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Thyrolar-2 Side Effects

Generic name: liotrix

Medically reviewed by Last updated on Mar 17, 2022.

Note: This document contains side effect information about liotrix. Some dosage forms listed on this page may not apply to the brand name Thyrolar-2.

Applies to liotrix: oral tablets.

Side effects include:

Adverse reactions result from overdosage and resemble manifestations of hyperthyroidism, including fatigue, weight loss, increased appetite, heat intolerance, fever, excessive sweating, headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia, tremor, muscle weakness, palpitations, tachycardia, arrhythmias, increased heart rate and BP, heart failure, angina, AMI, cardiac arrest, diarrhea, vomiting, abdominal cramps, elevations in liver function test results, hair loss, flushing, decreased bone mineral density, menstrual irregularities, and impaired fertility.

For Healthcare Professionals

Applies to liotrix: oral tablet.


Adverse reactions other than those attributable to hyperthyroidism due to therapeutic overdose are rare. Excessive doses may result in a hypermetabolic state resembling in every respect the condition of endogenous origin.[Ref]


Postmarketing reports: Hypothyroidism, thyroid stimulating hormone (TSH) increased, TSH decreased[Ref]


Postmarketing reports: Palpitation, blood pressure increased, heart rate increased[Ref]


Postmarketing reports: Alopecia, dry skin, urticaria, hyperhidrosis, pruritus[Ref]


Postmarketing reports: Hypersensitivity[Ref]


Postmarketing reports: Arthralgia, myalgia[Ref]


Postmarketing reports: Keratoconjunctivitis sicca[Ref]


Postmarketing reports: Fatigue, sluggishness, weight increased, asthenia, chest pain[Ref]

Nervous system

Postmarketing reports: Headache, tremor[Ref]


Postmarketing reports: Nausea[Ref]


Postmarketing reports: Anxiety, depression, insomnia[Ref]

More about Thyrolar-2 (liotrix)

Patient resources

Other brands


Professional resources

Related treatment guides


1. "Product Information. Thyrolar (liotrix)." Forest Pharmaceuticals (2001):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.