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Zemuron Side Effects

Generic Name: rocuronium

Note: This document contains side effect information about rocuronium. Some of the dosage forms listed on this page may not apply to the brand name Zemuron.

For the Consumer

Applies to rocuronium: intravenous solution

Along with its needed effects, rocuronium (the active ingredient contained in Zemuron) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking rocuronium:

  • Cough
  • difficulty with breathing
  • dizziness
  • fainting
  • fast, slow, or irregular heartbeat
  • noisy breathing
  • swelling at the injection site
  • tightness in the chest
Incidence not known
  • Difficulty with swallowing
  • hives, itching, or skin rash
  • muscular pain, tenderness, wasting, or weakness
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to rocuronium: intravenous solution


Uncommon (0.1% to 1%): Arrhythmia, abnormal electrocardiogram, tachycardia
Rare (0.01% to 0.1%): Hypotension, hypertension
Very rare (less than 0.01%): Circulatory collapse and shock, flushing[Ref]


Rare (0.01% to 0.1%): Injection site edema, pruritus
Very rare (less than 0.01%): Angioneurotic edema, urticaria, rash, erythematous rash[Ref]


Uncommon (0.1% to 1%): Nausea, vomiting[Ref]


Very rare (less than 0.01%): Hypersensitivity, anaphylactic reaction, anaphylactoid reaction, anaphylactic shock, anaphylactoid shock[Ref]


Uncommon (0.1% to 1%): Asthma (bronchospasm, wheezing, or rhonchi), hiccup
Very rare (less than 0.01%): Bronchospasm
Postmarketing reports: Increased pulmonary vascular resistance[Ref]


Rare (less than 0.1%): Injection site pain, injection site reaction[Ref]


Rare (less than 0.1%): Prolonged neuromuscular block
Very rare (less than 0.01%): Muscular weakness
Frequency not reported: Residual paralysis, myopathy[Ref]

Nervous system

Very rare (less than 0.01%): Flaccid paralysis[Ref]


Uncommon (0.1% to 1%): Drug ineffective, drug effect/therapeutic response decreased, drug effect/therapeutic response increased
Frequency not reported: Malignant hyperthermia[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Zemuron (rocuronium)." Organon, West Orange, NJ.

3. Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL:" ([2006]):

Some side effects of Zemuron may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.