Generic name: amlodipine and olmesartan [ am-LOE-de-peen-ol-me-SAR-tan ]
Drug class: Angiotensin II inhibitors with calcium channel blockers
What is Azor?
Amlodipine is a calcium channel blocker. It works by relaxing the muscles of your heart and blood vessels.
Olmesartan is an angiotensin II receptor antagonist (sometimes called an ARB). Olmesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.
Azor is used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.
Do not use Azor if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away.
If you have diabetes, do not use Azor together with any medication that contains aliskiren (such as Amturnide, Tekturna, Tekamlo).
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Call your doctor at once if you have swelling in your hands or feet, rapid weight gain, pounding heartbeats or fluttering in your chest, urinating less than usual, jaundice (yellowing of the skin or eyes), chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling, or if you feel like you might pass out.
Before taking this medicine
You should not use Azor if you are allergic to amlodipine or olmesartan.
If you have diabetes, do not use Azor together with any medication that contains aliskiren (a blood pressure medicine).
You may also need to avoid taking amlodipine and olmesartan with aliskiren if you have kidney disease.
To make sure Azor is safe for you, tell your doctor if you have:
high levels of potassium in your blood;
if you are on a low-salt diet;
if you are 75 years or older; or
if you recently had a heart attack.
Do not use if you are pregnant. If you become pregnant, stop taking this medicine and tell your doctor right away. Olmesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.
You should not breastfeed while using this medicine.
Azor is not approved for use by anyone younger than 18 years old.
How should I take Azor?
Take Azor exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose.
You may take Azor with or without food.
Your blood pressure will need to be checked often. Your kidney function may also need to be checked.
Certain conditions can cause your blood pressure to get too low. This includes vomiting, diarrhea, or heavy sweating. Call your doctor if you are sick with vomiting or diarrhea.
If you need surgery, tell the surgeon ahead of time that you are using Azor.
Keep using Azor as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.
Store at room temperature away from moisture and heat.
Usual Adult Dose for Hypertension:
Initial dose: Amlodipine 5 mg-Olmesartan 20 mg orally once a day; may increase dose after 1 to 2 weeks of therapy.
Maximum dose: Amlodipine 10 mg-Olmesartan 40 mg orally once a day
-Substitution therapy for patients maintained on the individual components separately or for patients not adequately controlled with one of the components or a component within the same antihypertensive class.
-Initial therapy in patients who are likely to need more than 1 antihypertensive agent to control blood pressure.
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What to avoid
If you also take colesevelam, avoid taking it for at least 4 hours after you have taken Azor.
Avoid driving or hazardous activity until you know how this medicine will affect you. Your reactions could be impaired. Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.
Do not use potassium supplements or salt substitutes, unless your doctor has told you to.
Azor side effects
Get emergency medical help if you have signs of an allergic reaction to Azor: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
When you first start taking this medicine, you may have new or worsening chest pain (angina), or you could have a heart attack. Seek emergency medical attention or call your doctor right away if you have symptoms such as: chest pain or pressure, pain spreading to your jaw or shoulder, nausea, sweating.
Call your doctor at once if you have:
new or worsening chest pain;
swelling in your hands or feet, rapid weight gain;
severe or ongoing diarrhea with weight loss;
pounding heartbeats or fluttering in your chest;
a light-headed feeling, like you might pass out; or
high potassium level - nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement.
Common Azor side effects include:
flushing (warmth, redness, or tingly feeling); or
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Azor?
Sometimes it is not safe to use certain medications at the same time. Some drugs can affect your blood levels of other drugs you take, which may increase side effects or make the medications less effective.
If you also take colesevelam, take it 4 hours after you take Azor.
Tell your doctor about all your other medicines, especially:
This list is not complete. Other drugs may interact with amlodipine and olmesartan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
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Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Azor only for the indication prescribed.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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