Generic Name: olsalazine (ol-SAL-a-zeen)
Brand Name: Dipentum
Olsalazine is used for:
Controlling symptoms of ulcerative colitis in patients who cannot take sulfasalazine.
Olsalazine is a salicylate. It works by reducing inflammation of the colon by possibly preventing the production of substances that cause this inflammation.
Do NOT use olsalazine if:
- you are allergic to any ingredient in olsalazine
- you are allergic to aspirin or medications similar to aspirin (eg, salicylates)
- you have received the varicella (chickenpox) vaccine within the past 6 weeks
Contact your doctor or health care provider right away if any of these apply to you.
Before using olsalazine:
Some medical conditions may interact with olsalazine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have kidney or liver problems, asthma, or severe allergies
- if you have or recently had a viral infection (eg, flu, chickenpox)
Some MEDICINES MAY INTERACT with olsalazine. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Thiopurines (eg, azathioprine, mercaptopurine, thioguanine) because the risk of bone marrow toxicity may be increased
- Anticoagulants (eg, warfarin) or heparin because the risk of their side effects may be increased by olsalazine
This may not be a complete list of all interactions that may occur. Ask your health care provider if olsalazine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use olsalazine:
Use olsalazine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take olsalazine by mouth with food.
- Take olsalazine in evenly divided doses.
- Continue taking olsalazine for the full course of treatment. Keep taking it even if you feel better in a few days.
- If you miss a dose of olsalazine, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. If more than one dose is missed, contact your doctor or pharmacist.
Ask your health care provider any questions you may have about how to use olsalazine.
Important safety information:
- Olsalazine may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use olsalazine with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- If diarrhea occurs while taking olsalazine, contact your health care provider.
- If your symptoms do not improve or if they worsen after you start using olsalazine, check with your doctor.
- Salicylates have been linked to a serious illness called Reye syndrome. Check with your doctor before you give olsalazine to a child or teenager who has the flu, chickenpox, or a viral infection, or has recently had such an illness. Contact your doctor with any questions or concerns.
- Olsalazine should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using olsalazine while you are pregnant. Olsalazine is found in breast milk. Do not breast-feed while taking olsalazine.
Possible side effects of olsalazine:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Diarrhea; joint pain; nausea; stomach pain or cramps.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in the amount of urine; chest pain; dark urine; fast or irregular heartbeat; pale stools; severe stomach pain; trouble urinating; unusual bruising or bleeding; yellowing of the eyes or skin.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include nausea, vomiting, or diarrhea.Proper storage of olsalazine:
Store olsalazine in a tightly closed container at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep olsalazine out of the reach of children and away from pets.
- If you have any questions about olsalazine, please talk with your doctor, pharmacist, or other health care provider.
- Olsalazine is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take olsalazine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about olsalazine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to olsalazine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using olsalazine.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about olsalazine
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
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- Drug class: 5-aminosalicylates
Other brands: Dipentum