Sonata Dosage
Generic name: ZALEPLON 5mg
Dosage form: capsule
Drug class: Miscellaneous anxiolytics, sedatives and hypnotics
Medically reviewed by Drugs.com. Last updated on Dec 3, 2024.
The dose of Sonata should be individualized. The recommended dose of Sonata for most nonelderly adults is 10 mg. For certain low weight individuals, 5 mg may be a sufficient dose. Although the risk of certain adverse events associated with the use of Sonata appears to be dose dependent, the 20 mg dose has been shown to be adequately tolerated and may be considered for the occasional patient who does not benefit from a trial of a lower dose. Doses above 20 mg have not been adequately evaluated and are not recommended.
Sonata should be taken immediately before bedtime or after the patient has gone to bed and has experienced difficulty falling asleep (see PRECAUTIONS.). Taking Sonata with or immediately after a heavy, high-fat meal results in slower absorption and would be expected to reduce the effect of Sonata on sleep latency (see Pharmacokinetics under CLINICAL PHARMACOLOGY).
Special Populations
Elderly patients and debilitated patients appear to be more sensitive to the effects of hypnotics, and respond to 5 mg of Sonata. The recommended dose for these patients is therefore 5 mg. Doses over 10 mg are not recommended.
Hepatic insufficiency: Patients with mild to moderate hepatic impairment should be treated with Sonata 5 mg because clearance is reduced in this population. Sonata is not recommended for use in patients with severe hepatic impairment.
Renal insufficiency: No dose adjustment is necessary in patients with mild to moderate renal impairment. Sonata has not been adequately studied in patients with severe renal impairment.
An initial dose of 5 mg should be given to patients concomitantly taking cimetidine because zaleplon clearance is reduced in this population (see Drug Interactions under PRECAUTIONS).
Frequently asked questions
More about Sonata (zaleplon)
- Check interactions
- Compare alternatives
- Reviews (71)
- Drug images
- Side effects
- During pregnancy
- Generic availability
- Drug class: miscellaneous anxiolytics, sedatives and hypnotics
- Breastfeeding
Patient resources
Professional resources
Related treatment guides
See also:
Ativan
Ativan is a benzodiazepine used to treat anxiety disorders or anxiety associated with depression ...
Benadryl
Benadryl is an antihistamine and is used to treat sneezing, runny nose, itching and other ...
Ozempic
Learn about Ozempic (semaglutide) for type 2 diabetes treatment, weight management, cardiovascular ...
Ambien
Ambien (zolpidem) is a prescription sedative used to treat insomnia, helping you fall asleep and ...
Lunesta
Lunesta is a sedative and is used to treat insomnia. Lunesta's effects typically begin within 30 ...
Eszopiclone
Eszopiclone (brand name Lunesta) is a sedative and is used to treat insomnia. Eszopiclone's effects ...
Temazepam
Temazepam is used to treat insomnia (trouble sleeping). Learn about side effects, interactions and ...
Doxepin
Doxepin systemic is used for anxiety, depression, insomnia, irritable bowel syndrome, major ...
Diphenhydramine
Diphenhydramine is an antihistamine used to treat sneezing, runny nose, itching, hives and other ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.