Vibativ Side Effects
Generic name: telavancin
Medically reviewed by Drugs.com. Last updated on Jun 18, 2022.
Note: This document contains side effect information about telavancin. Some dosage forms listed on this page may not apply to the brand name Vibativ.
Common side effects of Vibativ include: increased serum creatinine. Other side effects include: pruritus and skin rash. Continue reading for a comprehensive list of adverse effects.
Applies to telavancin: intravenous powder for solution.
Intravenous route (Powder for Solution)
Patients with preexisting moderate/severe renal impairment (CrCl 50 mL/min or less) who were treated with telavancin for hospital-acquired bacterial pneumonia/ventilator-associated bacterial pneumonia had increased mortality observed versus vancomycin. Use of telavancin in patients with pre-existing moderate/severe renal impairment (CrCl 50 mL/min or less) should be considered only when the anticipated benefit to the patient outweighs the potential risk. Nephrotoxicity: New onset or worsening renal impairment has occurred. Monitor renal function in all patients. Embryofetal toxicity: Telavancin may cause fetal harm. In animal reproduction studies, adverse developmental outcomes were observed in 3 animal species at clinically relevant doses. Verify pregnancy status prior to initiating treatment and advise females of reproductive potential to use effective contraception.
Serious side effects of Vibativ
Along with its needed effects, telavancin (the active ingredient contained in Vibativ) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking telavancin:
- Blood in the urine
- change in the frequency of urination or amount of urine
- difficulty with breathing
- increased thirst
- loss of appetite
- nausea or vomiting
- swelling of the feet or lower legs
Incidence not known
- Abdominal or stomach tenderness
- chills or fever
- difficulty with swallowing
- dizziness, faintness, or lightheadedness, especially when getting up suddenly from a lying or sitting position
- fast heartbeat
- hives or itching of the skin
- nausea or vomiting
- pain, redness, or soreness at the injection site
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- rash or redness of the face, base of the neck, upper body, back, and arms
- severe abdominal or stomach cramps and pain
- tightness in the chest
- unusual tiredness or weakness
- watery and severe diarrhea, which may also be bloody
Other side effects of Vibativ
Some side effects of telavancin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Bad, unusual or unpleasant (after) taste
- change in taste
- foamy urine
- Decreased appetite
- dry, red, hot, or irritated skin
- feeling unusually cold
For Healthcare Professionals
Applies to telavancin: intravenous powder for injection.
Very common (10% or more): All-cause mortality (up to 44%)
Common (1% to 10%): Fungal infection, fatigue, chills
Rare (less than 0.1%): Deafness[Ref]
Very common (10% or more): Increased serum creatinine to 1.5 times baseline (up to 16%), renal impairment/renal insufficiency/renal failure (up to 10%)
Common (1% to 10%): Acute renal failure, increased blood creatinine
Uncommon (0.1% to 1%): Increased blood urea[Ref]
Uncommon (0.1% to 1%): Anemia, leukopenia, thrombocythemia, thrombocytopenia, increased eosinophil count, increased neutrophil count, increased INR
Common (1% to 10%): QTc prolongation
Uncommon (0.1% to 1%): Angina pectoris, atrial fibrillation, bradycardia, congestive cardiac failure, prolonged electrocardiogram QT corrected interval, palpitations, sinus tachycardia, supraventricular extrasystoles, ventricular extrasystoles, flushing, hypertension, hypotension, phlebitis[Ref]
Very common (10% or more): Nausea (up to 27%), vomiting (up to 14%)
Common (1% to 10%): Diarrhea, constipation
Uncommon (0.1% to 1%): Hypersensitivity reactions
Very common (10% or more): Metallic/soapy taste disturbance (up to 33%), dysgeusia (more than 10%)
Common (1% to 10%): Headache, dizziness
Very common (10% or more): Foamy urine (up to 13%)
Common (1% to 10%): Increased ALT, increased AST
Uncommon (0.1% to 1%): Hepatitis
Common (1% to 10%): Pruritus, rash
Common (1% to 10%): Decreased appetite
Common (1% to 10%): Rigors
Uncommon (0.1% to 1%): Arthralgia, back pain, muscle cramp, myalgia
Uncommon (0.1% to 1%): Eye irritation, blurred vision
Common (1% to 10%): Insomnia
More about Vibativ (telavancin)
- Check interactions
- Pricing & coupons
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: glycopeptide antibiotics
- En español
Related treatment guides
1. "Product Information. Vibativ (telavancin)." Theravance Inc (2009):
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.