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Sonata Side Effects

Generic Name: zaleplon

Note: This document contains side effect information about zaleplon. Some of the dosage forms listed on this page may not apply to the brand name Sonata.

For the Consumer

Applies to zaleplon: oral capsule

Along with its needed effects, zaleplon (the active ingredient contained in Sonata) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking zaleplon:

Less common
  • Anxiety
  • blurred or double vision
  • not feeling like oneself
Rare
  • Nosebleed
  • seeing, hearing, smelling, or feeling things that are not there

Get emergency help immediately if any of the following symptoms of overdose occur while taking zaleplon:

Symptoms of overdose
  • Confusion
  • clumsiness or unsteadiness, severe
  • dizziness or fainting
  • drowsiness, severe
  • weak muscle tone
  • troubled breathing
  • unusual dullness or feeling sluggish

Some side effects of zaleplon may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Dizziness
  • headache
  • muscle pain
  • nausea
Less common
  • Abdominal pain
  • burning, prickling, or tingling sensation
  • constipation
  • cough
  • difficulty concentrating
  • drowsiness
  • dryness of mouth
  • excess muscle tone
  • eye pain
  • fever
  • heartburn, indigestion, or acid stomach
  • itching
  • itching or burning eyes
  • joint stiffness and/or pain
  • memory loss
  • menstrual pain
  • mental depression
  • nervousness
  • sensitive hearing
  • severe headache
  • shortness of breath
  • skin rash
  • tightness in chest
  • trembling or shaking
  • troubled breathing
  • unusual weakness or tiredness
  • wheezing

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

  • Abdominal and muscle cramps
  • convulsions (seizures)
  • increased sweating
  • sadness
  • trembling or shaking
  • vomiting

For Healthcare Professionals

Applies to zaleplon: oral capsule

Nervous system

Very common (10% or more): Headache (42%)
Common (1% to 10%): Dizziness, amnesia, confusion, hypertonia, hypesthesia, paresthesia, somnolence, tremor, vertigo, migraine, taste perversion
Uncommon (0.1% to 1%): Abnormal gait, ataxia, circumoral paresthesia, hyperesthesia, hyperkinesia, hypotonia, incoordination, neuralgia, nystagmus
Rare (less than 0.1%): CNS stimulation, cerebral ischemia, dysarthria, dystonia, facial paralysis, hypokinesia, myoclonus, neuropathy, psychomotor retardation, decreased reflexes, increased reflexes, slurred speech, stupor
Frequency not reported: Seizures[Ref]

Dermatologic

Common (1% to 10%): Pruritus, rash
Uncommon (0.1% to 1%): Ecchymosis, acne, alopecia, contact dermatitis, dry skin, eczema, maculopapular rash, skin hypertrophy, sweating, urticaria, vesiculobullous rash
Rare (less than 0.1%): Purpura, melanosis, psoriasis, pustular rash, skin discoloration

Gastrointestinal

Common (1% to 10%): Nausea, abdominal pain, colitis, constipation, dry mouth, dyspepsia
Uncommon (0.1% to 1%): Eructation, esophagitis, flatulence, gastritis, gastroenteritis, gingivitis, glossitis, mouth ulceration, stomatitis
Rare (less than 0.1%): Aphthous stomatitis, bruxism, cardiospasm, cheilitis, cholelithiasis, duodenal ulcer, dysphagia, enteritis, gum hemorrhage, increased salivation, intestinal obstruction, peptic ulcer, tongue discoloration, tongue edema, ulcerative stomatitis[Ref]

Genitourinary

Common (1% to 10%): Dysmenorrhea
Uncommon (0.1% to 1%): Breast pain, rectal hemorrhage, bladder pain, melena, cystitis, decreased urine stream, dysuria, hematuria, menorrhagia, metrorrhagia, urinary frequency, urinary incontinence, urinary urgency, vaginitis
Rare (less than 0.1%): Albuminuria, delayed menstrual period, leukorrhea, menopause, urethritis, urinary retention, vaginal hemorrhage[Ref]

Metabolic

Common (1% to 10%): Anorexia
Uncommon (0.1% to 1%): Increased appetite, gout, hypercholesteremia, weight gain
Rare (less than 0.1%): Weight loss[Ref]

Musculoskeletal

Common (1% to 10%): Back pain, arthralgia, arthritis, myalgia
Uncommon (0.1% to 1%): Neck rigidity, arthrosis, bursitis, joint disorder (mainly swelling, stiffness, pain), myasthenia, tenosynovitis
Rare (less than 0.1%): Myositis, osteoporosis, trismus[Ref]

Ocular

Common (1% to 10%): Abnormal vision, eye pain, conjunctivitis
Uncommon (0.1% to 1%): Diplopia, dry eyes, photophobia, watery eyes
Rare (less than 0.1%): Ptosis, abnormality of accommodation, blepharitis, cataract specified, corneal erosion, eye hemorrhage, glaucoma, retinal detachment, visual field defect[Ref]

Other

Common (1% to 10%): Asthenia, malaise, photosensitivity reaction, peripheral edema, ear pain, hyperacusis, parosmia, chest pain, fever
Uncommon (0.1% to 1%): Substernal chest pain, chills, face edema, generalized edema, hangover effect, tinnitus, thirst[Ref]

Psychiatric

Common (1% to 10%): Depersonalization, hallucinations, anxiety, depression, nervousness, abnormal thinking (mainly difficulty concentrating)
Uncommon (0.1% to 1%): Agitation, emotional lability, apathy, euphoria, insomnia, decreased libido, impotence
Rare (less than 0.1%): Delusions, hostility, sleep talking, sleep walking
Postmarketing reports: Nightmares

Respiratory

Common (1% to 10%): Epistaxis, bronchitis
Uncommon (0.1% to 1%): Asthma, dyspnea, laryngitis, pneumonia, snoring, voice alteration
Rare (less than 0.1%): Pulmonary embolus, apnea, hiccup, hyperventilation, pleural effusion, increased sputum[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Angina pectoris, bundle branch block, hypertension, hypotension, palpitation, syncope, tachycardia, vasodilation, ventricular extrasystoles
Rare (less than 0.1%): Bigeminy, cyanosis, pericardial effusion, postural hypotension, sinus bradycardia, thrombophlebitis, ventricular tachycardia

Hematologic

Uncommon (0.1% to 1%): Anemia, lymphadenopathy
Rare (less than 0.1%): Eosinophilia, leukocytosis, lymphocytosis

Renal

Uncommon (0.1% to 1%): Kidney calculus, kidney pain

Endocrine

Rare (less than 0.1%): Diabetes mellitus, goiter, hypothyroidism

Hepatic

Rare (less than 0.1%): Abnormal liver function tests, bilirubinemia, increased AST (SGOT), increased ALT (SGPT), biliary pain

Hypersensitivity

Postmarketing reports: Anaphylactic/anaphylactoid reactions

References

1. "Product Information. Sonata (zaleplon)" Wyeth-Ayerst Laboratories, Philadelphia, PA.

Some side effects of Sonata may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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