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User Reviews for Liothyronine

Also known as: Cytomel, Triostat

Liothyronine has an average rating of 6.7 out of 10 from a total of 77 ratings on Drugs.com. 62% of those users who reviewed Liothyronine reported a positive effect, while 34% reported a negative effect.

Condition Avg. Rating Reviews Compare
Underactive Thyroid  
6.3
57 reviews 33 medications
Hypothyroidism, After Thyroid Removal  
8.0
20 reviews 27 medications
Summary of Liothyronine reviews 6.7 77 reviews

Reviews may be moderated or edited before publication to correct grammar and spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest in the medication will not be published. As reviews and ratings are subjective and self-reported, this information should not be used as the basis for any statistical analysis or scientific studies.

Reviews for Liothyronine

Solskind May 15, 2021

Cytomel (liothyronine) for Underactive Thyroid: “Started Cytomel 5 mg about 8 days ago. As my t-3 was low. And just did not feel well I had hair loss , weight gain , major constipated, and very irritable, dry skin. I am hoping to feel better and be more regulated in many ways. I curious what everyone’s t-3 number were before starting .?? Cytomel. may be too soon for me to notice any change yet ? Thank you”

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Vi · Taken for 10 years or more April 5, 2021

For Hypothyroidism, After Thyroid Removal: “I have been doing well on 5mcg once a of Cytomel for over ten years. Taking the brand name made by Pfizer, not the generic one.”

10 / 10
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ME · Taken for 1 to 6 months March 21, 2021

Cytomel (liothyronine) for Underactive Thyroid: “This medication is horrible! I have had severe adverse reactions on both the brand name and generic form. Painful limp knees, tachycardia, palpitations, and all of my hair fell out! Never again will I take this medication. It’s not worth my life.”

1 / 10
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HW2583 · Taken for less than 1 month March 2, 2021

Cytomel (liothyronine) for Underactive Thyroid: “1st day of taking this medication and I feel amazing. I have been on Synthroid (levothyroxine) for 15 years. I finally broke down and asked my Endocrinologist if I would ever have a life again. He decided to lower the Synthroid and add the Cytomel. My energy on the first day was astounding. Will update with any changes.”

10 / 10
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Mich February 23, 2014

Cytomel (liothyronine) for Underactive Thyroid: “I suffered for 5 years with Anxiety and Depression. I tried many, many antidepressants. Nothing worked. My T3 levels were very low but my TSH was only slightly high. One doctor treated me with Synthroid but I had no changes. I saw many doctors including an endocrinologist that told me that nothing was wrong with my thyroid. After spending many hours online looking for answers, I found an endocrinologist that said he would try treating me with Cytomel. Within a day I felt AMAZING! It was like someone put new batteries in my body! I am finally able to be happy and live life again! Truly a Miracle!”

10 / 10
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Ash RN October 3, 2013

Cytomel (liothyronine) for Underactive Thyroid: “I was on Synthroid only for 8 years after being diagnosed with Hypothyroidism . My dose was changed many times over that time frame by 4 different Endocrinologists but I still felt bad, weight gain, fogginess, depression, chronic fatigue you name it. 6 weeks ago I was put on 10 mcg of Cytomel by a new doc that I am seeing a 100 miles from my home town and I am happy to say for the first time in 8 years I have relief from my symptoms. I have lost 10 pounds in 6 weeks. I am happy not in a fog anymore and I have energy to enjoy life once again. The Cytomel made all the difference. ”

10 / 10
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Anonymous November 2, 2010

Cytomel (liothyronine) for Underactive Thyroid: “My doctor and I tried every T4 medication out there, and although I felt better I still wasn't right. After 2 years he switched me to Cytomel and I immediately knew I had found the solution. All the hypo symptoms disappeared - constipation, depression, weight gain and exhaustion. My cholesterol dropped to 140... in fact, all my blood work is excellent. It's very discouraging to know you're doing everything right - diet, exercise, sleep - and not only do your lab numbers not respond, but doctors tend to think you're not telling them the truth. Finally found a doctor that believed me; finally found the right medication. Life is good!”

9 / 10
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Kathy June 4, 2020

Cytomel (liothyronine) for Underactive Thyroid: “I took Armour Thyroid for a few years felt ok but still gaining weight and not much energy. Then I was switched to levothyroxine and felt about the same. Then added 2x 5 mcg of Cytomel. It literally knocked me out for hours after taking the first two days. Then when I woke up it was like somebody turned the lights on in the room. Everything seemed clearer and I could think straighter again. I love the stuff. I take 1 2x day 6 hours apart.”

10 / 10
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Cher · Taken for less than 1 month June 18, 2020

Cytomel (liothyronine) for Underactive Thyroid: “Synthroid is the problem most of you have, not the Cytomel. Medical school materials were furnished and influenced by Big Pharma to keep us sick and depending on their harmful drugs. If you develop joint and bone and swelling pain. Insist your dr. tries you on T3 only starting at 1/2 of 5mcg and increase to 5mcg and if needed continue in small dosages until you're feeling normal again. No need to be on T4. Doctor's don't need to go by your t4 blood levels, they need to go by your t3 and how you're feeling. Not everyone is the same in body weight, height, immune system, etc. Eventually if you want to heal from thyroids meds you need to see a Naturopath doctor that will treat your liver toxicity!”

10 / 10
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Tammy · Taken for 1 to 6 months March 20, 2018

Cytomel (liothyronine) for Underactive Thyroid: “I am so angry at every doctor that told me my TSH and T4 were normal and I was fine. After many years I switched doctors and the new doc was the first one that tested T3, mine was very low so I started taking cytomel and am feeling great! All those wasted years I could cry.”

10 / 10
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A Complicated Patient · Taken for less than 1 month March 15, 2015

Cytomel (liothyronine) for Underactive Thyroid: “Synthroid by itself was not effective. It is of great interest to me that so many other people have had the experience of being told by a physician that everything is fine while everything was, decidedly, NOT FINE! (making long story short due to length restriction. Details need space.) Large dosage of Synthroid ineffective, nurse practitioner certain nothing wrong, physician A dosage is ok but maybe a small bump, small effect for short period then return to prebump effect, concerned that observation due to psychological rather than physiological waited, physician B does further workup, physician B sees most of Syntroid dosage going to reverse T3 (physiologically ineffective) adds Cytomel, the improvement was immediate; not psych.”

10 / 10
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Jo · Taken for 6 months to 1 year April 26, 2019

Cytomel (liothyronine) for Underactive Thyroid: “I have been hashimoto thyroiditis and had my TSH get up to 55.2. I was being treated with synthroid and got up to 100mcg. I was not converting the T4 to T3, so I asked for cytomel. It took a bit to get the correct dosage, but this hormone gave me back my life.”

10 / 10
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Anonymous August 11, 2009

Cytomel (liothyronine) for Underactive Thyroid: “Adding 10mcg of Cytomel to my T4 medicine was just what my body needed to clear up those lingering hypothyroid symptoms that just wouldn't go away, no matter how good my lab numbers looked or other healthy habits I developed. Doctors seem really hesitant to prescribe it, but if you're hypothyroid and T4 alone isn't working, your body just might need some T3.”

9 / 10
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Anonymous · Taken for 10 years or more July 13, 2018

Cytomel (liothyronine) for Underactive Thyroid: “I took Synthroid for several years and kept telling doctors that I didn't feel good. I kept gaining weight, my joints hurt and I had no energy. More than one doctor told me I didn't have a problem, that it was all in my head and that nothing was wrong with me. After my second child, I have figured out that it was the medicine and weaned myself off of it. With a TSH of 72 I lost 60 pounds, my joint pain went away and my energy came back. A wonderful OBGYN found out about me and my TSH score when I got pregnant with my third child. He was smart enough to talk me into trying T3 Cytomel. It has been a God send. I have taken it faithfully for 20 years and would not miss a single dose. I can't live without it.”

10 / 10
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Mieke · Taken for 2 to 5 years July 10, 2019

Cytomel (liothyronine) for Hypothyroidism, After Thyroid Removal: “Changed my life. On Synthroid only felt exhausted and totally dysfunctional. Adding Cytomel improved my well-being, mood and energy level. It does have a greater reducing factor on your TSH. But so what. I do not have a thyroid, my bones and cardiac function are fine and I feel normal. Endocrinologists often feel that adding T3 is not necessary. They need to change their thinking.”

10 / 10
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Tiny · Taken for 1 to 6 months June 10, 2019

Cytomel (liothyronine) for Hypothyroidism, After Thyroid Removal: “An endocrinologist put me on the (50 mg) day post TT. I felt tremendous. Then my insurance changed and I had to find a new doctor. The new doctor refused to prescribe Cytomel. So for several years I’ve been on Synthroid 200 and 300 and then Nature Throid 3 grains. The Nature Thyroid won out over the Synthroid by far. But my total T3 and FT3 were still tanked. I began seeing a functional medicine doctor who suggested T3 only medication. WHAT A LIFE CHANGER! I take 25 mg/day. Gone is the anxiety, mood swings, depression, weight gain, brain fog and insomnia. I feel like a brand new person at 62. My doctor follows my labs closely and all thyroid levels are in range (FT3 upper range, FT4 mid range). I highly recommend trying this mono therapy if you don’t have a thyroid gland and other medication regimens have failed.”

10 / 10
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LittleDove32 May 28, 2017

Cytomel (liothyronine) for Underactive Thyroid: “Cytomel is making my brain work so much better again! I tried it several years ago and it made me me jittery, I felt like I had a huge amount of caffeine in me.... not this time! I'm in peri menopause and I understand the estrogen dominance can be a thyroid hormone antagonist, making it difficult to convert. Cytomel has helped me feel almost entirely back to normal and I have the energy to exercise again!”

10 / 10
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Bev7113 · Taken for 2 to 5 years November 11, 2016

Cytomel (liothyronine) for Underactive Thyroid: “I have had hypothyroidism for over twenty years now. Took high levels of Synthroid for years and felt ok but not perfect. Started Cytomel 3 years ago, regulated dosage until it was just right. It takes a little time to regulate it to your exact dosage but be patient, it's worth it.”

10 / 10
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Bigi · Taken for less than 1 month July 1, 2012

Cytomel (liothyronine) for Hypothyroidism, After Thyroid Removal: “I had my thyroid removed 3 years ago. I have been on various T4 supplements since: Synthroid, levothyroxine, Tirosint and continued to complain of fatigue, fogginess, wt gain, achiness, shortness of breath at exercise. FINALLY switched doctors as my Indian doctor would not try Armour. The new nurse practitioner looked at my labs: high T4, nonexistent T3. She switched me back to Synthroid and decreased the dosage, then added, for the FIRST time, Cytomel (T3). Within 3 days I have noticed a HUGE difference. So happy and still know the time test. BUT, fog is lifting, energy level increasing, sleeping well, HAPPY. I am hoping this continues. Noticed a slight headache at first but not bad. Will continue to cautiously be excited that we are ON to something.”

9 / 10
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ayahuasca · Taken for 1 to 6 months September 26, 2016

Cytomel (liothyronine) for Underactive Thyroid: “Was treated with antidepressants and anti-psychotics for almost a year since the doctor's opinion was that my symptoms of weight gain, lack of energy, depression and dizziness were due to psychosis. Only after a year I was given a blood test and told that I have autoimmune disease. No longer take any antidepressants or anti-psychotics, only take 12.5 mcg in the morning. Can now sleep 8 instead of 14 hours a day, feel awake during the day, have energy and willingness to do things. Definitely helped with depression and anxiety. If only the blood test was performed earlier!”

10 / 10
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Courtneyg · Taken for 6 months to 1 year January 18, 2020

Cytomel (liothyronine) for Underactive Thyroid: “Hashimotos patient. Take 88mcg of synthroid and took 5 McG of cytomel for almost a year. Felt better at first and then felt completely insane. Mood swings, anxiety, depression, rage, tachycardia and hand tremors. Sketchy stuff that. If you feel crazy, cut the cytomel before you get on or up your antidepressants.”

3 / 10
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Laurie B August 31, 2019

Cytomel (liothyronine) for Hypothyroidism, After Thyroid Removal: “I have had Hashimoto's hypothyroidism for 40 years. I was on generic levothyroxine for most of that time. As I reached 50 my new endocrinologist decided I should add 5mcg (of very potent) T3 aka Cytomel to my 150mcg of levothyroxine. Initially like many patients I felt great, then it got real bad. I am sorry, I know some people do very well on it, BUT many do not. Here is what I experienced in order of severity- Super dark Thoughts Severe Depression Rage Rapidly Cycling Moods Facial Swelling Extreme Itching Nighttime Coughing Intense Migraines Insomnia Heat Intolerance Dilated Neck Veins Extreme Fatigue Hot Flashes with the Inability to Sweat If you experience any or all of these You Are Not Alone and You Are NOT Crazy!”

1 / 10
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Aussie Shepherd · Taken for 1 to 6 months January 12, 2020

Cytomel (liothyronine) for Underactive Thyroid: “Have been on synthroid and thyroid for years. Never felt completely well on either one of them. Thyroid levels have been up and down for the past 2 years and can never seem to have a good balance between t3 and t4. Endocrinologist reduced my synthroid and added Cytomel 2 times a day. Have been taking this almost 2 months and I am finally getting back some energy. My t3 and t4 levels are finally balancing out. I no longer have to take naps all day because I am tired. Muscle aches have subsided and feeling positive for the first time in a long time. I hope this continues.”

10 / 10
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Sunshine7580 September 29, 2010

Cytomel (liothyronine) for Hypothyroidism, After Thyroid Removal: “I've taken this medication for a month and I can say it has changed my life: more energy, more sex drive and losing weight. Only drawback was I get migraine headaches when I don't drink enough water. Drink lots of water with this medication.”

9 / 10
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Mell · Taken for 6 months to 1 year March 9, 2020

Cytomel (liothyronine) for Underactive Thyroid: “Have been using Cytomel since 6/2019. I take every day along with levothyroxine for 5 days a week! What a difference. Before I couldn't get out of bed in the mornings, could hardly function. Know my numbers look great and I feel like a different person.”

10 / 10
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RootsGal · Taken for less than 1 month December 4, 2016

For Underactive Thyroid: “First, I diagnosed myself after being exhausted, unable to lose ANY weight even when I breast fed my son for a year. My periods were heavy and debilitating and no amount of exercise or diet allowed me to lose weight. Synthroid alone was clearly not enough, so after 14 years I switched endocrinologists. She called me a "doctor shopper", the first appointment, and said being cold all the time and 2 hour naps a day were NOT related to my thyroid. She reluctantly prescribed 5mcg of generic Cytomel BID. After only 4 days, the naps are a thing of the past! I cannot wait to see her face when she hears it worked! WHY are these doctors locked into ONLY care about "the numbers"?”

10 / 10
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Cypress February 26, 2021

Cytomel (liothyronine) for Underactive Thyroid: “I self diagnosed that my body wasn’t converting my synthroid into T3, and an endocrinologist agreed. I tried reducing Synthroid and adding desiccated T3 first, felt great, but I broke out with acne. Cytomel has worked in giving me much more energy, I can get by on 7/8 hours sleep instead of needing 10! I had arm pain at first, which went away with altering the dosage, then some unexplained abdominal pain, that disappeared. I am very happy with cytomels effects in giving me more energy! I used to need to take a cat nap at work to get through the day!”

9 / 10
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EMI January 24, 2020

For Underactive Thyroid: “Liothyronine saved my life. I was put on levothyroxine and was on it for 3 years in that time I became very ill and gained 3 stone and became housebound, I was drowning in my symptom depressed and suicidal. I came across t3 liothyronine in a support group. Started to take it raised it gradually and within 6 months I was back at work and recovering. I'm now back to normal, normal weight and a normal life”

10 / 10
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This information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare practitioners.