olsalazine (Oral route)
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Gastrointestinal Agent
Chemical Class: Salicylate, Non-Aspirin
Uses For olsalazine
Olsalazine is used in patients who have had ulcerative colitis to prevent the condition from occurring again. It works inside the bowel by helping to reduce inflammation and other symptoms of the disease.
Olsalazine is available only with your doctor's prescription.
Before Using olsalazine
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For olsalazine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to olsalazine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Studies on olsalazine have been done only in adult patients, and there is no specific information comparing use of olsalazine in children with use in other age groups.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no specific information comparing use of olsalazine in the elderly with use in other age groups, olsalazine is not expected to cause different side effects or problems in older people than it does in younger adults.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using olsalazine.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking olsalazine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using olsalazine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Amtolmetin Guacil
- Flufenamic Acid
- Mefenamic Acid
- Niflumic Acid
- Nimesulide Beta Cyclodextrin
- Tiaprofenic Acid
- Tolfenamic Acid
- Varicella Virus Vaccine
Using olsalazine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of olsalazine. Make sure you tell your doctor if you have any other medical problems, especially:
- Kidney disease—The use of olsalazine may cause further damage to the kidneys
Proper Use of olsalazine
Olsalazine is best taken with food, to lessen stomach upset. If stomach or intestinal problems continue or are bothersome, check with your doctor.
Keep taking olsalazine for the full time of treatment , even if you begin to feel better after a few days. Do not miss any doses.
The dose of olsalazine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of olsalazine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (capsules):
- To prevent ulcerative colitis from occurring again:
- Adults and teenagers—500 milligrams (mg) two times a day.
- Children—Use and dose must be determined by your doctor.
- To prevent ulcerative colitis from occurring again:
If you miss a dose of olsalazine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Precautions While Using olsalazine
It is very important that your doctor check your progress at regular visits, especially if you will be taking olsalazine for a long time.
olsalazine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor as soon as possible if any of the following side effects occur:Rare
- Back or stomach pain (severe)
- bloody diarrhea
- fast heartbeat
- nausea or vomiting
- skin rash
- swelling of the stomach
- yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Abdominal or stomach pain or upset
- loss of appetite
- Aching joints and muscles
- anxiety or depression
- dizziness or drowsiness
- trouble in sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
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More about olsalazine
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
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- Drug class: 5-aminosalicylates
Other brands: Dipentum