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Active substance(s): METHENAMINE HIPPURATE

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Patient Information Leaflet
243 mini

Hiprex 1g tablets
Methenamine hippurate
Read all of this leaflet carefully before you start taking this medicine because it c­ ontains
important information for you.
Always take this medicine exactly as described in this leaflet or as your doctor, pharmacist or nurse has
told you.
• Keep this leaflet. You may need to read it again.
• If you have any further questions, ask your doctor or pharmacist.
• This medicine has been prescribed for you only. Do not pass it on to others. It may harm them, even
if their signs of illness are the same as yours.
• If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects
not listed in this leaflet. See section 4.
What is in this leaflet:
1. What Hiprex is and what it is used for
4. Possible side effects
2. What you need to know before you take Hiprex
5. How to store Hiprex
3. How to take Hiprex
6. Contents of the pack and other information.

1. What Hiprex is and what it is used for
Hiprex contains the active substance methenamine hippurate and belongs to a group of medicines
called anti-bacterials. These work by killing many different types of bacteria which cause infections.
Hiprex is used to treat infections of the urinary tract and stop them from coming back. The urinary tract
is a collective name for the parts of the body that produce, store and transport urine. These include the
kidney, bladder and tubes called the ureter and urethra. It is also used to avoid urinary tract infections
in patients with catheters from their bladders (a tube that helps with incontinence) and in people
undergoing certain medical procedures.

2. What you need to know before you take Hiprex
Do not use Hiprex if:
• You are allergic to methenamine hippurate or any of the other ingredients of this medicine (listed in
section 6)
• You are taking antibiotic medicines called sulphonamides. These can damage your k­ idneys when
taken at the same time as Hiprex
• You are severely dehydrated
• You have serious problems with your kidneys
• You have problems with your liver
• You have gout
• You have a condition called metabolic acidosis (a chemical imbalance in the blood).
If any of the above applies to you, talk to your doctor or pharmacist.
Warnings and precautions
Check with your doctor before taking Hiprex if:
• You have any kinds of problems with your kidneys.
Tell your doctor if you are taking any of the following medicines:
• Medicines to make your urine less acidic such as potassium citrate and acetazolamide.
These can stop Hiprex working properly
• Any other medicines, including medicines obtained without a prescription.
Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask
your doctor or pharmacist for advice before taking this medicine.

3. How to take Hiprex
Always take Hiprex exactly as your doctor has told you. You should check with your doctor or
­pharmacist if you are not sure.
Your doctor will choose the dose that is right for you. Your dose will be shown clearly on the
label that your pharmacist puts on your medicine. If it does not, or you are not sure, ask your
doctor or pharmacist.

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The recommended dose is one tablet twice a day.
If you have a catheter your doctor may increase your dose to one tablet three times a day.
Use in children
Not for children aged under 6.
Children aged 6 – 12 years the recommended dose is half a tablet (500mg) twice a day.
Method of administration
The tablets can be broken in half. If you find it particularly difficult to swallow them, the tablets may be
crushed and taken with a drink of milk or fruit juice.
If you take more Hiprex than you should
If you accidentally take more Hiprex than you should you might be sick or see blood in your urine.
Drink plenty of water and immediately go to the nearest hospital casualty department or your doctor.
Your doctor may give you another medicine to stop you being sick.
If you forget to take Hiprex
Do not take a double dose to make up for a missed dose. Simply take your next dose as planned.
If you stop taking Hiprex
Your doctor will tell you how long to take your medicine for. Do not stop taking Hiprex w
­ ithout first
­talking to your doctor.
If you have further questions on the use of this medicine, ask your doctor or pharmacist.

4. Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
You may experience the following:
Uncommon: may affect up to 1 in 100 people
• Rashes
• Itching
• Stomach irritation
• Bladder irritation usually seen as a burning sensation and pain on urinating.
Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This
includes any possible side effects not listed in this leaflet. You can also report side effects directly via
the Yellow Card Scheme at:
By reporting side effects you can help provide more information on the safety of this medicine.

5. How to store Hiprex
Keep out of the reach and sight of children.
Do not use Hiprex after the expiry date which is stated on the bottle. The expiry date refers to the last
day of that month.
Store Hiprex below 30 °C, with the bottle lid tightly closed in its original carton.
Medicines should not be disposed of via wastewater or household waste. Return any m
­ edicine you no
longer need to your pharmacist.

6. Contents of the pack and other information
What Hiprex contains
The active substance is methenamine hippurate. Each tablet contains 1 gram.
The other ingredients are magnesium stearate (E572), povidone and colloidal anhydrous silica.
What Hiprex looks like
Each tablet is white, oblong shaped with breakline and is marked “HX” on one side and “3M” on the
other. Hiprex comes in a glass bottle which contains 60 tablets.
Marketing Authorisation Holder:
Meda Pharmaceuticals Ltd, Skyway House, Parsonage Road, Takeley, Bishop’s Stortford,
CM22 6PU, United Kingdom.
3M Health Care Ltd, Loughborough, Leicestershire, LE11 1EP, United Kingdom.
This leaflet was last revised on March 2015

If this leaflet is difficult to see or read and you would like it in a different format,
please contact Meda Pharmaceuticals, Skyway House, Parsonage Road,
Takeley, Bishop’s Stortford, CM22 6PU, United Kingdom.
6204 2459 4
Hiprex is a trademark of MEDA AB.
The Triangle Logo on the packaging is a trademark
of 3M and is used under license.

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