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User Reviews for Liothyronine to treat Underactive Thyroid

Also known as: Cytomel, Triostat

Liothyronine has an average rating of 6.3 out of 10 from a total of 66 ratings for the treatment of Underactive Thyroid. 58% of reviewers reported a positive experience, while 39% reported a negative experience.

Liothyronine rating summary

6.3/10 average rating

66 ratings from 69 user reviews.

Compare all 51 medications used in the treatment of Underactive Thyroid.

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Reviews for Liothyronine

Mich · February 23, 2014

Cytomel (liothyronine): “I suffered for 5 years with Anxiety and Depression. I tried many, many antidepressants. Nothing worked. My T3 levels were very low but my TSH was only slightly high. One doctor treated me with Synthroid but I had no changes. I saw many doctors including an endocrinologist that told me that nothing was wrong with my thyroid. After spending many hours online looking for answers, I found an endocrinologist that said he would try treating me with Cytomel. Within a day I felt AMAZING! It was like someone put new batteries in my body! I am finally able to be happy and live life again! Truly a Miracle!”

10 / 10
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Ash RN · October 3, 2013

Cytomel (liothyronine): “I was on Synthroid only for 8 years after being diagnosed with Hypothyroidism . My dose was changed many times over that time frame by 4 different Endocrinologists but I still felt bad, weight gain, fogginess, depression, chronic fatigue you name it. 6 weeks ago I was put on 10 mcg of Cytomel by a new doc that I am seeing a 100 miles from my home town and I am happy to say for the first time in 8 years I have relief from my symptoms. I have lost 10 pounds in 6 weeks. I am happy not in a fog anymore and I have energy to enjoy life once again. The Cytomel made all the difference. ”

10 / 10
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HW2583 · Taken for less than 1 month · March 2, 2021

Cytomel (liothyronine): “1st day of taking this medication and I feel amazing. I have been on Synthroid (levothyroxine) for 15 years. I finally broke down and asked my Endocrinologist if I would ever have a life again. He decided to lower the Synthroid and add the Cytomel. My energy on the first day was astounding. Will update with any changes.”

10 / 10
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Anonymous · November 2, 2010

Cytomel (liothyronine): “My doctor and I tried every T4 medication out there, and although I felt better I still wasn't right. After 2 years he switched me to Cytomel and I immediately knew I had found the solution. All the hypo symptoms disappeared - constipation, depression, weight gain and exhaustion. My cholesterol dropped to 140... in fact, all my blood work is excellent. It's very discouraging to know you're doing everything right - diet, exercise, sleep - and not only do your lab numbers not respond, but doctors tend to think you're not telling them the truth. Finally found a doctor that believed me; finally found the right medication. Life is good!”

9 / 10
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Tammy · Taken for 1 to 6 months · March 20, 2018

Cytomel (liothyronine): “I am so angry at every doctor that told me my TSH and T4 were normal and I was fine. After many years I switched doctors and the new doc was the first one that tested T3, mine was very low so I started taking cytomel and am feeling great! All those wasted years I could cry.”

10 / 10
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Cher · Taken for less than 1 month · June 18, 2020

Cytomel (liothyronine): “Synthroid is the problem most of you have, not the Cytomel. Medical school materials were furnished and influenced by Big Pharma to keep us sick and depending on their harmful drugs. If you develop joint and bone and swelling pain. Insist your dr. tries you on T3 only starting at 1/2 of 5mcg and increase to 5mcg and if needed continue in small dosages until you're feeling normal again. No need to be on T4. Doctor's don't need to go by your t4 blood levels, they need to go by your t3 and how you're feeling. Not everyone is the same in body weight, height, immune system, etc. Eventually if you want to heal from thyroids meds you need to see a Naturopath doctor that will treat your liver toxicity!”

10 / 10
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Kathy · June 4, 2020

Cytomel (liothyronine): “I took Armour Thyroid for a few years felt ok but still gaining weight and not much energy. Then I was switched to levothyroxine and felt about the same. Then added 2x 5 mcg of Cytomel. It literally knocked me out for hours after taking the first two days. Then when I woke up it was like somebody turned the lights on in the room. Everything seemed clearer and I could think straighter again. I love the stuff. I take 1 2x day 6 hours apart.”

10 / 10
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A Complicated Patient · Taken for less than 1 month · March 15, 2015

Cytomel (liothyronine): “Synthroid by itself was not effective. It is of great interest to me that so many other people have had the experience of being told by a physician that everything is fine while everything was, decidedly, NOT FINE! (making long story short due to length restriction. Details need space.) Large dosage of Synthroid ineffective, nurse practitioner certain nothing wrong, physician A dosage is ok but maybe a small bump, small effect for short period then return to prebump effect, concerned that observation due to psychological rather than physiological waited, physician B does further workup, physician B sees most of Syntroid dosage going to reverse T3 (physiologically ineffective) adds Cytomel, the improvement was immediate; not psych.”

10 / 10
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Anonymous · Taken for 10 years or more · July 13, 2018

Cytomel (liothyronine): “I took Synthroid for several years and kept telling doctors that I didn't feel good. I kept gaining weight, my joints hurt and I had no energy. More than one doctor told me I didn't have a problem, that it was all in my head and that nothing was wrong with me. After my second child, I have figured out that it was the medicine and weaned myself off of it. With a TSH of 72 I lost 60 pounds, my joint pain went away and my energy came back. A wonderful OBGYN found out about me and my TSH score when I got pregnant with my third child. He was smart enough to talk me into trying T3 Cytomel. It has been a God send. I have taken it faithfully for 20 years and would not miss a single dose. I can't live without it.”

10 / 10
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Anonymous · August 11, 2009

Cytomel (liothyronine): “Adding 10mcg of Cytomel to my T4 medicine was just what my body needed to clear up those lingering hypothyroid symptoms that just wouldn't go away, no matter how good my lab numbers looked or other healthy habits I developed. Doctors seem really hesitant to prescribe it, but if you're hypothyroid and T4 alone isn't working, your body just might need some T3.”

9 / 10
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LittleDove32 · May 28, 2017

Cytomel (liothyronine): “Cytomel is making my brain work so much better again! I tried it several years ago and it made me me jittery, I felt like I had a huge amount of caffeine in me.... not this time! I'm in peri menopause and I understand the estrogen dominance can be a thyroid hormone antagonist, making it difficult to convert. Cytomel has helped me feel almost entirely back to normal and I have the energy to exercise again!”

10 / 10
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Jo · Taken for 6 months to 1 year · April 26, 2019

Cytomel (liothyronine): “I have been hashimoto thyroiditis and had my TSH get up to 55.2. I was being treated with synthroid and got up to 100mcg. I was not converting the T4 to T3, so I asked for cytomel. It took a bit to get the correct dosage, but this hormone gave me back my life.”

10 / 10
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Bev7113 · Taken for 2 to 5 years · November 11, 2016

Cytomel (liothyronine): “I have had hypothyroidism for over twenty years now. Took high levels of Synthroid for years and felt ok but not perfect. Started Cytomel 3 years ago, regulated dosage until it was just right. It takes a little time to regulate it to your exact dosage but be patient, it's worth it.”

10 / 10
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ayahuasca · Taken for 1 to 6 months · September 26, 2016

Cytomel (liothyronine): “Was treated with antidepressants and anti-psychotics for almost a year since the doctor's opinion was that my symptoms of weight gain, lack of energy, depression and dizziness were due to psychosis. Only after a year I was given a blood test and told that I have autoimmune disease. No longer take any antidepressants or anti-psychotics, only take 12.5 mcg in the morning. Can now sleep 8 instead of 14 hours a day, feel awake during the day, have energy and willingness to do things. Definitely helped with depression and anxiety. If only the blood test was performed earlier!”

10 / 10
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Courtneyg · Taken for 6 months to 1 year · January 18, 2020

Cytomel (liothyronine): “Hashimotos patient. Take 88mcg of synthroid and took 5 McG of cytomel for almost a year. Felt better at first and then felt completely insane. Mood swings, anxiety, depression, rage, tachycardia and hand tremors. Sketchy stuff that. If you feel crazy, cut the cytomel before you get on or up your antidepressants.”

3 / 10
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Aussie Shepherd · Taken for 1 to 6 months · January 12, 2020

Cytomel (liothyronine): “Have been on synthroid and thyroid for years. Never felt completely well on either one of them. Thyroid levels have been up and down for the past 2 years and can never seem to have a good balance between t3 and t4. Endocrinologist reduced my synthroid and added Cytomel 2 times a day. Have been taking this almost 2 months and I am finally getting back some energy. My t3 and t4 levels are finally balancing out. I no longer have to take naps all day because I am tired. Muscle aches have subsided and feeling positive for the first time in a long time. I hope this continues.”

10 / 10
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RootsGal · Taken for less than 1 month · December 4, 2016

“First, I diagnosed myself after being exhausted, unable to lose ANY weight even when I breast fed my son for a year. My periods were heavy and debilitating and no amount of exercise or diet allowed me to lose weight. Synthroid alone was clearly not enough, so after 14 years I switched endocrinologists. She called me a "doctor shopper", the first appointment, and said being cold all the time and 2 hour naps a day were NOT related to my thyroid. She reluctantly prescribed 5mcg of generic Cytomel BID. After only 4 days, the naps are a thing of the past! I cannot wait to see her face when she hears it worked! WHY are these doctors locked into ONLY care about "the numbers"?”

10 / 10
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jillianmarie83 · February 25, 2015

Cytomel (liothyronine): “After being hypothyroid for many years and having good results on Synthroid and natural thyroid, it went on backorder for a few months and I had to switch to Cytomel. I felt immediate changes, more alert and a little more energy. However, after taking it for a few years, about 70% of my hair fell out (in clumps and I tried everything to stop the hair loss), and I've had chronic insomnia, huge appetite increase, higher blood pressure, anxiety attacks, hot flashes, etc. ”

2 / 10
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Mell · Taken for 6 months to 1 year · March 9, 2020

Cytomel (liothyronine): “Have been using Cytomel since 6/2019. I take every day along with levothyroxine for 5 days a week! What a difference. Before I couldn't get out of bed in the mornings, could hardly function. Know my numbers look great and I feel like a different person.”

10 / 10
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Janine Maria · June 10, 2016

“I have had Hashimoto''s thyroiditis since 2003. I've been on Armour; I've been on Naturthroid and I've been on Synthroid. it's been a struggle to keep the weight off or get any weight off. I diet and exercise very stringently. You won't believe this: 25 mcg Synthroid and 5 mcg twice a day Lyothyroninr (Cytomel, or T-3) and the weight is practically falling off. I started on it May 13, 2016. That's 4 weeks. It started a few days ago and is I'm losing over a pound a day, sometimes 2. I wish I had known. See, my body makes antibodies to the desiccated porcine thyroid, as well as to my own. That's supposedly very rare. They were three times as high on Armour and Naturthroid as my own thyroid, and it's pretty high anyway.”

10 / 10
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EMI · January 24, 2020

“Liothyronine saved my life. I was put on levothyroxine and was on it for 3 years in that time I became very ill and gained 3 stone and became housebound, I was drowning in my symptom depressed and suicidal. I came across t3 liothyronine in a support group. Started to take it raised it gradually and within 6 months I was back at work and recovering. I'm now back to normal, normal weight and a normal life”

10 / 10
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Alexa1285 · Taken for 6 months to 1 year · April 3, 2019

Cytomel (liothyronine): “My doctor recommended this since my symptoms weren't going away on levothyroxine alone. Worst year of my life. Mood swings and crippling anxiety. This drug made me completely irrational and the anxiety got so bad daily activities like driving my car would make my heart race and hands shake. Wish I could get that year of my life back.”

1 / 10
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R · Taken for less than 1 month · December 27, 2019

Cytomel (liothyronine): “Upon 5 days of taking Cytomel at a dose of 5 mcg per day, I had burning rashes on chest up to my ears. Was taken to ER 3x for tachycardia, heart failure, thyroid failure, sweating, confusion, arythmia, panic attacks, nausea, pain, twitching on left side of body and more. Thyroid failure continued after stopping medication still til today not recovered. It is 10 months after the fact and I have permanent damage. Tachycardia, nervous system, thyroid dysfunction, hair loss, excessive weight gain, 4 hrs of functionality per day at most. I lost the ability to work and function like a normal person at 43 years old. I cannot exercise nor do simple chores without raising heart rate excessively and blood pressure. I had perfect blood pressure and heart function prior to taking Cytomel.”

1 / 10
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Cypress · February 26, 2021

Cytomel (liothyronine): “I self diagnosed that my body wasn’t converting my synthroid into T3, and an endocrinologist agreed. I tried reducing Synthroid and adding desiccated T3 first, felt great, but I broke out with acne. Cytomel has worked in giving me much more energy, I can get by on 7/8 hours sleep instead of needing 10! I had arm pain at first, which went away with altering the dosage, then some unexplained abdominal pain, that disappeared. I am very happy with cytomels effects in giving me more energy! I used to need to take a cat nap at work to get through the day!”

9 / 10
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KS555 · August 17, 2018

Cytomel (liothyronine): “Glad this med has helped some, but for me it was a four-year nightmare. The anxiety was horrendous. As in disabling. Sweating, temper was on a hair trigger, hot flushing on my back, (TSH around 0). Even went into the hospital for two days to have my heart checked out, which was fine. I started noticing I would feel more normal each time the med dose was missed. Started coming down 1/4 pill at a time and each time it helped. Finally came down to 1/4 pill in addition to my 88 mcg Levo. I was exhausted by 11 am, and my TSH was 6, but at least I wasn't peeling myself off the ceiling and I was calm. Finally went off it entirely, and the anxiety, although not completely gone, was vastly improved. I upped my Levo to 100 mcg and felt dramatically better. It's in process now and I wish I had not wasted four years of my life on this med.”

2 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.