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Uniretic Side Effects

Generic Name: hydrochlorothiazide / moexipril

Note: This document contains side effect information about hydrochlorothiazide / moexipril. Some of the dosage forms listed on this page may not apply to the brand name Uniretic.

For the Consumer

Applies to hydrochlorothiazide / moexipril: oral tablet

Along with its needed effects, hydrochlorothiazide/moexipril may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking hydrochlorothiazide / moexipril:

Less common
  • Blurred vision
  • confusion
  • decreased urination
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • dry mouth
  • fast, slow, or irregular heartbeat
  • muscle cramps or pain
  • numbness, tingling, pain, or weakness in the hands or feet
  • rapid breathing
  • seizures
  • sunken eyes
  • sweating
  • thirst
  • trembling
  • unusual tiredness or weakness
  • weakness and heaviness of the legs
  • wrinkled skin

Some side effects of hydrochlorothiazide / moexipril may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Dry cough

For Healthcare Professionals

Applies to hydrochlorothiazide / moexipril: oral tablet


The most common adverse reactions were cough, dizziness, and fatigue.[Ref]


Common (1% to 10%): Fatigue, pain, flu syndrome, chest pain, peripheral edema, fever

Frequency not reported: Weakness[Ref]


Common (1% to 10%): Cough, upper respiratory infection, rhinitis, sinusitis, bronchitis

Frequency not reported: Respiratory distress, pneumonitis, pulmonary edema[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache, vertigo, hypertonia

Frequency not reported: Vertigo, dizziness, headache, paresthesia[Ref]


Common (1% to 10%): Diarrhea, abdominal pain, dyspepsia, nausea

Frequency not reported: Pancreatitis, sialadenitis, vomiting, diarrhea, cramping, nausea, gastric irritation, constipation[Ref]


Common (1% to 10%): Hyperuricemia, hyperglycemia, hypokalemia

Frequency not reported: Anorexia, hyperglycemia, hyperuricemia[Ref]


Common (1% to 10%): Urinary tract infection, impotence, pyuria

Frequency not reported: Glycosuria[Ref]


Common (1% to 10%): Rash

Frequency not reported: Stevens-Johnson syndrome, purpura, urticaria, rash, photosensitivity[Ref]


Common (1% to 10%): Abnormal ECG

Frequency not reported: Orthostatic hypotension, necrotizing angiitis[Ref]


Common (1% to 10%): Serum glutamic pyruvic transaminase (SGPT) increased

Frequency not reported: Intrahepatic cholestatic jaundice[Ref]


Common (1% to 10%): Back pain

Frequency not reported: Muscle spasm[Ref]


Common (1% to 10%): Infection[Ref]


Frequency not reported: Aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia[Ref]


Frequency not reported: Transient blurred vision, xanthopsia[Ref]


Frequency not reported: BUN increased, serum creatinine increased[Ref]


Frequency not reported: Restlessness[Ref]


1. "Product Information. Uniretic (hydrochlorothiazide-moexipril)." Schwarz Pharma, Mequon, WI.

Some side effects of Uniretic may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.