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Flurbiprofen ophthalmic

Generic name: flurbiprofen ophthalmic [ FLUR-bi-PROE-fen ]
Brand name: Ocufen
Dosage form: ophthalmic solution (0.03%)
Drug class: Ophthalmic anti-inflammatory agents

Medically reviewed by on Jun 30, 2021. Written by Cerner Multum.

What is flurbiprofen ophthalmic?

Flurbiprofen is a nonsteroidal anti-inflammatory drugs (NSAID).

Flurbiprofen ophthalmic (for the eye) is used to keep your pupils from constricting, or narrowing, during eye surgery.

Flurbiprofen ophthalmic may also be used for purposes not listed in this medication guide.


Use only as directed. Tell your doctor if you use other medicines or have other medical conditions or allergies.

Before taking this medicine

You should not use this flurbiprofen if you are allergic to it.

Tell your doctor if you have ever had:

It is not known if flurbiprofen will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

Ask a doctor if it is safe to breastfeed while using flurbiprofen ophthalmic.

Not approved for use by anyone younger than 18 years old.

How should I use flurbiprofen ophthalmic?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Flurbiprofen ophthalmic is usually given every 30 minutes beginning 2 hours before your surgery.

Wash your hands before using eye medication.

To apply the eye drops: Pull down your lower eyelid to create a small pocket and squeeze a drop into this pocket. Close your eyes for 1 or 2 minutes.

Use only the prescribed number of drops. Use in both eyes only if your doctor has told you to.

Do not touch the dropper tip or place it directly on your eye. A contaminated dropper can infect your eye and lead to serious vision problems.

If using this medicine in both eyes: You may be given 2 bottles of flurbiprofen ophthalmic. Assign a separate bottle to each eye, and use only that bottle in that eye (left or right).

Store at room temperature away from moisture and heat. Keep the bottle(s) tightly closed when not in use.

What happens if I miss a dose?

Call your doctor for instructions if you miss the dose given before your surgery. The 2-hour timing is very important for flurbiprofen ophthalmic to be effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222 if anyone has accidentally swallowed the medicine.

What should I avoid after I receive flurbiprofen ophthalmic?

Do not wear any contact lens that has not been approved by your doctor.

Do not use other eye medications unless your doctor tells you to.

Flurbiprofen ophthalmic side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Flurbiprofen ophthalmic may cause serious side effects. Call your doctor at once if you have:

  • eye pain or redness;

  • an appearance of blood inside your eye;

  • vision changes (your eyes may be more sensitive to light); or

  • severe burning, stinging, or itching of your eyes.

Common side effects of flurbiprofen ophthalmic may include:

  • mild burning or stinging; or

  • blurred or hazy vision.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Flurbiprofen ophthalmic dosing information

Usual Adult Dose for Inhibition of Intraoperative Miosis:

A total of 4 drops administered by instilling 1 drop approximately every half hour beginning 2 hours before surgery

Use: Inhibition of intraoperative miosis

What other drugs will affect flurbiprofen ophthalmic?

Tell your doctor about all your other medicines, especially:

Other drugs may affect flurbiprofen, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.