped me with the pain. Eat before taking and drink plenty of fluids. This will cause severe constipation, so a stool softener may be needed. Best medicine I have ever taken."

10 / 10
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87 Report
  • Wom...
  • Taken for less than 1 month
  • April 30, 2016

For Pain "I was prescribed this for pain following brain surgery. Take with food to prevent nausea. To avoid constipation, I took each dose with a stool softener and drank apple juice. Works good on the pain. But you do feel a little loopy on it."

8 / 10
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27 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • November 25, 2016

For Pain "I have an infected tooth with a dead nerve that needed a root canal. I got half the root canal done and need to wait for the infection to clear up. I'm taking major antibiotics, but it's still taking a while, and I'm in a lot of pain. The Percocet has helped immensely. I waited too long to take it last night and had to take a trip to the ER for morphine! The morphine was not much different than the Percocet. My problem was that I waited. I have been taking one every 6 hours, which is said on the bottle, but I think I need to do it every 5 hours. Hopefully, that's okay to do. I'm also on 800 mg of ibuprofen every 6 hours. I have not experienced any nausea, but yes, I guess I am constipated, but I have only been eating soup anyway."

10 / 10
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28 Report
  • bor...
  • Taken for less than 1 month
  • February 9, 2018

For Pain "Was prescribed generic 10/325 after wisdom teeth removal, and it made my recovery a breeze. Took one on a timer a few times a day, as advised by my surgeon, and it almost completely erased the pain. Only downside was that it wore off extremely suddenly (at least for me), so if I missed a dose, I'd be met with excruciating pain around the 6-hour mark. I had no side effects other than constipation (which was easily taken care of by an OTC laxative) and pretty extreme drowsiness. I didn't mind that, though, because I needed the rest to properly recover anyway."

10 / 10
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19 Report

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  • Kdo...
  • July 16, 2010

For Pain "I have herniated discs in my lower back from a fall. I generally don't like taking narcotic pain killers, but it gets to a certain point where I would take anything to make the pain stop. That's when I take one 5/325 Percocet. It takes 90% of my pain away when I take it with Motrin. I've tried every non-narcotic pain reliever and had no results. I tried Ultram with high hopes, but it didn't help. It's a shame that because of abuse, this medication is so frowned upon (and hard to get even if you really need it). It's so helpful for me and gets me through days that I would otherwise spend crying or in bed. The only downside is if I have to take it a couple of days in a row, I get constipated. I have no dizziness, high feeling, or nausea."

10 / 10
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26 Report
  • Wef...
  • Taken for 1 to 2 years
  • December 27, 2017

For Chronic Pain "With degenerative disc disease (DDD) and previous broken back arthritis, worn-out hip, I can't work without this med. It's what keeps me in the workforce. I get constipation, but eat fruits to counter that. I take as directed, too much clouds thought process."

10 / 10
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16 Report
  • New...
  • Taken for 6 months to 1 year
  • December 11, 2015

For Pain "I was prescribed this medication after vaginal birth, 30 hours labor, and a significant episiotomy. Medicine was a life saver. I have a very low pain tolerance and had almost no pain while taking this medicine. The cons were that I was extremely constipated and mentally was very out of it and even had some light hallucinations."

10 / 10
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19 Report
  • Me...
  • May 21, 2016

For Pain "My Rx 5/325. I had bilateral total knee replacement 12 weeks ago. Taking this totally helped me make it through this recovery period so far. I now take less than one a day and try to use ibuprofen instead. My side effects did not outweigh the benefits, but as you can see from reading the reviews, everyone has a different reaction. Mine are: constipation, so I took a laxative or suppository, slow reaction time, be extremely careful if you have to drive, if you can avoid driving, impaired/cloudy thinking, restlessness. When I go back to my desk job, I can take this during the day, but if you take it at night, you may not sleep well. I plan to continue to taper off and use only when pain level is above 5. Ibuprofen nighttime works better for sleep."

8 / 10
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18 Report
  • per...
  • February 22, 2011

For Pain "I have severe back pain and leg pain associated with sciatica. The MRI indicates a central and left herniated disk between L5-S1 and annular disc bulging at the L4-L5 level. I tried every over-the-counter pain medication and Tramadol, which did nothing. The pain in my back, left buttocks, and left calf was debilitating. I could not put on a pair of socks, let alone do any normal activity. My doctor then prescribed Percocet, and I have to say this drug is a Godsend. It actually has given me my LIFE back! I never get a 'high'-there is no feeling of euphoria-what I do get is RELIEF of my pain so that I can actually work, play, and live. Side effects: constipation. I eat bran cereal twice a day-gone. I get insomnia at night, so I take smaller amounts."

9 / 10
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19 Report
  • szq...
  • January 9, 2011

For Pain "For nerve injury, I was taking Lyrica and Vicodin - the only combination that helped (after much trial and error). Then, I had ended up with surgery (ovary removal), and the doctor prescribed Percocet 5-325. It is a wonder medicine. The first day, slightly nauseous, but that quickly went away. I now prefer the Percocet; it doesn't make me as sleepy as Vicodin. I break pills in half, spreading them throughout the day to just dial down the pain enough for me to be cheerful and productive but not zoned out. I gave it a 9 out of 10 because it does cause constipation (take Colace OTC)."

9 / 10
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13 Report
  • Mar...
  • November 27, 2015

For Pain "Prescribed this after impacted wisdom teeth extractions. Eased pain a little, but the headache, sleeplessness, constipation, jitters, and persistent nausea aren't worth it. Ibuprofen works much better without any side effects."

2 / 10
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17 Report
  • Loo...
  • Taken for 1 to 6 months
  • July 8, 2016

For Pain "My doc prescribed this for after having colitis. It dulls the pain, but for 2 months had the worst constipation (with Colace) and groin pain I ever had in my life. Went to 5 docs and had over $1500 in CT scans and ultrasounds for pain. Doc misled me and said to take it 24 hours a day. After about 2 weeks of agonizing pain, I came off it on my own. NO PAIN! Be very CAREFUL."

1 / 10
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17 Report
  • sha...
  • May 11, 2011

For Pain "I've dealt with 'undiagnosed' pain for years. I've had test after test. All I know for sure is that I have severe cramping and diarrhea, as well as joint pain. I have also suffered from anxiety and insomnia. Percocet seems to resolve all of my issues in one dose. Unfortunately, I can't get a doctor to take me seriously. The side effects seem to be limited to a warm flush and constipation, which in my case actually makes me regular."

9 / 10
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5 Report
  • Mat...
  • Taken for 10 years or more
  • October 24, 2015

For Chronic Pain "I have been on Percocet for many years, and it greatly helps my chronic pain. Without it, I wouldn't be able to walk! Only problems I have are constipation."

9 / 10
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59 Report
  • Gre...
  • September 9, 2015

For Pain "Works great for pain after knee surgery. Had a little constipation and upset stomach, but nothing too severe."

9 / 10
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31 Report
  • Fre...
  • March 8, 2012

For Pain "Excellent pain relief, without constipation associated with the use of narcotics. I didn't find that I got too drowsy from it either."

9 / 10
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7 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.