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Soul Pattinson Colourfree Childrens Paracetamol Side Effects

Generic name: acetaminophen

Medically reviewed by Drugs.com. Last updated on May 21, 2022.

Note: This document contains side effect information about acetaminophen. Some of the dosage forms listed on this page may not apply to the brand name Soul Pattinson Colourfree Childrens Paracetamol.

For the Consumer

Applies to acetaminophen: capsule, capsule liquid filled, elixir, liquid, powder, solution, suppository, suspension, tablet, tablet chewable, tablet disintegrating, tablet extended release

Other dosage forms:

Side effects requiring immediate medical attention

Along with its needed effects, acetaminophen (the active ingredient contained in Soul Pattinson Colourfree Childrens Paracetamol) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking acetaminophen:

Rare

  • Bloody or black, tarry stools
  • bloody or cloudy urine
  • fever with or without chills (not present before treatment and not caused by the condition being treated)
  • pain in the lower back and/or side (severe and/or sharp)
  • pinpoint red spots on the skin
  • skin rash, hives, or itching
  • sore throat (not present before treatment and not caused by the condition being treated)
  • sores, ulcers, or white spots on the lips or in the mouth
  • sudden decrease in the amount of urine
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • yellow eyes or skin

Get emergency help immediately if any of the following symptoms of overdose occur while taking acetaminophen:

Symptoms of overdose

  • Diarrhea
  • increased sweating
  • loss of appetite
  • nausea or vomiting
  • stomach cramps or pain
  • swelling, pain, or tenderness in the upper abdomen or stomach area

For Healthcare Professionals

Applies to acetaminophen: compounding powder, intravenous solution, oral capsule, oral granule effervescent, oral liquid, oral powder, oral powder for reconstitution, oral suspension, oral tablet, oral tablet chewable, oral tablet disintegrating, oral tablet extended release, rectal suppository

General

In general, acetaminophen (the active ingredient contained in Soul Pattinson Colourfree Childrens Paracetamol) is well-tolerated when administered in therapeutic doses. The most commonly reported adverse reactions have included nausea, vomiting, constipation. Injection site pain and injection site reaction have been reported with the IV product.[Ref]

Hepatic

Common (1% to 10%): Increased aspartate aminotransferase

Rare (less than 0.1%): Increased hepatic transaminases

Frequency not reported: Liver failure[Ref]

Gastrointestinal

Very common (10% or more): Nausea (up to 34%), Vomiting (up to 15%)

Common (1% to 10%): Abdominal pain, diarrhea, constipation, dyspepsia, enlarged abdomen

Frequency not reported: Dry mouth[Ref]

Hypersensitivity

Postmarketing reports: Anaphylaxis, hypersensitivity reactions[Ref]

Hematologic

Common (1% to 10%): Anemia, postoperative hemorrhage

Very rare (less than 0.01%): Thrombocytopenia, leucopenia, neutropenia[Ref]

Dermatologic

Common (1% to 10%): Rash, pruritus

Rare (less than 0.1%): Serious skin reactions such as acute generalized exanthematous pustulosis, Stevens-Johnson syndrome, and toxic epidermal necrolysis

Very rare (less than 0.01%): Pemphigoid reaction, pustular rash, Lyell syndrome[Ref]

Respiratory

Common (1% to 10%): Dyspnea, abnormal breath sounds, pulmonary edema, hypoxia, pleural effusion, stridor, wheezing, coughing[Ref]

Cardiovascular

Common (1% to 10%): Peripheral edema, hypertension, hypotension, tachycardia, chest pain[Ref]

Metabolic

Common (1% to 10%): Hypokalemia, hyperglycemia[Ref]

Nervous system

Common (1% to 10%): Headache, dizziness

Frequency not reported: Dystonia

Musculoskeletal

Common (1% to 10%): Muscle spasms, trismus

Psychiatric

Common (1% to 10%): Insomnia, anxiety

Genitourinary

Common (1% to 10%): Oliguria

Local

Common (1% to 10%): Infusion site pain, injection site reactions

Ocular

Common (1% to 10%): Periorbital edema

Other

Common (1% to 10%): Pyrexia, fatigue

Rare (0.01% to 0.1%): Malaise

Frequently asked questions

More about Soul Pattinson Colourfree Childrens Paracetamol (acetaminophen)

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References

1. "Multum Information Services, Inc. Expert Review Panel"

2. Maddrey WC, Zimmerman HJ "Acetaminophen (paracetamol) hepatotoxicity with regular intake of alcohol: analysis of instances of therapeutic misadventure." Hepatology 22 (1995): 767-73

3. Dundar SV, Haznedaroglu IC, Ozcebe OI, Sayinalp N, Celik I, Gursoy M "Agranulocytosis, plasmacytosis, and thrombocytosis followed by a leukemoid reaction due to acute acetaminophen toxicity." Ann Pharmacother 30 (1996): 762-5

4. Kurtovic J, Riordan SM "Paracetamol-induced hepatotoxicity at recommended dosage." J Intern Med 253 (2003): 240-3

5. Vitols S "Paracetamol hepatotoxicity at therapeutic doses." J Intern Med 253 (2003): 95-8

6. Kaysen GA, Marrama MA, Menke DJ, Pond SM, Roper MH "Combined hepatic and renal injury in alcoholics during therapeutic use of acetaminophen." Arch Intern Med 145 (1985): 2019-23

7. O'Dell JR, Burnett DA, Zetterman RK "Centrilobular hepatic fibrosis following acetaminophen-induced hepatic necrosis in an alcoholic." JAMA 255 (1986): 2636-7

8. Adler E, Benjamin SB, Seeff LB, Zimmerman HJ, Cuccherini BA "Acetaminophen hepatotoxicity in alcoholics." Ann Intern Med 104 (1986): 399-404

9. Frankel RJ, Henry JA, Minton NA "Fatal paracetamol poisoning in an epileptic." Hum Toxicol 7 (1988): 33-4

10. Keaton MR "Acute renal failure in an alcoholic during therapeutic acetaminophen ingestion." South Med J 81 (1988): 1163-6

11. Goetz MB, Shriner K "Severe hepatotoxicity in a patient receiving both acetaminophen and zidovudine." Am J Med 93 (1992): 94-6

12. Wendon JA, Keays R, Harrison PM, et al. "Intravenous acetylcysteine in paracetamol induced fulminant hepatic failure: a prospective controlled trial." BMJ 303 (1991): 1026-9

13. Blaiklock RG, Rumore MM "Influence of age-dependent pharmacokinetics and metabolism on acetaminophen hepatotoxicity." J Pharm Sci 81 (1992): 203-7

14. Mofenson HC, Steckler G, Nawaz H, Caraccio TR "Acetaminophen induced pancreatitis." Clin Toxicol 29 (1991): 223-30

15. Kumar S, Rex DK "Failure of physicians to recognize acetaminophen hepatotoxicity in chronic alcoholics." Arch Intern Med 151 (1991): 1189-91

16. Block R, Pennington CR, Jankowski JA, Lacoux P "Does hypothermia protect against the development of hepatitis in paracetamol overdose?" Anaesthesia 47 (1992): 789-91

17. Batey RG, Brotodihardjo AE, Farrell GC, Byth K "Hepatotoxicity from paracetamol self-poisoning in Western Sydney: a continuing challenge." Med J Aust 157 (1992): 382-5

18. Tolman KG, Johnson GK "Chronic liver disease and acetaminophen." Ann Intern Med 87 (1977): 302-4

19. Barwick KW, Winfield JB, Little WC, McJunkin B "Fatal massive hepatic necrosis following acetaminophen overdose." JAMA 236 (1976): 1874-5

20. Block R "Liver failure induced by paracetamol." BMJ 306 (1993): 457

21. Heatley V, Boon A, Daly M, Wong V "Paracetamol and acute biliary pain with cholestasis." Lancet 342 (1993): 869

22. Bray GP "Liver failure induced by paracetamol." BMJ 306 (1993): 157-8

23. Lee WM "Acute liver failure." Am J Med 96 (1994): 3-9

24. Bonkovsky HL, Banner B, Galinsky RE, Jones DP, Kane RE "Acute hepatic and renal toxicity from low doses of acetaminophen in the absence of alcohol abuse or malnutrition - evidence for increased susceptibility to drug toxicity due to cardiopulmonary and renal insufficiency." Hepatology 19 (1994): 1141-8

25. Cheung L, Potts RG, Meyer KC "Acetaminophen treatment nomogram." N Engl J Med 330 (1994): 1907-8

26. Hartleb M "Do thyroid hormones promote hepatotoxicity to acetaminophen?" Am J Gastroenterol 89 (1994): 1269-70

27. Daya MR, Douglas Dr, Smilkstein MJ "Acetaminophen poisoning and liver function." N Engl J Med 331 (1994): 1310-1

28. Whitcomb DC "Acetaminophen poisoning and liver function." N Engl J Med 331 (1994): 1311

29. Cheung L, Meyer KC "Acetaminophen poisoning and liver function." N Engl J Med 331 (1994): 1311-2

30. Block GD, Whitcomb DC "Association of acetaminopphen hepatotoxicity with fasting and ethanol use." JAMA 272 (1994): 1845-50

31. Bonkovsky HL "Acetaminophen hepatotoxicity, fasting, and ethanol." JAMA 274 (1995): 301

32. Nelson EB, Temple AR "Acetaminophen hepatotoxicity, fasting, and ethanol." JAMA 274 (1995): 301

33. Carracio TR, Mofenson HC, Singer AJ "The temporal profile of increased transaminase levels in patients with acetaminophen-induced liver dysfunction." Ann Emerg Med 26 (1995): 49-53

34. Lee WM "Medical progress: drug-induced hepatotoxicity." N Engl J Med 333 (1995): 1118-27

35. Settipane RA, Stevenson DD "Cross sensitivity with acetaminophen in aspirin-sensitive subjects with asthma." J Allergy Clin Immunol 84 (1989): 26-33

36. Grilliat JP, Van Diem L "Anaphylactic shock induced by paracetamol." Eur J Clin Pharmacol 38 (1990): 389-90

37. Plomley R, Czarny D, Leung R "Paracetamol anaphylaxis." Clin Exp Allergy 22 (1992): 831-3

38. Greenberger PA, Doan T "Nearly fatal episodes of hypotension, flushing, and dyspnea in a 47- year-old woman." Ann Allergy 70 (1993): 439-44

39. Kalyoncu AF "Acetaminophen hypersensitivity and other analgesics." Ann Allergy 72 (1994): 285

40. Doan T "Acetaminophen hypersensitivity and other analgesics - response." Ann Allergy 72 (1994): 285

41. Hiruma M, Ishibashi A, Noguchi H, Kawada A "Fixed drug eruption induced by acetaminophen in a 12-year-old girl." Int J Dermatol 35 (1996): 148-9

42. BenAmitai D, Garty BZ, Halevi A "Toxic epidermal necrolysis associated with acetaminophen ingestion." Ann Pharmacother 34 (2000): 32-4

43. Pinkhas J, Shoenfeld Y, Livni E, Shaklai M "Thrombocytopenia from acetaminophen." N Engl J Med 303 (1980): 47

44. Benito AI, Aster RH, Birenbaum J, Bougie DW, Sanchez-Abarca LI, Torres R "Acute thrombocytopenia caused by sensitivity to the glucuronide conjugate of acetaminophen." Blood 109 (2007): 3608-9

45. Munro DD, Thomas RH "Fixed drug eruption due to paracetamol." Br J Dermatol 115 (1986): 357-9

46. Guccione JL, Neldner KH, Cobos E, Zemtsov A "Acquired purpura fulminans induced by alcohol and acetaminophen - successful treatment with heparin and vitamin-k." Arch Dermatol 129 (1993): 1267-9

47. Filipe PL, Decastro JC, Freitas JP, Silva R "Drug eruption induced by acetaminophen in infectious mononucleosis." Int J Dermatol 34 (1995): 220-1

48. Kondo K, Hamada H, Kohno N, Hiwada K, Inoue Y, Yokoyama A "Acetaminophen-induced eosinophilic pneumonia." Chest 104 (1993): 291-2

49. Brown G "Acetaminophen-induced hypotension." Heart Lung 25 (1996): 137-40

50. Jones G, Koulouris Z, Tierney MG "Metabolic acidosis and coma following a severe acetaminophen overdose." Ann Pharmacother 33 (1999): 1191-4

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.