Skip to Content

Urispas Side Effects

Generic Name: flavoxate

Note: This document contains side effect information about flavoxate. Some of the dosage forms listed on this page may not apply to the brand name Urispas.

For the Consumer

Applies to flavoxate: oral tablet

Along with its needed effects, flavoxate (the active ingredient contained in Urispas) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur while taking flavoxate:

Rare Symptoms of overdose
  • Clumsiness or unsteadiness
  • dizziness (severe)
  • drowsiness (severe)
  • fever
  • flushing or redness of face
  • hallucinations (seeing, hearing, or feeling things that are not there)
  • shortness of breath or troubled breathing
  • unusual excitement, nervousness, restlessness, or irritability

Some side effects of flavoxate may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Drowsiness
  • dryness of mouth and throat
Less common or rare

For Healthcare Professionals

Applies to flavoxate: oral tablet


Flavoxate (the active ingredient contained in Urispas) is generally well tolerated and an estimated frequency of particular side effects is not available.[Ref]


Cardiovascular side effects have included tachycardia and palpitation.[Ref]


Gastrointestinal side effects have included nausea, vomiting, and dry mouth.[Ref]


Ocular side effects have included increased ocular tension, blurred vision, and altered accommodation.[Ref]

Nervous system

Nervous system side effects have included vertigo, headache, mental confusion, drowsiness, and nervousness. These effects may be exaggerated in elderly patients.[Ref]


Renal side effects have included dysuria, and obstructive uropathies of the lower urinary tract.[Ref]


Hypersensitivity side effects have included urticaria and other unspecified dermatoses, eosinophilia, and elevated temperature.[Ref]


Hematologic side effects have been reported rarely. A case of reversible leukopenia has been reported.[Ref]


1. "Product Information. Uripas (flavoxate)." SmithKline Beecham, Philadelphia, PA.

2. Baert L "Controlled double-blind trail of flavoxate in painful conditions of the lower urinary tract." Curr Med Res Opin 2 (1974): 631-5

3. Delaere KP, Michiels HG, Debruyne FM, Moonen WA "Flavoxate hydrochloride in the treatment of detrusor instability." Urol Int 32 (1977): 377-81

4. Pedersen E "Studies on the effect and mode of action of flavoxate in human urinary bladder and sphincter." Urol Int 32 (1977): 202-8

5. Jarvis GJ "A controlled trial of bladder drill and drug therapy in the management of detrusor instability." Br J Urol 53 (1981): 565-6

6. Bradley DV, Cazort RJ "Relief of bladder spasm by flavoxate. A comparative study." J Clin Pharmacol J New Drugs 10 (1970): 65-8

7. Milani R, Scalambrino S, Carrera S, Pezzoli P, Ruffmann R "Flavoxate hydrochloride for urinary urgency after pelvic radiotherapy: comparison of 600 mg versus 1200 mg daily dosages." J Int Med Res 16 (1988): 71-4

8. Hebjorn S "Treatment of detrusor hyperreflexia in multiple sclerosis: a double- blind, crossover clinical trial comparing methantheline bromid (Banthine), flavoxate chloride (Urispas) and meladrazine tartrat (Lisidonil)." Urol Int 32 (1977): 209-17

Some side effects of Urispas may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.