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Xibrom Side Effects

Generic Name: bromfenac ophthalmic

Note: This page contains side effects data for the generic drug bromfenac ophthalmic. It is possible that some of the dosage forms included below may not apply to the brand name Xibrom.

For the Consumer

Applies to bromfenac ophthalmic: ophthalmic solution

As well as its needed effects, bromfenac ophthalmic (the active ingredient contained in Xibrom) may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking bromfenac ophthalmic, check with your doctor immediately:

More common:
  • Blurred vision
  • change in color vision
  • decreased vision or other changes in vision
  • difficulty seeing at night
  • eye pain
  • red, sore eyes
  • sensitivity to light
  • tearing

Minor Side Effects

Some bromfenac ophthalmic side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Abnormal sensation in the eye
  • burning or stinging of the eye
  • feeling of having something in the eye
  • headache
  • itching of the eyes

For Healthcare Professionals

Applies to bromfenac ophthalmic: ophthalmic solution


Common (1% to 10%): Anterior chamber inflammation, foreign body sensation in eye, vitreous floaters, iritis, eye pain, ocular hypertension, photophobia, blurred vision
Uncommon (0.1% to 1%): Reduced visual acuity, hemorrhagic retinopathy, corneal epithelium defect, corneal erosion, corneal epithelium disorder, corneal edema, retinal exudates, eyelid bleeding, eyelid edema, eye discharge, eye pruritus, eye irritation, eye redness, conjunctival hyperemia, ocular discomfort
Rare (less than 0.1%): Corneal perforation, corneal ulcer, corneal erosion, scleromalacia, corneal infiltrates, corneal disorder, corneal scar[Ref]


The most frequently reported side effects were foreign body sensation in eye, anterior chamber inflammation, headache, vitreous floaters, iritis, eye pain, photophobia, blurred vision, and ocular hypertension.[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]


Uncommon (0.1% to 1%): Face swelling[Ref]


Uncommon (0.1% to 1%): Epistaxis, cough, nasal sinus drainage
Rare (less than 0.1%): Asthma[Ref]


1. "Product Information. BromSite (bromfenac ophthalmic)." Sun Pharmaceutical Industries, Cranbury, NJ.

2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

3. "Product Information. Prolensa (bromfenac ophthalmic)." Bausch and Lomb, Rochester, NY.

4. "Product Information. Xibrom (bromfenac ophthalmic)." ISTA Pharmaceuticals, Irvine, CA.

It is possible that some side effects of Xibrom may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.