Torsemide Side Effects

In Summary

Commonly reported side effects of torsemide include: polyuria. See below for a comprehensive list of adverse effects.

For the Consumer

Applies to torsemide: oral tablet

As well as its needed effects, torsemide may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking torsemide, check with your doctor immediately:

• Chest pain
• convulsions
• decreased urination
• diarrhea
• dry mouth
• increased thirst
• irregular heartbeat
• loss of appetite
• mood changes
• muscle pain or cramps
• nausea or vomiting
• numbness or tingling in the hands, feet, or lips
• shortness of breath
• swelling of the hands, ankles, feet, or lower legs
• unusual tiredness or weakness

• Black, tarry stools
• dizziness, faintness, or lightheadedness when getting up from a suddenly sitting or lying position
• ringing or buzzing in the ears or any hearing loss
• skin rash

If any of the following symptoms of overdose occur while taking torsemide, get emergency help immediately:

• Blurred vision
• coma
• confusion
• decreased urine output
• dizziness
• drowsiness
• fainting
• fast heartbeat
• headache
• increase in heart rate
• irritability
• lightheadedness
• rapid breathing
• sunken eyes
• sweating
• unusual tiredness or weakness
• weak pulse
• wrinkled skin

Minor Side Effects

Some torsemide side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

• Increase in urination

• Acid or sour stomach
• belching
• difficulty having a bowel movement (stool)
• difficulty in moving
• heartburn
• increased cough
• indigestion
• joint pain
• lack or loss of strength
• muscle pain or stiffness
• nervousness
• pain in the joints
• runny nose
• sneezing
• sore throat
• stomach discomfort, upset, or pain
• stuffy nose
• swollen joints
• trouble sleeping

For Healthcare Professionals

Applies to torsemide: injectable solution, oral tablet

General

The most common adverse reactions were headache and excessive urination.^[Ref]

Metabolic

Common (1% to 10%): Edema
Frequency not reported: Hyperglycemia, hyperuricemia, hypokalemia, hypovolemia, excessive thirst, gout, calcium excretion increased, serum calcium increased, serum calcium decreased, magnesium excretion increased, serum magnesium increased, serum magnesium decreased, BUN increased, creatinine increased, uric acid increased, serum glucose increased, total plasma cholesterol increased, plasma triglycerides increased^[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, constipation, nausea, dyspepsia, sore throat
Frequency not reported: Vomiting, esophageal hemorrhage, gastrointestinal hemorrhage, rectal bleeding, dry mouth
Postmarketing reports: Pancreatitis^[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness
Frequency not reported: Syncope, tinnitus, hearing loss, limb paresthesia^[Ref]

Other

Common (1% to 10%): Asthenia, chest pain
Frequency not reported: Weakness, digitalis intoxication^[Ref]

Musculoskeletal

Common (1% to 10%): Arthralgia, myalgia
Frequency not reported: Arthritis^[Ref]

Psychiatric

Common (1% to 10%): Insomnia, nervousness^[Ref]

Respiratory

Common (1% to 10%): Rhinitis, cough increased^[Ref]

Cardiovascular

Common (1% to 10%): ECG abnormality
Frequency not reported: Atrial fibrillation, hypotension, shunt thrombosis, ventricular tachycardia^[Ref]

Genitourinary

Common (1% to 10%): Excessive urination
Frequency not reported: Impotence^[Ref]

Hematologic

Frequency not reported: Red blood cells decreased, white blood cells decreased, platelets decreased, hemoglobin decreased, hematocrit decreased, erythrocyte count decreased, white blood cell count increased, platelet count increased, serum alkaline phosphatase increased
Postmarketing reports: Leukopenia, thrombocytopenia^[Ref]

Dermatologic

Frequency not reported: Rash, angioedema
Postmarketing reports: Stevens-Johnson syndrome, toxic epidermal necrolysis^[Ref]

Ocular

Frequency not reported: Visual disturbance^[Ref]

It is possible that some side effects of torsemide may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

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