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Yosprala Side Effects

Generic name: aspirin / omeprazole

Medically reviewed by Drugs.com. Last updated on Jul 7, 2023.

Note: This document provides detailed information about Yosprala Side Effects associated with aspirin / omeprazole. Some dosage forms listed on this page may not apply specifically to the brand name Yosprala.

Applies to aspirin / omeprazole: oral tablet delayed release.

Serious side effects of Yosprala

Along with its needed effects, aspirin / omeprazole may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking aspirin / omeprazole:

More common side effects

  • burning feeling in the chest or stomach
  • indigestion
  • stomach upset or tenderness

Less common side effects

  • black, tarry stools
  • chest pain
  • diarrhea
  • vomiting of blood or material that looks like coffee grounds

Incidence not known

  • blistering, peeling, or loosening of the skin
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • blurred vision
  • chest tightness
  • chills
  • confusion
  • constipation
  • continuing vomiting
  • cough
  • darkened urine
  • decreased frequency or amount of urine
  • difficulty breathing
  • difficulty swallowing
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • general feeling of discomfort or illness
  • hair loss
  • headache
  • heartburn
  • hives, itching, skin rash
  • increased thirst
  • indigestion
  • joint or muscle pain
  • loss of appetite
  • lower back or side pain
  • mood or mental changes
  • muscle or joint pain
  • muscle spasms (tetany) or twitching
  • nausea
  • nervousness
  • nosebleed
  • numbness or tingling in the hands, feet, or lips
  • pain or swelling in the arms or legs without any injury
  • painful or difficult urination
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid weight gain
  • red skin lesions, often with a purple center
  • red, irritated eyes
  • seizures
  • severe stomach cramps and pain
  • slow heartbeat
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • stomach pain, cramping, tenderness, or burning
  • swelling of the face, fingers, or lower legs
  • swollen glands
  • trembling
  • trouble breathing
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss
  • vomiting
  • watery and severe diarrhea, which may also be bloody
  • weakness or heaviness of the legs
  • weight gain
  • yellow eyes or skin

Other side effects of Yosprala

Some side effects of aspirin / omeprazole may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

  • bad unusual or unpleasant (after) taste
  • belching
  • burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • change in taste
  • decreased interest in sexual intercourse
  • double vision
  • heartburn
  • inability to have or keep an erection
  • increased sensitivity of the skin to sunlight
  • loss in sexual ability, desire, drive, or performance
  • loss or thinning of the hair
  • redness or discoloration of the skin
  • severe sunburn
  • swelling of the breasts or breast soreness in both females and males
  • swelling or inflammation of the mouth

For healthcare professionals

Applies to aspirin / omeprazole: oral delayed release tablet.

General adverse events

The most frequently reported side effects were gastritis, nausea, diarrhea, gastric polyps, and non-cardiac chest pain.[Ref]

Gastrointestinal

Aspirin:

Omeprazole:

Cardiovascular

Aspirin:

Omeprazole:

Dermatologic

Aspirin:

Omeprazole:

Hematologic

Aspirin:

Omeprazole:

Other

Aspirin:

Omeprazole:

Genitourinary

Aspirin:

Omeprazole:

Hepatic

Aspirin:

Omeprazole:

Metabolic

Aspirin:

Omeprazole:

Musculoskeletal

Aspirin:

Omeprazole:

Nervous system

Aspirin:

Omeprazole:

Endocrine

Omeprazole:

Oncologic

Omeprazole:

Psychiatric

Aspirin:

Omeprazole:

Renal

Aspirin:

Omeprazole:

Respiratory

Aspirin:

Omeprazole:

Ocular

Omeprazole:

Immunologic

Aspirin:

Omeprazole:

References

1. (2016) "Product Information. Yosprala (aspirin-omeprazole)." Aralez Pharmaceuticals

Further information

Yosprala side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.