Sleep-ettes D Side Effects
Generic Name: diphenhydramine
Note: This document contains side effect information about diphenhydramine. Some of the dosage forms listed on this page may not apply to the brand name Sleep-ettes D.
For the Consumer
Applies to diphenhydramine: oral capsules and tablets, parenteral injection
Side effects include:
Sedation, sleepiness, dizziness, disturbed coordination, epigastric distress, thickening of bronchial secretions.
For Healthcare Professionals
Applies to diphenhydramine: compounding powder, injectable solution, oral capsule, oral disintegrating strip, oral liquid, oral tablet, oral tablet chewable, oral tablet disintegrating
The most commonly reported side effects included somnolence, dizziness, and incoordination.[Ref]
Common (1% to 10%): Sedation/somnolence/sleepiness, drowsiness, unsteadiness, dizziness, headache, attention disturbance
Rare (0.01% to 0.1%): Extrapyramidal effects, tremor, convulsions
Frequency not reported: Paresthesia, dyskinesia/muscle dyskinesia, vertigo, neuritis, incoordination, psychomotor impairment, activation of epileptogenic foci[Ref]
Drowsiness usually diminishes after a few days.[Ref]
Common (1% to 10%): Dry mouth
Frequency not reported: Gastrointestinal disturbance, nausea, vomiting, constipation, diarrhea, dyspepsia, epigastric distress[Ref]
Common (1% to 10%): Fatigue
Frequency not reported: Lassitude, tinnitus, acute labyrinthitis, asthenia, chills, impaired performance (including impaired driving, work, and/or information processing)[Ref]
Rare (0.01% to 0.1%): Confusion, depression, sleep disturbances
Frequency not reported: Paradoxical excitation/excitation, agitation, increased energy, restlessness, nervousness, euphoria, anxiety, hallucinations, insomnia, irritability[Ref]
Rare (0.01% to 0.1%): Palpitations, hypotension, arrhythmia
Frequency not reported: Tachycardia, chest tightness, extrasystoles[Ref]
Rare (0.01% to 0.1%): Blood disorders
Frequency not reported: Hemolytic anemia, thrombocytopenia, agranulocytosis[Ref]
Rare (0.01% to 0.1%): Hypersensitivity reactions
Frequency not reported: Angioedema, anaphylactic shock[Ref]
Rare (0.01% to 0.1%): Liver dysfunction[Ref]
Frequency not reported: Rash, urticaria, skin rashes, erythema, photosensitivity, pruritus, drug rash, excessive perspiration[Ref]
Frequency not reported: Dyspnea, thickening of bronchial secretions, throat tightening, wheezing, nasal stuffiness, dry nose or throat[Ref]
Frequency not reported: Urinary hesitancy/difficulty/retention, dysuria, early menses[Ref]
Frequency not reported: Blurred vision, dry eyes, diplopia[Ref]
Frequency not reported: Increased appetite, anorexia[Ref]
Frequency not reported: Muscle twitching/weakness[Ref]
1. Cerner Multum, Inc. "Australian Product Information." O 0
2. "Product Information. Benadryl Childrens Allergy Fastmelt (diphenhydrAMINE)." Pfizer U.S. Pharmaceuticals Group, New York, NY.
3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
4. "Product Information. Benadryl (diphenhydramine)." Parke-Davis, Morris Plains, NJ.
Some side effects of Sleep-ettes D may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
More about Sleep-ettes D (diphenhydramine)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- 0 Reviews – Add your own review/rating
- Drug class: anticholinergic antiemetics
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