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Liothyronine and Heart Palpitations: What Users Say

Brand names: Cytomel, Triostat

Heart palpitations: mentioned by 11 users (11.2%)

Based on user experiences from 98 Liothyronine reviews, the following table shows the most commonly mentioned side effects.

All user comments are moderated by Drugs.com. Each review is verified for relevance and screened for inappropriate content. Side effects are user-reported and not clinically verified.

anxiety 11.2%
heart palpitations 11.2%
depression 9.2%
weight gain 9.2%
hair loss 8.2%
sweating 8.2%
fatigue 7.1%
headaches 7.1%
insomnia 7.1%
tremors 7.1%

Reviews for Liothyronine

Commonly mentioned side effects
  • Cou...
  • Taken for 6 months to 1 year
  • January 18, 2020

Liothyronine for Underactive Thyroid "Hashimoto's patient. Take 88 mcg of Synthroid and took 5 mcg of Cytomel for almost a year. Felt better at first and then felt completely insane. Mood swings, anxiety, depression, rage, tachycardia, and hand tremors. Sketchy stuff that. If you feel crazy, cut the Cytomel before you get on or up your antidepressants."

3 / 10
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103 Report
  • Ran...
  • Taken for less than 1 month
  • December 27, 2019

Liothyronine for Underactive Thyroid "Upon 5 days of taking Cytomel at a dose of 5 mcg per day, I had burning rashes on my chest up to my ears. Was taken to the ER 3x for tachycardia, heart failure, thyroid failure, sweating, confusion, arrhythmia, panic attacks, nausea, pain, twitching on the left side of my body, and more. Thyroid failure continued after stopping the medication, still to today not recovered. It is 10 months after the fact, and I have permanent damage. Tachycardia, nervous system, thyroid dysfunction, hair loss, excessive weight gain, 4 hours of functionality per day at most. I lost the ability to work and function like a normal person at 43 years old. I cannot exercise nor do simple chores without raising my heart rate excessively and blood pressure. I had perfect blood pressure and heart function prior to taking Cytomel."

1 / 10
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68 Report
  • Ran...
  • Taken for less than 1 month
  • December 27, 2019

Liothyronine for Underactive Thyroid "Upon 5 days of taking Cytomel at a dose of 5 mcg per day, I had burning rashes on my chest up to my ears. Was taken to the ER 3x for tachycardia, heart failure, thyroid failure, sweating, confusion, arrhythmia, panic attacks, nausea, pain, twitching on the left side of my body, and more. Thyroid failure continued after stopping the medication, still to today not recovered. It is 10 months after the fact, and I have permanent damage. Tachycardia, nervous system, thyroid dysfunction, hair loss, excessive weight gain, 4 hours of functionality per day at most. I lost the ability to work and function like a normal person at 43 years old. I cannot exercise nor do simple chores without raising my heart rate excessively and blood pressure. I had perfect blood pressure and heart function prior to taking Cytomel."

1 / 10
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68 Report
  • Sam...
  • Taken for 1 to 2 years
  • June 16, 2019

Liothyronine for Hypothyroidism, After Thyroid Removal "Cytomel is causing debilitating symptoms such as severe muscle cramps/spasms and muscle pain, insomnia, ravenous appetite, profuse sweating, and palpitations. When I stopped taking it, I got better. I tried to reintroduce it, and to my horror, the severe spasms returned. The prescribed muscle relaxers hardly work. The endocrinologist said my symptoms are not related to the prescribed medication or to my thyroid condition! I disagree. I've had problems with Armour in the distant past. For some reason, I can't take Cytomel or Armour long term."

2 / 10
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44 Report
  • Ter...
  • December 6, 2015

Liothyronine for Underactive Thyroid "I was on Cytomel for a couple of years. Then my dose got increased along with my Synthroid medication dose. I began having tremors, heart palpitations, and tachycardia. It was a terrifying experience! My symptoms almost entirely went away when going off this medication, but I feel as though my heart was dramatically affected and I don't know yet whether or not it was actually even damaged."

1 / 10
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72 Report

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  • Ter...
  • December 6, 2015

Liothyronine for Underactive Thyroid "I was on Cytomel for a couple of years. Then my dose got increased along with my Synthroid medication dose. I began having tremors, heart palpitations, and tachycardia. It was a terrifying experience! My symptoms almost entirely went away when going off this medication, but I feel as though my heart was dramatically affected and I don't know yet whether or not it was actually even damaged."

1 / 10
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72 Report
  • Kit...
  • Taken for 1 to 6 months
  • September 27, 2020

For Underactive Thyroid "I was on NP when it was recalled the first time and swapped to Synthroid after going to the ER 3 times. Synthroid 50 and Cytomel (liothyronine) 5 mcg. At first, I thought it was just me, so I tried Cytomel twice with Synthroid (gave me head pressure) and once with Tirosint (in 3 months). On all 3 occasions that I took Cytomel, once I reached a 15 mcg+ dose for the week, it gave me side effects of being depressed, anxious, insomniac, palpitations, and even advanced me to menstruate a week early (all 3 times)! I want T3 so bad that I repeatedly tried to make it work. It’s just not for me."

1 / 10
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18 Report
  • MEa...
  • Taken for 1 to 6 months
  • March 21, 2021

Liothyronine for Underactive Thyroid "This medication is horrible! I have had severe adverse reactions on both the brand name and generic form. Painful limp knees, tachycardia, palpitations, and all of my hair fell out! Never again will I take this medication. It’s not worth my life."

1 / 10
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19 Report
  • MEa...
  • Taken for 1 to 6 months
  • March 21, 2021

Liothyronine for Underactive Thyroid "This medication is horrible! I have had severe adverse reactions on both the brand name and generic form. Painful limp knees, tachycardia, palpitations, and all of my hair fell out! Never again will I take this medication. It’s not worth my life."

1 / 10
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19 Report
  • Roc...
  • Taken for 1 to 2 years
  • January 1, 2022

Liothyronine for Underactive Thyroid "Palpitations even at a small 5 mcg dose. I would use Taurine to offset palps.. Itchy pin-like sensations on arms after 1 year of use! Like needles coming out of skin! It took about 3 weeks off use to get rid of it. I use natural desiccated NP hormone during the Cytomel."

1 / 10
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8 Report
  • abb...
  • November 14, 2010

For Underactive Thyroid "The first day I took it, my constipation and heart flutters disappeared, and my energy came back. I believe I'll need a larger dose soon, but so far no complaints at all."

10 / 10
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45 Report

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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.