Generic name: Pantoprazole Injection [ pan-TOE-pra-zole ]
Drug class: Proton pump inhibitors
Medically reviewed by Drugs.com. Last updated on Apr 16, 2023.
Uses of Protonix I.V.:
- It is used to treat gastroesophageal reflux disease (GERD; acid reflux).
- It is used to treat syndromes caused by lots of stomach acid.
- It may be given to you for other reasons. Talk with the doctor.
What do I need to tell my doctor BEFORE I take Protonix I.V.?
- If you have an allergy to pantoprazole or any other part of Protonix I.V. (pantoprazole injection).
- If you are allergic to Protonix I.V. (pantoprazole injection); any part of Protonix I.V. (pantoprazole injection); or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
- If you are taking any of these drugs: Atazanavir, nelfinavir, or rilpivirine.
This is not a list of all drugs or health problems that interact with Protonix I.V. (pantoprazole injection).
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Protonix I.V. (pantoprazole injection) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Protonix I.V.?
- Tell all of your health care providers that you take Protonix I.V. (pantoprazole injection). This includes your doctors, nurses, pharmacists, and dentists.
- Do not take Protonix I.V. (pantoprazole injection) for longer than you were told by your doctor.
- This medicine may affect certain lab tests. Tell all of your health care providers and lab workers that you take Protonix I.V. (pantoprazole injection).
- Call your doctor if you have throat pain, chest pain, very bad belly pain, trouble swallowing, or signs of a bleeding ulcer like black, tarry, or bloody stools, throwing up blood, or throw up that looks like coffee grounds. These may be signs of a worse health problem.
- This medicine may raise the chance of hip, spine, and wrist fractures in people with weak bones (osteoporosis). The chance may be higher if you take Protonix I.V. (pantoprazole injection) in high doses or for longer than a year, or if you are older than 50 years old.
- Use care if you have risks for soft, brittle bones (osteoporosis). Some of these risks include drinking alcohol, smoking, taking steroids, taking drugs to treat seizures, or having family members with osteoporosis. Talk with your doctor about your risks of osteoporosis.
- Rarely, low magnesium levels have happened in people taking drugs like this one for at least 3 months. Most of the time, this happened after 1 year of treatment. You will need to have blood work if you take Protonix I.V. (pantoprazole injection) for a long time or with certain other drugs.
- Long-term treatment (for instance longer than 3 years) with drugs like this one has rarely caused low vitamin B-12 levels. Talk with the doctor.
- You may need to take zinc while you take Protonix I.V. (pantoprazole injection). Talk with your doctor.
- Tell your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. You will need to talk about the benefits and risks to you and the baby.
How is this medicine (Protonix I.V.) best taken?
Use Protonix I.V. (pantoprazole injection) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- This medicine is given as a shot into a vein or into a vein nonstop for a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of low magnesium levels like mood changes, muscle pain or weakness, muscle cramps or spasms, seizures, shakiness, not hungry, very bad upset stomach or throwing up, or a heartbeat that does not feel normal.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Bone pain.
- Lupus has happened with Protonix I.V. (pantoprazole injection), as well as lupus that has gotten worse in people who already have it. Tell your doctor if you have lupus. Call your doctor right away if you have signs of lupus like a rash on the cheeks or other body parts, sunburn easy, muscle or joint pain, chest pain or shortness of breath, or swelling in the arms or legs.
- Irritation where the shot is given.
- This medicine may raise the chance of a severe form of diarrhea called C diff-associated diarrhea (CDAD). Call your doctor right away if you have stomach pain or cramps, very loose or watery stools, or bloody stools. Do not try to treat diarrhea without first checking with your doctor.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
What are some other side effects of Protonix I.V.?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Stomach pain or diarrhea.
- Upset stomach or throwing up.
- Joint pain.
- Signs of a common cold.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Protonix I.V.?
- If you need to store Protonix I.V. (pantoprazole injection) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- This medicine comes with an extra patient fact sheet called a Medication Guide. Read it with care. Read it again each time Protonix I.V. (pantoprazole injection) is refilled. If you have any questions about Protonix I.V. (pantoprazole injection), please talk with the doctor, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Frequently asked questions
- Pantoprazole vs. omeprazole: What's the difference between them?
- Can you take pantoprazole 40 mg twice a day?
- How long can I take pantoprazole?
- Does pantoprazole cause bloating?
More about Protonix IV (pantoprazole)
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- Drug class: proton pump inhibitors
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