Tilade Side Effects
Generic name: nedocromil
Medically reviewed by Drugs.com. Last updated on May 6, 2022.
Note: This document contains side effect information about nedocromil. Some of the dosage forms listed on this page may not apply to the brand name Tilade.
Applies to nedocromil: inhalation aerosol with adapter
Gastrointestinal
Gastrointestinal side effects have included unpleasant taste which was reported in approximately 13% of patients receiving nedocromil (the active ingredient contained in Tilade) and resulted in drug withdrawal in up to 3%. Less commonly, nedocromil has caused nausea and vomiting (2% to 4%).[Ref]
Respiratory
Throat irritation may be relieved by drinking water before and after inhalation of nedocromil (the active ingredient contained in Tilade) Use of a beta-2 agonist prior to nedocromil inhalation may relieve cough and bronchospasm.[Ref]
Respiratory side effects have included cough and throat irritation in 6% to 7% of patients treated with nedocromil. Bronchospasm has been induced in 5% of patients.[Ref]
Nervous system
Nervous system side effects have included headache in up to 6% of patients treated. Less commonly dizziness has been reported.[Ref]
Hepatic
Hepatic side effects have included elevations of liver function tests (SGPT) in approximately 3% of patients treated with nedocromil (the active ingredient contained in Tilade) [Ref]
More about Tilade (nedocromil)
- Drug interactions
- Dosage information
- During pregnancy or Breastfeeding
- Drug class: mast cell stabilizers
Professional resources
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References
1. Dejong JW, Demonchy JGR, Teengs JP, Postma DS, Koeter GH, Vandermark TW "Nedocromil sodium versus albuterol in the management of allergic asthma." Am J Respir Crit Care Med 149 (1994): 91-7
2. Boulet LP, Cartier A, Keshmiri M, Kesten S, Laberge F, Lee-Chuy E, Rebuck AS, Cockcroft D, MacDonald GF, Gruber J, et al. "A 3-month evaluation of the efficacy of nedocromil sodium in asthma: a randomized, double-blind, placebo-controlled trial of nedocromil sodium conducted by a Canadian multicenter study group." J Allergy Clin Immunol 85 (1990): 612-7
3. Foulds RA "An overview of human safety data with nedocromil sodium." J Allergy Clin Immunol 92 (1993): 202-4
4. Parish RC, Miller LJ "Nedocromil sodium." Ann Pharmacother 27 (1993): 599-606
5. Brogden RN, Gonzalez JP "Nedocromil sodium. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy in the treatment of reversible obstructive airways disease." Drugs 34 (1987): 560-77
6. Brogden RN, Sorkin EM "Nedocromil sodium. An updated review of its pharmacological properties and therapeutic efficacy in asthma." Drugs 45 (1993): 693-715
7. "Product Information. Tilade (nedocromil)." Rhone Poulenc Rorer (2001):
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.