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Desloratadine and Pseudoephedrine

Generic Name: Desloratadine and Pseudoephedrine (des lor AT a deen & soo doe e FED rin)
Brand Name: Clarinex-D 12 Hour

Medically reviewed on September 5, 2018

Uses of Desloratadine and Pseudoephedrine:

  • It is used to treat nose stuffiness.
  • It is used to ease allergy signs.

What do I need to tell my doctor BEFORE I take Desloratadine and Pseudoephedrine?

  • If you have an allergy to desloratadine, loratadine, pseudoephedrine, or any other part of desloratadine and pseudoephedrine.
  • If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • If you have any of these health problems: Glaucoma, heart disease, high blood pressure, or trouble passing urine.
  • If you have any of these health problems: Kidney disease or liver disease.
  • If you have taken certain drugs used for low mood (depression) like isocarboxazid, phenelzine, or tranylcypromine or drugs used for Parkinson's disease like selegiline or rasagiline in the last 14 days. Taking desloratadine and pseudoephedrine within 14 days of those drugs can cause very bad high blood pressure.
  • If you are breast-feeding or plan to breast-feed.

This is not a list of all drugs or health problems that interact with desloratadine and pseudoephedrine.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take desloratadine and pseudoephedrine with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

What are some things I need to know or do while I take Desloratadine and Pseudoephedrine?

  • Tell all of your health care providers that you take desloratadine and pseudoephedrine. This includes your doctors, nurses, pharmacists, and dentists.
  • Do not take more than what your doctor told you to take. Taking more than you are told may raise your chance of very bad side effects.
  • Do not take desloratadine and pseudoephedrine for longer than you were told by your doctor.
  • This medicine is not approved for use in children younger than 12 years old. Talk with the doctor.
  • If you are 65 or older, use desloratadine and pseudoephedrine with care. You could have more side effects.
  • Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using desloratadine and pseudoephedrine while you are pregnant.

How is this medicine (Desloratadine and Pseudoephedrine) best taken?

Use desloratadine and pseudoephedrine as ordered by your doctor. Read all information given to you. Follow all instructions closely.

  • Take with or without food. Take with food if it causes an upset stomach.
  • Swallow whole. Do not chew, break, or crush.
  • If you have trouble swallowing, talk with your doctor.

What do I do if I miss a dose?

  • If you take desloratadine and pseudoephedrine on a regular basis, take a missed dose as soon as you think about it.
  • If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
  • Do not take 2 doses at the same time or extra doses.
  • Many times desloratadine and pseudoephedrine is taken on an as needed basis. Do not take more often than told by the doctor.

See also: Dosage Information (in more detail)

What are some side effects that I need to call my doctor about right away?

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

  • Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
  • Many small pimples.
  • Fever.
  • Trouble passing urine.
  • A fast heartbeat.
  • A heartbeat that does not feel normal.
  • Very bad dizziness or passing out.
  • Shortness of breath.
  • Shakiness.
  • Seizures.
  • Change in eyesight.

What are some other side effects of Desloratadine and Pseudoephedrine?

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

  • Dizziness.
  • Feeling nervous and excitable.
  • Not able to sleep.
  • Feeling sleepy.
  • Dry mouth.
  • Headache.
  • Not hungry.
  • Sore throat.
  • Upset stomach.
  • Feeling tired or weak.
  • Restlessness.

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

See also: Side effects (in more detail)

If OVERDOSE is suspected:

If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

How do I store and/or throw out Desloratadine and Pseudoephedrine?

  • Store at room temperature.
  • Protect from heat.
  • Protect from light.
  • Store in a dry place. Do not store in a bathroom.
  • Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
  • Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Consumer information use

  • If your symptoms or health problems do not get better or if they become worse, call your doctor.
  • Do not share your drugs with others and do not take anyone else's drugs.
  • Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
  • Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
  • Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about desloratadine and pseudoephedrine, please talk with your doctor, nurse, pharmacist, or other health care provider.
  • If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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