Topco Allergy Side Effects

Generic name: chlorpheniramine

Medically reviewed by Drugs.com. Last updated on Jan 26, 2024.

Note: This document provides detailed information about Topco Allergy Side Effects associated with chlorpheniramine. Some dosage forms listed on this page may not apply specifically to the brand name Topco Allergy.

Applies to chlorpheniramine: oral syrup, oral tablet, oral tablet extended release.

Important warnings This medicine can cause some serious health issues

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

You should not use this medicine if you have narrow-angle glaucoma, a blockage in your stomach or intestines, an enlarged prostate, if you are unable to urinate, or if you are having an asthma attack.

Get emergency medical help if you have any of these signs of an allergic reaction while taking chlorpheniramine (the active ingredient contained in Topco Allergy) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using chlorpheniramine and call your doctor at once if you have:

• fast or uneven heart rate;

• mood changes;

• tremor, seizure (convulsions);

• easy bruising or bleeding, unusual weakness;

• feeling short of breath; or

• little or no urinating.

Common side effects may include:

• dizziness, drowsiness;

• dry mouth, nose, or throat;

• constipation;

• blurred vision; or

• feeling nervous or restless.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to chlorpheniramine: compounding powder, injectable solution, oral capsule extended release, oral liquid, oral suspension extended release, oral syrup, oral tablet, oral tablet chewable, oral tablet extended release.

Nervous system adverse events

• Very common (10% or more): Sedation, somnolence
• Common (1% to 10%): Disturbance in attention, abnormal coordination, dizziness, headache^[Ref]

Nearly all patients treated with chlorpheniramine experience drowsiness. This drowsiness may subside in some patients with extended use.

Few cases of dyskinesias and tremors, often of the face, have been reported in patients whose chronic use of chlorpheniramine extended over a period of 3 to 10 years. Some of these cases were only partially relieved by discontinuation of the drug. Haloperidol was successful in relieving symptoms.^[Ref]

Cardiovascular

• Frequency not reported: Palpitations, tachycardia, arrhythmias, hypotension^[Ref]

Ocular

• Common (1% to 10%): Blurred vision^[Ref]

Gastrointestinal

• Common (1% to 10%): Nausea, dry mouth
• Frequency not reported: Vomiting, abdominal pain, diarrhea, dyspepsia^[Ref]

Hypersensitivity

• Frequency not reported: Allergic reaction, angioedema, anaphylactic reactions^[Ref]

Dermatologic

• Frequency not reported: Exfoliative dermatitis, rash, urticaria, photosensitivity^[Ref]

Other

• Common (1% to 10%): Fatigue
• Frequency not reported: Tinnitus, chest tightness^[Ref]

Psychiatric

• Frequency not reported: Confusion, excitation, irritability, nightmares, depression^[Ref]

Hematologic

• Frequency not reported: Hemolytic anemia, blood dyscrasias^[Ref]

A fatal case of agranulocytosis has been reported in a patient taking chlorpheniramine, pseudoephedrine, acetaminophen, dextromethorphan, phenylpropanolamine, and aspirin. Chlorpheniramine was felt to be the cause.^[Ref]

Genitourinary

• Frequency not reported: Urinary retention^[Ref]

Musculoskeletal

• Frequency not reported: Muscle twitching, muscle weakness^[Ref]

Hepatic

• Frequency not reported: Hepatitis, jaundice^[Ref]

Respiratory

• Frequency not reported: Thickening of bronchial secretions^[Ref]

Metabolic

• Frequency not reported: Anorexia^[Ref]

Frequently asked questions

• Can you take antihistamines when pregnant?

Further information

Topco Allergy side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer