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Tolectin 600 Side Effects

Generic name: tolmetin

Medically reviewed by Drugs.com. Last updated on May 6, 2023.

Note: This document contains side effect information about tolmetin. Some dosage forms listed on this page may not apply to the brand name Tolectin 600.

Applies to tolmetin: oral capsule, oral tablet.

Warning

Oral route (Tablet; Capsule)

NSAIDs may cause an increased risk of serious cardiovascular thrombotic events, myocardial infarction, and stroke, which can be fatal. This risk may be increased with duration of use and in patients with cardiovascular disease or risk factors for cardiovascular disease. Tolmetin is contraindicated for the treatment of perioperative pain in the setting of CABG surgery. NSAIDs can also cause an increased risk of serious, sometimes fatal, gastrointestinal adverse events (eg, bleeding, ulceration, and perforation of the stomach or intestines), especially in the elderly. These events can occur at any time during use and without warning.

Serious side effects of Tolectin 600

Along with its needed effects, tolmetin (the active ingredient contained in Tolectin 600) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking tolmetin:

More common

Less common

Rare

Other side effects of Tolectin 600

Some side effects of tolmetin may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

Rare

For Healthcare Professionals

Applies to tolmetin: oral capsule, oral tablet.

Gastrointestinal

Very common (10% or more): Nausea (11%)

Common (1% to 10%): Dyspepsia, gastrointestinal (GI) distress, abdominal pain, diarrhea, flatulence, vomiting, constipation, gastritis, peptic ulcer

Frequency not reported: GI bleeding, GI perforation, glossitis, stomatitis[Ref]

Hepatic

Frequency not reported: Hepatitis, liver function abnormalities[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness, drowsiness[Ref]

Hematologic

Common (1% to 10%): Hemoglobin decreased, hematocrit decreased

Frequency not reported: Lymphadenopathy, hemolytic anemia, thrombocytopenia, granulocytopenia, agranulocytosis[Ref]

Renal

Common (1% to 10%): BUN increased

Frequency not reported: Renal failure[Ref]

Hypersensitivity

Frequency not reported: Anaphylactoid reactions[Ref]

Dermatologic

Common (1% to 10%): Skin irritation

Frequency not reported: Urticaria, purpura, erythema multiforme, toxic epidermal necrolysis[Ref]

Cardiovascular

Common (1% to 10%): Blood pressure increased

Frequency not reported: Congestive heart failure[Ref]

General

The most frequently reported side effect was nausea.[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection

Frequency not reported: Hematuria, proteinuria, dysuria[Ref]

Immunologic

Frequency not reported: Serum sickness

Ocular

Common (1% to 10%): Visual disturbance

Frequency not reported: Optic neuropathy, retinal/macular changes[Ref]

Other

Common (1% to 10%): Asthenia, chest pain, edema, weight gain, weight loss, tinnitus

Frequency not reported: Fever[Ref]

Psychiatric

Common (1% to 10%): Depression[Ref]

Respiratory

Frequency not reported: Epistaxis[Ref]

References

1. Product Information. Tolectin (tolmetin). McNeil Pharmaceutical. 2001;PROD.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.