Trimethobenzamide Side Effects

Medically reviewed by Drugs.com. Last updated on Jan 10, 2025.

Applies to trimethobenzamide: intramuscular solution.

Other dosage forms:

• oral capsule

Common side effects of trimethobenzamide

Some side effects of trimethobenzamide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

• drowsiness

Less common side effects

• blurred vision
• diarrhea
• dizziness
• headache
• muscle cramps

Serious side effects of trimethobenzamide

Along with its needed effects, trimethobenzamide may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking trimethobenzamide:

Rare side effects

• body spasm, with head and heels bent backward and body bowed forward
• convulsions (seizures)
• depression
• shakiness or tremors
• skin rash
• sore throat or fever
• unusual tiredness
• vomiting (severe or continuing)
• yellow eyes or skin

For healthcare professionals

Applies to trimethobenzamide: compounding powder, intramuscular solution, oral capsule, rectal suppository.

Nervous system adverse events

• Frequency not reported: Coma, convulsions, disorientation, dizziness, drowsiness, headache, opisthotonos, Parkinson-like/extrapyramidal symptoms^[Ref]

Hypersensitivity

• Frequency not reported: Allergic-type skin reactions, angioedema, hypersensitivity reactions^[Ref]

Cardiovascular

• Frequency not reported: Hypotension^[Ref]

Psychiatric

• Frequency not reported: Depression^[Ref]

Gastrointestinal

• Frequency not reported: Diarrhea^[Ref]

Hepatic

• Frequency not reported: Jaundice^[Ref]

Musculoskeletal

• Frequency not reported: Muscle cramps^[Ref]

Hematologic

• Frequency not reported: Blood dyscrasias^[Ref]

Ocular

• Frequency not reported: Blurred vision^[Ref]

Further information

Trimethobenzamide side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer