Liothyronine for Underactive Thyroid User Reviews (Page 3)
Brand names: Cytomel, Triostat
Liothyronine has an average rating of 6.4 out of 10 from a total of 69 reviews for the treatment of Underactive Thyroid. 59% of reviewers reported a positive experience, while 38% reported a negative experience.
Reviews for Liothyronine
- Kitten
- Taken for 1 to 6 months
- September 27, 2020
"I was on NP when it was recalled the first time & swapped to Synthroid after going to the ER 3Xs. Synthroid 50 & Cytomel(liothyronine) 5mcg. At first I thought it was just me so I tried Cytomel twice w/Synthroid (gave me head pressure) and once w/Tirosint (In 3 months). On all 3 occasions that I took Cytomel once I reached 15mcg+ dose for the week it gave me side effects of being depressed, anxious, insomniac, palpitations and even advanced me to menstruate a week early (all 3 times)! I want T3 so bad that I repeatedly tried to make it work. It’s just not for me."
- Lucas
- Taken for less than 1 month
- July 22, 2022
Cytomel (liothyronine) "I have Hashimoto's disease, and hypothyroidism with it. I was on Tirosint for a while and all the other T4 medications: Levothyroxine, Synthroid, Tirosint. This Cytomel makes me feel amazing and turns my brain back on immediately after taking it. Cytomel also seems to get rid of almost all the horrible joint pain and muscle aches from the other thyroid medications. It also helps to reduce my muscle stiffness and gets rid of those pesky muscle spasms. I think that all the T4 drugs actually cause more pain all over the body, but they are usually effective at getting rid of hypothyroid symptoms. I noticed this after I forget to take my Synthroid for one day, less pain but more fatigue."
- Feeli...
- Taken for 6 months to 1 year
- May 11, 2019
"Diagnosed with Hashimotos June 2018. Since I can't convert T4 to T3, I was put on Cytomel increasing by 5 mcg every 6 weeks until my TSH was in optimal range, which took 6 months. I felt better than I did in years. Then, I became hyperthyroid, but was having symptoms of both hypo and hyper . So, my dose was decreased and was told I didn't have to be seen for a year. Last month, I pleaded to have my TSH tested again. My TSH was 45.0! Thinking it was a lab error, I got retested five days later and it was 80.1! My endo DOUBLED my dose of Cytomel ( and my TSH went down to 25.0) However, I felt like I was on steroids and begged him to lower dose. He did, but now I am gaining weight, bloating, ( post-menopausal, so its not related to menstruation) I feel horrible again."
- Realj...
- December 12, 2020
"I have hashimoto's. I had been medicated on synthroid and wanted to change after reading all the thyroid books about t3. I took ndt for a couple of years and when I had labs done for a hysterectomy they were so bad I had to put surgery off for a year. I then went on tirosint and begged my endo for t3 cause everyone said my numbers weren't optimal. She put me on 5mcg and I have taken that with 88mcg tirosint for over a year. I have had cycling depression the whole time and slowly put in weight no matter what I do. Recently had a bad flare and doc said maybe it's the t3. Stop taking it. I did and a lot of my pain and fatigue lifted. I tried re dosing several times and everyone in my support group is shunning me because I want to quit. I am withdrawing now and hope that is over soon. I am absolutely glad that it works for some people but I have had all the cortisol anemia and other testing and it's definitely the med causing this! It isn't for everyone!"
Are you taking this medicine?
- Journ...
- Taken for 5 to 10 years
- April 23, 2022
Cytomel (liothyronine) "Takng Synthroid for Hashimoto’s and continued to have fatigue, muscle aches and cramps. Adding Doctor generic Liothyronine was like taking nothing. Switching to brand name Cytomel 5 mcg 2x daily, I felt normal first time in 10 years. Muscle aches/cramping gone, good energy and mental focus returned. I have my heart under control and I’m still on Cytomel. Hair loss I've also had, and you need to have your selenium levels tested. I had some doctor prescribed supplements I had to stop because they contained selenium and it built up. Right now the biggest problem is that I can’t GET my Cytomel Rx filled because Pfizer has some backorder that’s gone on for two months with no explanation. I have to take generic liothyrinine for now; fatigue and muscle cramps are back."
- Aimee
- Taken for 1 to 2 years
- November 18, 2021
"I had a lot of side effects after being on this medicine for about year. At first it helped my energy level but then I had rapidly changing moods, insomnia, sweating, anger/irritability feeling like I might go crazy/jump out of my skin, severe bloating all over, but the worst part was the feeling of depersonalization/derealization. Scary! Lowering the dose down from 10 to 5mcgs didn’t help. I’ll just stick with Armour without this added. Check out the list of side effects for this drug on Mayo Clinic’s site, it’s not pretty."
- Elaine
- Taken for less than 1 month
- May 15, 2016
"When I was first diagnoised the doctor gave me levothyroxine, which uses lactose as a binder for the chemicals. I had a huge reaction to the pill. I felt like I wanted to get out of my skin, Bad stuff. So I started taking the dessicated thyroid, which was much better and I have been on it for many years. Recently, one doctor changed to liothyroine . I got huge headaches that would not go away no matter what I took. In two days of taking the pills, I stopped taking it on my own and switched back to the one that I had been on for so long. The dosage now has to be increased, but at least I will not get the headaches."
- Chris...
- Taken for less than 1 month
- June 12, 2016
"I started taking sigmapharm brand liothyronine. Almost immediately I got terrible tremors that last for hours. I was taking a very low dose 25mcg. After a week I also got a hypoglycemia attack, and I am not diabetic. Discontinuing and going to try perrigo brand liothyronine."
- SBD
- Taken for 5 to 10 years
- March 14, 2020
"I was put on cytomel for drug resistant depression by my psych. It worked great for several years then pharma company started buying from Canada who bought it from India. I went downhill like a sack of rocks. Then couldn’t get cytomel at all and put on generic lyothronine. It got bad enough with energy, jitters and cognitions that I now have home healthcare. Finally after two months of not having any I felt better. Not great by a long shot. Got a new bottle that I had hidden and started taking it again. Just like when switched to generic I stay freezing cold for several hours then start sweating. I think I’m going off"
- Rocker
- Taken for 1 to 2 years
- January 1, 2022
Cytomel (liothyronine) "Palpitation's even at small 5mcg dose. I would use Taurine to off set palps.. ITCHY PIN like sensation's on arms after 1 year use! Like needle's coming out of skin! It took about 3 weeks off use to get rid of it. I use natural desiccated NP hormone during the Cytomel."
- Esper...
- Taken for less than 1 month
- February 11, 2023
"I have had hypothyroidism for 20 years and it caused my hair to fall out in clumps and caused swelling, especially my face which made me feel self-conscience. I am now taking liothyronine (T3) along with levothyroxine. It made a huge difference within a week of taking it. My face is back to normal and I couldn't be happier just with that alone. My hair stopped falling out from the first day of taking it. If anyone is struggling just don't give up and keep asking different doctors that are willing to help. It is very expensive even with my insurance but well worth it in my opinion."
- 2Hope
- Taken for less than 1 month
- May 18, 2022
"1st time user. Hashimoto's diagnosis. Dr prescribed 10mcg per day. Having a bad feeling about the dose I took only half of the dose and I am glad I did because the side effects were immediate and strong. My heart was racing, I couldn't concentrate at all, as if I had ADHD. I've been extremely thirsty despite appropriate hydration. Day 2 and now I have a rash on my legs and torso. I am quitting this treatment right now."
- Rain
- Taken for 2 to 5 years
- April 13, 2024
Cytomel (liothyronine) "Cytomel works, but you have to make sure you are on the correct dose. Some people need a very high amount of T3 in their system, some very little. I’ve heard of a doctor who was on 400 mcg of T3 a day. I was taking 150 mcg per day, splitting it into two doses (while low carb). My hair did not fall out. It can shed for the first 3 to 6 months, but then it grows back in. I’ve always had very thick hair and Cytomel kept it that way. If you take too much, or too little, I imagine this may cause your hair to shed. If you do not heal the underlying medical issue, and eat poorly, you will need to take more and more over time and your doctor may not approve the higher dose, so you’re left with hypothyroidism even on T3. You must change your diet. If you’re someone who hasn't changed your diet (removed wheat gluten, grains, sugar, nightshades, etc.) and you feel well and slim/healthy on T3, that’s very rare, especially if you have Hashimoto's. Eat well (red meat, etc.)"
- me2buc
- Taken for 1 to 6 months
- November 15, 2012
Cytomel (liothyronine) "This medication has been a life saver for me. I don't know if it works really well for depression or if I was hypothyroid but it has saved my life and I am so very thankful for it."
- 69me
- Taken for less than 1 month
- June 5, 2013
Cytomel (liothyronine) "I have been on this for a day and my aches and pains have subsided. I will not give it a 10 because I am not "perfect" yet. "
- nashdo
- June 4, 2015
"as a supplement to levothyroxine it has been a night and day difference. I no longer sleep all the time and can think clearly. I actually want to do things now."
- Anonymous
- Taken for less than 1 month
- February 6, 2015
Cytomel (liothyronine) "Can't take it because my heart rate won't go below 90."
- Summer
- Taken for less than 1 month
- November 26, 2019
Cytomel (liothyronine) "I started taking this today, due to a low T3 test result, very low dose. It made me feel absolutely insane, crazy. I couldn’t concentrate, I felt awful. I don’t think I’ll take it again."
- JET
- Taken for 1 to 6 months
- October 23, 2012
"Added 0.5 mcg to my Tirosint in August - nothing much changed until last week when I started taking this 1 hour after my Tirosint - down 5 lbs in one week! I have changed nothing else."
- abbaz...
- November 14, 2010
"The first day I took it, my constipation and heart flutters disappeared, and my energy came back. I believe I'll need a larger dose soon, but so far no complaints at all."
- Shorty
- March 25, 2018
"Has anyone taken this for depression? I've been on it for four days so far no results only feel tired. How long does it take to work?"
- Tuscany...
- Taken for 1 to 2 years
- August 6, 2015
"Side effects was a rash in legs, abdomen....discontinued medication & so did the symptoms."
Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.
Learn more about Underactive Thyroid
Care guides
- Acquired Hypothyroidism in Children
- Congenital Hypothyroidism in Children
- Hypothyroidism
- Hypothyroidism in Pregnancy
- Induced Thyroid Disorders
- Subclinical Hyperthyroidism
- Subclinical Hypothyroidism
Symptoms and treatments
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"After pestering my doctor to take my symptoms seriously It was time for my amazing doctor to LISTEN TO ME AND LEARN FROM MY EXAMPLE). I started Liothyronine, 25mg because I'm 57 and have T2D. It was as if someone had turned on the lights in my life! I could now function like other people, with the energy to exercise, do self-care, my brain would focus again, and I have done so well that despite fibromyalgia and bpd2. I am able to go back to work part-time, at my request, because I am bored and I have too many gifts to offer the world that were hidden for too long. *Caveat: I did have to reduce the dose to 12.5 when I stopped sleeping and was walking 5 miles a day. That was TOO MUCH energy! My lab work looks great. Glad my doc finally listened! Have my life back, hooray!!"