Generic Name: methsuximide (meth-SUX-i-mide)
Brand Name: Celontin
Celontin is used for:
Treating certain types of seizures when other medicines have failed.
Celontin is an anticonvulsant. It works by reducing abnormal nerve transmission in the brain, which helps decrease seizures.
Do NOT use Celontin if:
- you are allergic to any ingredient in Celontin or to other succinimides (eg, ethosuximide)
Contact your doctor or health care provider right away if any of these apply to you.
Before using Celontin:
Some medical conditions may interact with Celontin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have the blood disease porphyria, liver or kidney problems, or lupus
- if you have a history of mental or mood problems (eg, depression), or suicidal thoughts or attempts
Some MEDICINES MAY INTERACT with Celontin. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Barbiturates (eg, phenobarbital) or hydantoins (eg, phenytoin) because the side effects of Celontin may be increased
- Lamotrigine because its effectiveness may be decreased by Celontin
This may not be a complete list of all interactions that may occur. Ask your health care provider if Celontin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Celontin:
Use Celontin as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Celontin comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Celontin refilled.
- Celontin may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
- Do not take capsules that are not full or in which the contents have melted.
- Do not suddenly stop taking Celontin. You may have an increased risk of side effects (eg, seizures). If you need to stop Celontin or add a new medicine, your doctor will gradually lower your dose.
- If you miss a dose of Celontin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Celontin.
Important safety information:
- Celontin may cause dizziness, drowsiness, or blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Celontin. Using Celontin alone, with certain other medicines, or with alcohol may lessen your ability to drive or perform other potentially dangerous tasks.
- Do NOT take more than the recommended dose without checking with your doctor.
- Patients who take Celontin may be at increased risk for suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take Celontin closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual changes in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Lab tests, including complete blood cell counts or liver or kidney function tests, may be performed while you use Celontin. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- PREGNANCY and BREAST-FEEDING: Celontin may cause harm to the fetus. If you think you may be pregnant, discuss with your doctor the benefits and risks of using Celontin during pregnancy. It is unknown if Celontin is excreted in breast milk. If you are or will be breast-feeding while taking Celontin, check with your doctor to discuss the risk to your baby.
If you suddenly stop taking Celontin, you may experience WITHDRAWAL symptoms, including seizures.
Possible side effects of Celontin:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; diarrhea; dizziness; drowsiness; headache; loss of appetite; loss of coordination; nausea; stomach pain; trouble sleeping; vomiting; weight loss.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); aggressive behavior; bloody urine; blurred vision or other vision changes; clumsiness; confusion; dark urine; fever, chills, or persistent sore throat; hallucinations; new or worsening mood or mental changes (eg, anxiety, depression, nervousness, restlessness, irritability, panic attacks, behavior changes, suicidal thoughts or attempts); new or worsening seizures; red, swollen, peeling, or blistered skin; sensitivity to light; yellowing of the skin or eyes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include coma; nausea; slow breathing; vomiting.Proper storage of Celontin:
Store Celontin at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from light, moisture, and excessive heat (104 degrees F [40 degrees C]). Keep Celontin out of the reach of children and away from pets.
- If you have any questions about Celontin, please talk with your doctor, pharmacist, or other health care provider.
- Celontin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Celontin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Celontin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Celontin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Celontin.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Celontin (methsuximide)
- Side Effects
- During Pregnancy
- Dosage Information
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- Drug Interactions
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- Drug class: succinimide anticonvulsants