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Percocet and Upset Stomach: What Users Say

Upset stomach: mentioned by 8 users (3.4%)

Based on user experiences from 234 Percocet reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

nausea 10.7%
constipation 7.3%
drowsiness 5.6%
upset stomach 3.4%
dizziness 3.0%
brain fog 2.6%
tiredness 2.6%
pain 2.1%
sweating 2.1%
withdrawal 2.1%

Reviews for Percocet

Commonly mentioned side effects
  • Ste...
  • Taken for 2 to 5 years
  • November 10, 2013

For Chronic Pain "My experience began when I was a child. I had very strange headaches, eventually diagnosed as 'ice pick migraines'. They had all the symptoms of the normal migraine you hear about, except they were so painful, my feet would draw up, my eyes would roll back, and I went almost stiff from the pain... nothing helped. When I hit my thirties, I started having issues with my spine, my pancreas, and my kidneys. Percocet is the only therapy out there that keeps me from wanting to die. My blood is thinner, and I have issues, as stated, with my pancreas and stomach, so I cannot take OTC drugs, they make me sick. Very sick. But, of course, no one believes that until they see what happens to me. It's kind of a living hell. I say if we can help, help."

9 / 10
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  • bad...
  • Taken for 10 years or more
  • April 22, 2016

For Chronic Pain "I have been on Percocet for 16 years. I started out with low-grade Vicodin. I have taken the name brand with no problems. When they switched me to generic, I had some problems with the way they affected me, they didn't seem to work as well. But when they switched the generic brand to another generic brand, I had an upset stomach and a very bad rash. Sometimes you have to take the name brand instead of generics, even though they say the generics are the same, they are not. I could tell the difference, but I have tried OxyContin and had a very bad itching and a rash, so I guess I'm stuck on them. I have days I take more than I'm supposed to in the morning and do without later, but the pain is so bad it's almost suicidal."

7 / 10
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66 Report
  • lov...
  • October 30, 2013

For Pain "I have really bad back pain, and at such a young age, I take Percocet four times a day, and it allows me to sleep and work, whereas other medications just made my stomach upset. I would rate it a 9 for the relief it gives you. I honestly felt like I could not function anymore, I was in so much pain, and now I enjoy walking. I don't have to stop every 10 minutes to catch my breath from my pain."

9 / 10
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69 Report

Frequently asked questions

  • Emc...
  • June 23, 2008

For Pain "I had my tonsils out a little over a week ago at the age of 30. My doctor prescribed Percocet for the pain, and although it helped my severe throat and ear pain almost instantly, it was very hard on my stomach. After 2 days, I had to stop taking it due to the amount of nausea I was experiencing. As a pain reliever, it worked wonders, just be sure to eat before you take it to avoid an upset stomach."

9 / 10
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35 Report
  • Anonymous
  • May 11, 2009

For Pain "I use Percocet 5's as needed for shoulder instability (subluxations/dislocations). Although it works well for pain, I find that I don't like the stomach upset, lightheadedness, or nausea while on it. Eating something helps somewhat. I seem to have issues with all drugs of this type, so perhaps this is just me."

8 / 10
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12 Report

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  • Ame...
  • December 10, 2009

For Pain "My husband had his wisdom teeth surgically removed a few days ago. His doctor prescribed this medicine for the pain, and he says it really helps him. They were giving him this in the hospital, and he went from a 7 to a 2. I say it does what it is supposed to do very well. He hasn't had any upset stomach problems yet, but it does put him to sleep."

8 / 10
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4 Report
  • Ban...
  • July 28, 2009

For Pain "I had rotator cuff surgery, and I was prescribed Percocet after telling the doctor that I have a sensitive stomach to most medications. The medicine took the pain away, but I only take half a pill of the 5 mg, and my stomach gets so upset and I try not to vomit. I can't get in a car without getting carsick. The doctor has now prescribed me Darvocet, let's hope this works better."

3 / 10
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4 Report
  • Gre...
  • September 9, 2015

For Pain "Works great for pain after knee surgery. Had a little constipation and upset stomach, but nothing too severe."

9 / 10
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31 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.