Hiprex Side Effects

Generic Name: methenamine

Note: This page contains information about the side effects of methenamine. Some of the dosage forms included on this document may not apply to the brand name Hiprex.

For the Consumer

Applies to methenamine: oral suspension, oral tablet, oral tablet enteric coated

In addition to its needed effects, some unwanted effects may be caused by methenamine (the active ingredient contained in Hiprex). In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking methenamine:

• Skin rash

• Blood in urine
• lower back pain
• pain or burning while urinating

Minor Side Effects

Some of the side effects that can occur with methenamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

• Nausea and vomiting

For Healthcare Professionals

Applies to methenamine: compounding powder, oral suspension, oral tablet

General

This drug was generally well tolerated. Minor side effects have been reported in less than 3.5% of patients and were reversible when the drug was stopped.^[Ref]

Dermatologic

Uncommon (0.1% to 1%): Rash, pruritus
Frequency not reported: Generalized skin rash^[Ref]

Gastrointestinal

Uncommon (0.1% to 1%): Gastric irritation
Frequency not reported: Nausea, vomiting, upset stomach, stomatitis, gastrointestinal disturbances, diarrhea, abdominal cramping^[Ref]

Genitourinary

High doses have been associated with albuminuria, gross hematuria, bladder irritation, and painful/frequent micturition.^[Ref]

Uncommon (0.1% to 1%): Bladder irritation
Frequency not reported: Dysuria, hematuria, urinary frequency, albuminuria^[Ref]

Hepatic

Frequency not reported: Elevated AST, elevated ALT^[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions^[Ref]

Metabolic

Frequency not reported: Anorexia

Ocular

Frequency not reported: Anterior uveitis^[Ref]

Not all side effects for Hiprex may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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