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Percocet and Nausea: What Users Say

Nausea: mentioned by 25 users (10.7%)

Based on user experiences from 234 Percocet reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 10.7%
constipation 7.3%
drowsiness 5.6%
upset stomach 3.4%
dizziness 3.0%
brain fog 2.6%
tiredness 2.6%
pain 2.1%
sweating 2.1%
withdrawal 2.1%

Reviews for Percocet

Commonly mentioned side effects
  • Pat...
  • Taken for 1 to 6 months
  • January 25, 2019

For Chronic Pain "I'm so sick on these new pills I got at Walgreens. I've been on generic Percocet for many years, and now I'm going through terrible withdrawals from this brand named MFG Camber. I agree with the others on this site - there is something wrong with this brand. I can't even get myself out of bed. It is making me shaky, nauseous, and unable to function. I'm about ready to go to a hospital if I don't start feeling better. Plus, I'm sweating like I've never sweat before. Don't get these Camber generic Percocet...you will be sick as a dog."

2 / 10
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173 Report
  • Ton...
  • July 9, 2021

For Chronic Pain "I've been taking Percocet 5/325, 1 and 1/2 times a day for a totally messed up lower back in constant levels of pain when moving. Can't stand up straight for 10 yrs. I also periodically get back injections and take small amounts of Methocarbamol for spasms, plus occasionally Diclofenac when extremely bad. I know for a fact I will never get addicted to the Percocet. I don't feel any 'high' or crave it ever. In fact, it makes me nauseous and constipated. Oddly enough, that little bit, spaced right, combined with other pain relief, allows me to get around pretty good, take care of grass cutting, etc. It does cut into the most severe pain, for example, Sciatica, when that flares up. And to be honest, it's safer than any other alternative, especially for those of us who never crave the feeling of the drug!! To be honest, it's overall NOT a physical feeling of well-being for me! It cuts into pain.. PERIOD!"

10 / 10
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90 Report
  • Ste...
  • Taken for 2 to 5 years
  • November 10, 2013

For Chronic Pain "My experience began when I was a child. I had very strange headaches, eventually diagnosed as 'ice pick migraines'. They had all the symptoms of the normal migraine you hear about, except they were so painful, my feet would draw up, my eyes would roll back, and I went almost stiff from the pain... nothing helped. When I hit my thirties, I started having issues with my spine, my pancreas, and my kidneys. Percocet is the only therapy out there that keeps me from wanting to die. My blood is thinner, and I have issues, as stated, with my pancreas and stomach, so I cannot take OTC drugs, they make me sick. Very sick. But, of course, no one believes that until they see what happens to me. It's kind of a living hell. I say if we can help, help."

9 / 10
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83 Report

Frequently asked questions

  • OLo...
  • Taken for 2 to 5 years
  • May 3, 2014

For Chronic Pain "I have many spine health issues and, as a result, experience the joys of chronic back pain. This medicine works well for moderate pain for me. I did build up a tolerance for it pretty quickly, however, which is typical for any pain medicine. Bad side effects I experienced were debilitating nausea and hot flashes when it was taken on an empty stomach. Also, the all-over 'itchies' when I first started taking the medicine. Both of these can be prevented by eating with the medicine and taking an antihistamine with it."

8 / 10
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77 Report
  • tip...
  • August 30, 2009

For Pain "To anyone who has used or will use Percocet, for the nausea, have your doctor put you on a pill called Zofran. This will help with the nausea. They give it to cancer patients for vomiting. I am a huge believer in the mental help Percocet gives as well as the pain management. Had gallbladder surgery in May 09, and after trying Vicodin, Oxycontin, Dilaudid, Ultram, Percocet was the ONLY one that helped me with the pain. Eat before taking and drink plenty of fluids. This will cause severe constipation, so a stool softener may be needed. Best medicine I have ever taken."

10 / 10
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87 Report

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  • Sar...
  • Taken for less than 1 month
  • January 8, 2016

For Pain "Ok, so you probably want to take this with food. It made me EXTREMELY nauseous when I didn't. Works well for pain. While many pain meds make a person sleepy, this one has the complete opposite effect on me. It made me extremely energetic/hyper. I had overwhelming urges to 'spring clean' the house, garage, and do things I had been putting off. The downside of that, however, is it interferes with my sleep, and I can't take it at bedtime. It's ok for daytime pain for me."

7 / 10
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48 Report
  • Wom...
  • Taken for less than 1 month
  • April 30, 2016

For Pain "I was prescribed this for pain following brain surgery. Take with food to prevent nausea. To avoid constipation, I took each dose with a stool softener and drank apple juice. Works good on the pain. But you do feel a little loopy on it."

8 / 10
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27 Report
  • Emc...
  • June 23, 2008

For Pain "I had my tonsils out a little over a week ago at the age of 30. My doctor prescribed Percocet for the pain, and although it helped my severe throat and ear pain almost instantly, it was very hard on my stomach. After 2 days, I had to stop taking it due to the amount of nausea I was experiencing. As a pain reliever, it worked wonders, just be sure to eat before you take it to avoid an upset stomach."

9 / 10
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35 Report
  • Too...
  • Taken for less than 1 month
  • April 6, 2016

For Pain "I was given Percocet recently after knee surgery. After about the 4th dose, I felt hyper, restless, nauseous, and had a very dry mouth. The worst side effect was extreme throbbing/stabbing lower back pain. I thought it was from just laying around, but whenever I didn't take the Percocet, I didn't have the lower back pain. Great for pain, but for me, it's not worth the side effects I experienced."

2 / 10
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24 Report
  • Kdo...
  • July 16, 2010

For Pain "I have herniated discs in my lower back from a fall. I generally don't like taking narcotic pain killers, but it gets to a certain point where I would take anything to make the pain stop. That's when I take one 5/325 Percocet. It takes 90% of my pain away when I take it with Motrin. I've tried every non-narcotic pain reliever and had no results. I tried Ultram with high hopes, but it didn't help. It's a shame that because of abuse, this medication is so frowned upon (and hard to get even if you really need it). It's so helpful for me and gets me through days that I would otherwise spend crying or in bed. The only downside is if I have to take it a couple of days in a row, I get constipated. I have no dizziness, high feeling, or nausea."

10 / 10
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26 Report
  • wrx...
  • January 18, 2012

For Pain "I am 19 with severe testicular pain. At first, the doctor prescribed meloxicam, which helped but made me sick. Then he put me on Vimovo, didn't help at all, and I was up all night vomiting. I told him I needed something better. At first, he was reluctant to give me Vicodin or Percocet. He later prescribed me Percocet 5/325, and man, that stuff really works. It makes you feel like yourself: no pain, no anxiety, no depression, it is a miracle for me. You must stop as the pain goes, and please only take as directed by your doctor, as it can become very addicting. A few downsides are tiredness, nausea (sometimes), and you want to talk a LOT."

9 / 10
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22 Report
  • ath...
  • March 11, 2011

For Pain "I have several chronic back conditions: herniated disc, moderate spinal stenosis, degenerative disc disease, and kyphosis. I have been taking 5/325 mg Percocet, 3-4 tabs daily for almost 2 years now. It relieves probably 80% of my pain and allows me to function. Most of the itching, sweating, nausea, etc. disappears after about a month or so of use. As most people noted, take the minimum strength needed to relieve your pain and take only as directed. At 61, I'll probably be on these the rest of my life, but at least I can function. I have found Percocet to work better than even Morphine, at least in my case. Highly recommended for chronic pain."

10 / 10
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17 Report
  • WHI...
  • August 15, 2009

For Pain "I was diagnosed with bursitis of the hip. I was in severe pain and went to see multiple doctors before even being diagnosed. I was given Vicodin, Tramadol, and an anti-inflammatory drug. None of them did the trick. After months of being in pain and continuously arguing with my doctor that those prior pills were working, he prescribed me Percocet. It works wonders. The first encounter with it made me feel really nauseous, but once I was able to lie down, it was amazing. I don't feel as though I am 'high' on it, but do feel as though I am back to my fun-loving self. My libido has increased, and I am sleeping much better. I work the graveyard shift, and it's hard enough to sleep, and this puts and keeps me asleep. Awesome, to say the least."

10 / 10
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17 Report
  • Cng...
  • October 2, 2015

For Pain "I just recently got this medicine for tooth pain. As I am going to the DDS for several issues. My RX is 5/325. I've noticed it minimizes the pain but doesn't take it away. I also am going through major nausea, sometimes vomiting. It makes me feel so tired and always thirsty. I may need to just stick with Motrin. I will talk to her about this when I go for my next appointment on Tuesday."

4 / 10
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18 Report
  • szq...
  • January 9, 2011

For Pain "For nerve injury, I was taking Lyrica and Vicodin - the only combination that helped (after much trial and error). Then, I had ended up with surgery (ovary removal), and the doctor prescribed Percocet 5-325. It is a wonder medicine. The first day, slightly nauseous, but that quickly went away. I now prefer the Percocet; it doesn't make me as sleepy as Vicodin. I break pills in half, spreading them throughout the day to just dial down the pain enough for me to be cheerful and productive but not zoned out. I gave it a 9 out of 10 because it does cause constipation (take Colace OTC)."

9 / 10
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13 Report
  • TnM...
  • September 6, 2010

For Pain "I am currently being treated for lower back pain. I am prescribed up to 4, 5 mg a day of this medicine but only need to take 2 of them a day. Until my doctor put me on this, I could not get off the couch or do much around my house. Now, I can move, and with physical therapy, I hope to zap this pain. It works great but does cause me to itch, so I take a Benadryl with it, and it does make me a little foggy. If I don't eat, I do get somewhat nauseated too."

10 / 10
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13 Report
  • Mar...
  • November 27, 2015

For Pain "Prescribed this after impacted wisdom teeth extractions. Eased pain a little, but the headache, sleeplessness, constipation, jitters, and persistent nausea aren't worth it. Ibuprofen works much better without any side effects."

2 / 10
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17 Report
  • Anonymous
  • May 11, 2009

For Pain "I use Percocet 5's as needed for shoulder instability (subluxations/dislocations). Although it works well for pain, I find that I don't like the stomach upset, lightheadedness, or nausea while on it. Eating something helps somewhat. I seem to have issues with all drugs of this type, so perhaps this is just me."

8 / 10
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12 Report
  • Ram...
  • June 26, 2009

For Pain "Took Percocet for 3 days after losing a couple of fingertips to a slamming door. It certainly helped with the pain, but made me nauseous, dizzy, and drowsy. I had to lie down most of the time I took this drug. I got off it as soon as I could."

6 / 10
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12 Report
  • Anonymous
  • May 20, 2009

For Pain "I take Percocet, and it has done wonders for me. Before, I was unable to stand for more than 10 minutes due to chronic back pain, and now I do a normal workload without taking frequent breaks. It works great but does make me nauseated at times."

9 / 10
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9 Report
  • SoF...
  • January 21, 2009

"This is a wonder drug for me. I am allergic to both codeine and hydrocodone, and yesterday I had to go to the ER for an extremely infected hair follicle. I was in such horrible pain my blood pressure was through the roof. The doctor gave me a Percocet before he applied lidocaine to my follicle. I didn't feel a thing. Not even when he said the lidocaine would hurt. He sent me home with a 5 mg prescription. It did make me somewhat nauseated. I took a Phenergan with it and was able to rest. I really recommend this medicine."

10 / 10
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1 Report
  • TJC...
  • Taken for 5 to 10 years
  • November 20, 2013

For Chronic Pain "Doesn't control pain for long enough period of time. Decreases pain from 9 to 7 for 2 hours, then pain starts to increase again. Also causes nausea and dry mouth."

8 / 10
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70 Report
  • Kid...
  • February 25, 2014

For Pain "Given this for kidney stones. Takes away the pain, helps you relax. I experience a little bit of nausea, but not severe."

8 / 10
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35 Report
  • Anonymous
  • June 16, 2009

For Pain "I used this after my throat surgery. It killed the pain really well, but it made me nauseous and dizzy."

10 / 10
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9 Report
  • aha...
  • July 2, 2015

For Pain "This made me extremely nauseated. I was not even able to keep it down, let alone benefit from any pain relief."

1 / 10
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14 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.