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Vectical Side Effects

Generic name: calcitriol topical

Medically reviewed by Last updated on Sep 15, 2022.

Note: This document contains side effect information about calcitriol topical. Some dosage forms listed on this page may not apply to the brand name Vectical.


Common side effects of Vectical include: hypercalcemia. Continue reading for a comprehensive list of adverse effects.

Applies to calcitriol topical: topical application ointment.

Serious side effects of Vectical

Along with its needed effects, calcitriol topical (the active ingredient contained in Vectical) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking calcitriol topical:

Incidence not known

  • Blistering, crusting, irritation, itching, or reddening, or burning feeling of the skin
  • confusion
  • cracked, dry, scaly skin
  • depression
  • dry mouth
  • headache
  • incoherent speech
  • increased urination
  • loss of appetite
  • metallic taste
  • muscle weakness
  • nausea
  • stomach pain
  • swelling
  • unusual tiredness
  • vomiting,
  • weight loss

Other side effects of Vectical

Some side effects of calcitriol topical may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

  • Skin itching or discomfort

For Healthcare Professionals

Applies to calcitriol topical: topical ointment.


Very common (10% or more): Hypercalcemia (16% to 24%)[Ref]


Common (1% to 10%): Laboratory test abnormality[Ref]


Common (1% to 10%): Skin discomfort, pruritus, skin irritation, erythema, psoriasis

Uncommon (0.1% to 1%): Dry skin

Frequency not reported: Skin edema, contact dermatitis

Postmarketing reports: Acute blistering dermatitis, erythema, skin burning sensation[Ref]


Common (1% to 10%): Urine abnormality, hypercalciuria[Ref]


Uncommon (0.1% to 1%): Kidney stones[Ref]


The most commonly reported side effect was hypercalcemia.[Ref]


1. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

2. "Product Information. Vectical (calcitriol topical)." Galderma Laboratories Inc (2009):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.